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Reaction systems are a computational model inspired by the bio-chemical reactions that happen inside biological cells. They have been and currently are studied for their many nice theoretical properties. They are also a useful modeling tool…

Formal Languages and Automata Theory · Computer Science 2020-08-05 Claudio Ferretti , Alberto Leporati , Luca Manzoni , Antonio E. Porreca

The Chemical Reaction Network (CRN) is a well-studied model that describes the interaction of molecules in well-mixed solutions. In 2014, Qian and Winfree [22] proposed the abstract surface chemical reaction network model (sCRN), which…

Computational Complexity · Computer Science 2024-06-14 Yi-Xuan Lee , Ho-Lin Chen

In this article we propose a unified framework in order to study reaction-diffusion systems containing self- and cross-diffusion using a free energy approach. This framework naturally leads to the formulation of an energy law, and to a…

Computational Physics · Physics 2021-10-12 Benjamin Aymard

In this paper, we investigate a mathematical model describing the interactions between effector cells (E), cancer cells (T), and the IL-2 compound (IL). The model considered here is a generalization, taking into account some cross-diffusion…

Dynamical Systems · Mathematics 2025-12-02 C. F. Munafò , S. Bonfiglio , P. Rogolino

The influence of radiation reaction (RR) on multiphoton Thomson scattering by an electron colliding head-on with a strong laser beam is investigated in a new regime, in which the momentum transferred on average to the electron by the laser…

Classical Physics · Physics 2009-07-28 A. Di Piazza , K. Z. Hatsagortsyan , C. H. Keitel

Therapeutic antibody development has become an increasingly popular approach for drug development. To date, antibody therapeutics are largely developed using large scale experimental screens of antibody libraries containing hundreds of…

Quantitative Methods · Quantitative Biology 2022-10-07 Lin Li , Esther Gupta , John Spaeth , Leslie Shing , Tristan Bepler , Rajmonda Sulo Caceres

Mathematical modelling of tumor growth is one of the most useful and inexpensive approaches to determine and predict the stage, size and progression of tumors in realistic geometries. Moreover, these models has been used to get an insight…

Medical Physics · Physics 2017-08-01 Miguel Martín-Landrove

A deployed question answering (QA) model can easily fail when the test data has a distribution shift compared to the training data. Robustness tuning (RT) methods have been widely studied to enhance model robustness against distribution…

Computation and Language · Computer Science 2023-02-10 Hai Ye , Yuyang Ding , Juntao Li , Hwee Tou Ng

We are interested in the problem of multiagent systems development for risk detecting and emergency response in an uncertain and partially perceived environment. The evaluation of the current situation passes by three stages inside the…

Artificial Intelligence · Computer Science 2008-12-18 Fahem Kebair , Frédéric Serin , Cyrille Bertelle

The modelling of linear and nonlinear reaction-subdiffusion processes is more subtle than normal diffusion and causes different phenomena. The resulting equations feature a spatial Laplacian with a temporal memory term through a time…

Analysis of PDEs · Mathematics 2021-08-24 Jichen Yang , Jens D. M. Rademacher

This article reviews the evolving field of radiobiology, emphasizing the need for advanced multiscale, mechanistic models to optimize radiopharmaceutical therapies (RPT). While the traditional linear-quadratic (LQ) model underpins external…

Medical Physics · Physics 2025-09-23 Tahir Yusufaly , Hamid Abdollahi , Babak Saboury , Arman Rahmim

The study of a receptor-ligand system generally relies on the analysis of its dose-response (or concentration-effect) curve, which quantifies the relation between ligand concentration and the biological effect (or cellular response) induced…

Molecular Networks · Quantitative Biology 2022-06-28 Léa Sta , Michael Adamer , Carmen Molina-París

A simple multiscale approach to the diffusion-driven adsorption from a solution to a solid surface is presented. The model combines two important features of the adsorption process: (i) the kinetics of the chemical reaction between…

Chemical Physics · Physics 2009-11-13 Radek Erban , S. Jonathan Chapman

In this paper we consider an optimal control problem arising from a chemotherapeutic drug treatment for tumor cells in a living tissue. The mathematical model for the interaction of chemotherapeutic drug and the normal, tumor and immune…

Analysis of PDEs · Mathematics 2022-12-13 Hong-Ming Yin

Conformational dynamics is crucial for ribonucleic acid (RNA) function. Techniques such as nuclear magnetic resonance, cryo-electron microscopy, small- and wide-angle X-ray scattering, chemical probing, single-molecule F\"orster resonance…

Biomolecules · Quantitative Biology 2025-01-31 Mattia Bernetti , Giovanni Bussi

Experiments are starting to probe collisions and chemical reactions between atoms and molecules at ultra-low temperatures. We have developed a new theoretical procedure for studying these collisions using the R-matrix method. Here this…

Chemical Physics · Physics 2018-10-09 Tom Rivlin , Laura K. McKemmish , Jonathan Tennyson

The pattern of radiation energy deposition in substances at the microscopic level of lattice, molecule size, or the cell's nucleus is not uniform. The energy of radiation is transferred to the substance medium in the form of discrete,…

Medical Physics · Physics 2022-10-14 Elsayed K. Elmaghraby , Mohamed Bahaaeldin-Afifi

We describe a virtual response method and device. It consists of an analog-to-digital converter, a digital-to-analog converter, and a computer and utilizes a searchable response table (RT) pre-stored in the computer to respond to electronic…

Instrumentation and Detectors · Physics 2007-05-23 Jihui Wang , Qingyou Lu , Xuefeng Cui , Bing Wang

The electromagnetic radiation of a rotating relativistic electron layers is studied numerically using particle-in-cell simulation. The results of the simulation confirm all relevant scaling properties predicted by theoretical models. These…

Astrophysics · Physics 2007-05-23 Bjoern S. Schmekel

The thermal resistance associated with the interface between a solid and a liquid is analyzed from an atomistic point of view. Partial evaluation of the associated Green-Kubo integral elucidates the various factors governing heat transport…

Statistical Mechanics · Physics 2022-01-26 Nicolas G. Hadjiconstantinou , Mathew M. Swisher