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We present a new semi-external algorithm that builds the Burrows--Wheeler transform variant of Bauer et al. (a.k.a., BCR BWT) in linear expected time. Our method uses compression techniques to reduce computational costs when the input is…

Data Structures and Algorithms · Computer Science 2023-08-15 Diego Díaz-Domínguez , Gonzalo Navarro

In order to avoid the reference bias introduced by mapping reads to a reference genome, bioinformaticians are investigating reference-free methods for analyzing sequenced genomes. With large projects sequencing thousands of individuals,…

Data Structures and Algorithms · Computer Science 2016-01-15 Jouni Sirén

The Burrows-Wheeler Transform (BWT) is a string transformation technique widely used in areas such as bioinformatics and file compression. Many applications combine a run-length encoding (RLE) with the BWT in a way which preserves the…

Discrete Mathematics · Computer Science 2025-09-18 Lily Major , Amanda Clare , Jacqueline W. Daykin , Benjamin Mora , Christine Zarges

The Burrows-Wheeler transform (BWT) is a well studied text transformation widely used in data compression and text indexing. The BWT of two strings can also provide similarity measures between them, based on the observation that the more…

Data Structures and Algorithms · Computer Science 2020-09-10 Felipe A. Louza , Guilherme P. Telles , Simon Gog , Liang Zhao

The Burrows-Wheeler-Transform (BWT) is an invertible permutation of a text known to be highly compressible but also useful for sequence analysis, what makes the BWT highly attractive for lossless data compression. In this paper, we present…

Data Structures and Algorithms · Computer Science 2018-04-06 Uwe Baier

The Burrows-Wheeler Transform (BWT) is among the most influential discoveries in text compression and DNA storage. It is a reversible preprocessing step that rearranges an $n$-letter string into runs of identical characters (by exploiting…

Data Structures and Algorithms · Computer Science 2018-12-06 Sandip Sinha , Omri Weinstein

Popular sequence alignment tools such as BWA convert a reference genome to an indexing data structure based on the Burrows-Wheeler Transform (BWT), from which matches to individual query sequences can be rapidly determined. However the…

Genomics · Quantitative Biology 2013-04-23 Anthony J. Cox , Tobias Jakobi , Giovanna Rosone , Ole B. Schulz-Trieglaff

The Burrows-Wheeler-Transform (BWT), a reversible string transformation, is one of the fundamental components of many current data structures in string processing. It is central in data compression, as well as in efficient query algorithms…

Data Structures and Algorithms · Computer Science 2024-04-16 Sara Giuliani , Shunsuke Inenaga , Zsuzsanna Lipták , Nicola Prezza , Marinella Sciortino , Anna Toffanello

Introduced about thirty years ago in the field of Data Compression, the Burrows-Wheeler Transform (BWT) is a string transformation that, besides being a booster of the performance of memoryless compressors, plays a fundamental role in the…

Data Structures and Algorithms · Computer Science 2023-05-09 Raffaele Giancarlo , Giovanni Manzini , Antonio Restivo , Giovanna Rosone , Marinella Sciortino

The Burrows-Wheeler Transform (BWT) is a fundamental component in many data structures for text indexing and compression, widely used in areas such as bioinformatics and information retrieval. The extended BWT (eBWT) generalizes the…

Data Structures and Algorithms · Computer Science 2025-06-06 Florian Ingels , Anaïs Denis , Bastien Cazaux

Due to the exponential growth of genomic data, constructing dedicated data structures has become the principal bottleneck in common bioinformatics applications. In particular, the Burrows-Wheeler Transform (BWT) is the basis of some of the…

Data Structures and Algorithms · Computer Science 2023-05-15 Francesco Masillo

The Burrows-Wheeler Transform (BWT) is an invertible text transformation that permutes symbols of a text according to the lexicographical order of its suffixes. BWT is the main component of popular lossless compression programs (such as…

Data Structures and Algorithms · Computer Science 2021-04-13 Dominik Kempa , Tomasz Kociumaka

The Burrows-Wheeler transform (BWT) is a reversible transform that converts a string $w$ into another string $\mathsf{BWT}(w)$. The size of the run-length encoded BWT (RLBWT) can be interpreted as a measure of repetitiveness in the class of…

Discrete Mathematics · Computer Science 2024-11-19 Hideo Bannai , Tomohiro I , Yuto Nakashima

The Burrows-Wheeler Transform (BWT) has been an essential tool in text compression and indexing. First introduced in 1994, it went on to provide the backbone for the first encoding of the classic suffix tree data structure in space close to…

Data Structures and Algorithms · Computer Science 2020-02-19 Jason Bentley , Daniel Gibney , Sharma V. Thankachan

The Burrows-Wheeler Transform (BWT) serves as the basis for many important sequence indexes. On very large datasets (e.g. genomic databases), classical BWT construction algorithms are often infeasible because they usually need to have the…

Data Structures and Algorithms · Computer Science 2025-09-24 Jannik Olbrich

Motivation: High-coverage sequencing data have significant, yet hard to exploit, redundancy. Most FASTQ compressors cannot efficiently compress the DNA stream of large datasets, since the redundancy between overlapping reads cannot be…

Data Structures and Algorithms · Computer Science 2014-09-19 Szymon Grabowski , Sebastian Deorowicz , Łukasz Roguski

The Burrows-Wheeler Transform (BWT) is an efficient invertible text transformation algorithm with the properties of tending to group identical characters together in a run, and enabling search of the text. This transformation has extensive…

Human-Computer Interaction · Computer Science 2024-02-28 Lily Major , Dave Davies , Amanda Clare , Jacqueline W. Daykin , Benjamin Mora , Christine Zarges

The Burrows-Wheeler Transform is a string transformation that plays a fundamental role for the design of self-indexing compressed data structures. Over the years, researchers have successfully extended this transformation outside the…

Data Structures and Algorithms · Computer Science 2019-02-05 Raffaele Giancarlo , Giovanni Manzini , Giovanna Rosone , Marinella Sciortino

The Burrows-Wheeler transform (BWT) is integral to the FM-index, which is used extensively in text compression, indexing, pattern search, and bioinformatic problems as de novo assembly and read alignment. Thus, efficient construction of the…

Data Structures and Algorithms · Computer Science 2025-02-04 Enno Adler , Stefan Böttcher , Rita Hartel , Cederic Alexander Steininger

It is known that the exact form of the Burrows-Wheeler-Transform (BWT) of a string collection depends, in most implementations, on the input order of the strings in the collection. Reordering strings of an input collection affects the…

Data Structures and Algorithms · Computer Science 2022-12-05 Davide Cenzato , Veronica Guerrini , Zsuzsanna Lipták , Giovanna Rosone
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