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We consider a population evolving under mutation and selection. The genotype of an individual is a word of length $\ell$ over a finite alphabet. Mutations occur during reproduction, independently on each locus; the fitness depends on the…

Probability · Mathematics 2017-12-04 Joseba Dalmau

We consider a integro-differential nonlinear model that describes the evolution of a population structured by a quantitative trait. The interactions between traits occur from competition for resources whose concentrations depend on the…

Analysis of PDEs · Mathematics 2011-12-05 Nicolas Champagnat , Pierre-Emmanuel Jabin

We consider a general branching population where the lifetimes of individuals are i.i.d.\ with arbitrary distribution and where each individual gives birth to new individuals at Poisson times independently from each other. In addition, we…

Probability · Mathematics 2017-01-26 Benoit Henry

The fuel-driven process of replication in living systems generates distributions of copied entities with varying degrees of copying accuracy. Here we introduce a thermodynamically consistent ensemble for investigating universal population…

Statistical Mechanics · Physics 2025-02-18 Arthur Genthon , Carl D. Modes , Frank Jülicher , Stephan W. Grill

We are interested in modeling Darwinian evolution resulting from the interplay of phenotypic variation and natural selection through ecological interactions. The population is modeled as a stochastic point process whose generator captures…

Probability · Mathematics 2011-02-01 Benjamin Jourdain , Sylvie Méléard , Wojbor Woyczynski

Evolution in finite populations is often modelled using the classical Moran process. Over the last ten years this methodology has been extended to structured populations using evolutionary graph theory. An important question in any such…

Populations and Evolution · Quantitative Biology 2015-05-25 Karan Pattni , Mark Broom , Jan Rychtar , Lara J. Silvers

We prove the existence and uniqueness of a quasi-stationary distribution for three stochastic processes derived from the model of Muller's ratchet. This model was invented with the aim of evaluating the limitations of an asexual…

Probability · Mathematics 2024-04-02 Mauro Mariani , Etienne Pardoux , Aurélien Velleret

Population structures can be crucial determinants of evolutionary processes. For the Moran process on graphs certain structures suppress selective pressure, while others amplify it (Lieberman et al. 2005 Nature 433 312-316). Evolutionary…

Probability · Mathematics 2014-08-12 Alastair Jamieson-Lane , Christoph Hauert

In a view for a simple model where natural selection at the individual level is confronted to selection effects at the group level, we consider some individual-based models of some large population subdivided into a large number of groups.…

Probability · Mathematics 2023-07-13 Aurélien Velleret

We study the role of demographic fluctuations in typical endemics as exemplified by the stochastic SIRS model. The birth-death master equation of the model is simulated using exact numerics and analysed within the linear noise…

Statistical Mechanics · Physics 2011-06-29 Somdeb Ghose , R. Adhikari

We show that spatial extensions of many-species population dynamics models, such as the Lotka-Volterra model with random interactions we focus on in this work, generically exhibit scale-free correlation functions of population sizes in the…

Statistical Mechanics · Physics 2025-12-09 Thibaut Arnoulx de Pirey

Muller's ratchet is a paradigmatic model for the accumulation of deleterious mutations in a population of finite size. A click of the ratchet occurs when all individuals with the least number of deleterious mutations are lost irreversibly…

Populations and Evolution · Quantitative Biology 2013-11-20 Jakob J. Metzger , Stephan Eule

We describe a general strategy, PERM (Pruned-Enriched Rosenbluth Method), for sampling configurations from a given Gibbs-Boltzmann distribution. The method is not based on the Metropolis concept of establishing a Markov process whose…

Soft Condensed Matter · Physics 2007-05-23 P. Grassberger , und H. Frauenkron

For a population with any given number of types, we construct a new multivariate Moran process with frequency-dependent selection and establish, analytically, a correspondence to equilibrium Lotka-Volterra phenomenology. This…

Populations and Evolution · Quantitative Biology 2015-05-30 Andrew E. Noble , Alan Hastings , William F. Fagan

We present an extension of Eigen's model for quasi-species including the competition among individuals, proposed as the simplest mechanism for the formation of new species in a smooth fitness landscape. We are able to obtain analytically…

Statistical Mechanics · Physics 2008-02-03 Franco Bagnoli , Michele Bezzi

We investigate the evolutionary dynamics of a finite population of RNA sequences adapting to a neutral fitness landscape. Despite the lack of differential fitness between viable sequences, we observe typical properties of adaptive…

Populations and Evolution · Quantitative Biology 2007-05-23 Robert Forster , Christoph Adami , Claus O. Wilke

Kingman's model describes the evolution of a one-locus haploid population of infinite size and discrete generations under the competition of selection and mutation. A random generalisation has been made in a previous paper which assumes all…

Probability · Mathematics 2020-12-01 Linglong Yuan

We formulate a general SEIR epidemic model in a heterogenous population characterized by some trait in a discrete or continuous subset of a space R d. The incubation and recovery rates governing the evolution of each homogenous…

Analysis of PDEs · Mathematics 2023-03-03 Luís Almeida , Pierre-Alexandre Bliman , Grégoire Nadin , Benoît Perthame , Nicolas Vauchelet

We show that the Tangled Nature model can be interpreted as a general formulation of the quasi-species model by Eigen et al. in a frequency dependent fitness landscape. We present a detailed theoretical derivation of the mutation threshold,…

Statistical Mechanics · Physics 2009-11-07 Simone Avogadro di Collobiano , Kim Christensen , Henrik Jeldtoft Jensen

The Moran process is a classic stochastic process that models the rise and takeover of novel traits in network-structured populations. In biological terms, a set of mutants, each with fitness $m\in(0,\infty)$ invade a population of…

Data Structures and Algorithms · Computer Science 2024-05-14 Petros Petsinis , Andreas Pavlogiannis , Josef Tkadlec , Panagiotis Karras
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