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Molecular motors play pivotal roles in organizing the interior of cells. A motor efficient in cargo transport would move along cytoskeletal filaments with a high speed and a minimal error in transport distance (or time) while consuming a…

Biological Physics · Physics 2019-06-07 Wonseok Hwang , Changbong Hyeon

Interactions between swimming cells and surfaces are essential to many microbiological processes, from bacterial biofilm formation to human fertilization. However, in spite of their fundamental importance, relatively little is known about…

Biological Physics · Physics 2013-02-04 Vasily Kantsler , Jörn Dunkel , Marco Polin , Raymond E. Goldstein

Clockwise rotational movement of isolated single cilia in mice embryo was investigated in vivo. The movement generates leftward fluid flow in the node cavity and plays an important role in left-right determination. The leftward…

Tissues and Organs · Quantitative Biology 2013-05-22 Atsuko Takamatsu , Takuji Ishikawa , Kyosuke Shinohara , Hiroshi Hamada

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

Biological Physics · Physics 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

Several micro-organisms, such as bacteria, algae, or spermatozoa, use flagella or cilia to swim in a fluid, while many other micro-organisms instead use ample shape deformation, described as amoeboid, to propel themselves by either crawling…

Biological Physics · Physics 2016-09-19 Hao Wu , A. Farutin , W. -F. Hu , M. Thiébaud , S. Rafaï , P. Peyla , M. -C. Lai , C. Misbah

Taking inspiration from the crawling motion of biological cells on a substrate, we consider a physical model of self-propulsion where the spatio-temporal driving can involve both, a mechanical actuation by active force couples, and a…

Soft Condensed Matter · Physics 2024-05-16 Pierre Recho , Lev Truskinovsky

Cilia and flagella are hair-like appendages that protrude from the surface of a variety of eukaryotic cells and deform in a wavelike fashion to transport fluids and propel cells. Motivated by the ubiquity of non-Newtonian fluids in biology,…

Fluid Dynamics · Physics 2014-03-19 J. Rodrigo Vélez-Cordero , Eric Lauga

The motor part of a crawling eukaryotic cell can be represented schematically as an active continuum layer. The main active processes in this layer are protrusion, originating from non-equilibrium polymerization of actin fibers,…

Biological Physics · Physics 2015-01-29 Pierre Recho , Lev Truskinovsky

Ciliary oscillations driven by molecular motors cause fluid motion at micron scale. Stable oscillations require a substantial source of dissipation to balance the energy input of motors. Conventionally, it stems from external fluid. We…

Soft Condensed Matter · Physics 2021-02-23 Debasmita Mondal , Ronojoy Adhikari , Prerna Sharma

Ciliated tissues such as in the mammalian lungs, brains, and reproductive tracts, are specialized to pump fluid. They generate flows by the collective activity of hundreds of thousands of individual cilia that beat in a striking metachronal…

Soft Condensed Matter · Physics 2022-11-30 Anup Kanale , Feng Ling , Hanliang Guo , Sebastian Fuerthauer , Eva Kanso

Enhanced colloidal transport beyond the limit imposed by diffusion is usually achieved through external fields. Here, we demonstrate the ballistic transport of a colloidal sphere using internal sources of energy provided by an attached…

Soft Condensed Matter · Physics 2017-01-12 Raj Kumar Manna , P. B. Sunil Kumar , R. Adhikari

Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling…

Fluid Dynamics · Physics 2018-06-13 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

We study a slender filament beating in a viscous fluid with novel curvature-dependent bending stiffness. Our numerical and experimental investigations reveal that such differential stiffness can sustain planar bending waves far along…

Large groups of active cilia collectively beat in a fluid medium as metachronal waves, essential for some microorganisms motility and for flow generation in mucociliary clearance. Several models can predict the emergence of metachronal…

Soft Condensed Matter · Physics 2024-05-08 Supravat Dey , Gladys Massiera , Estelle Pitard

In this work we mimic the efficient propulsion mechanism of natural cilia by magnetically actuating thin films in a cyclic but non-reciprocating manner. By simultaneously solving the elasto-dynamic, magnetostatic and fluid mechanics…

\emph{Spiroplasma} swimming is studied with a simple model based on resistive-force theory. Specifically, we consider a bacterium shaped in the form of a helix that propagates traveling-wave distortions which flip the handedness of the…

Biological Physics · Physics 2015-05-13 Jing Yang , Charles W. Wolgemuth , Greg Huber

Micro-scale cilia play a vital role in mucociliary clearance (MCC) in the human respiratory airways. In this numerical study, we examine fluid transport driven by the active beating of a single filament immersed in a three-dimensional…

Fluid Dynamics · Physics 2026-02-02 Qian Mao , Umberto d'Ortona , Julien Favier

Cells are modeled with spherical grains connected each other. Each cell can shrink and swell by transporting its fluid content to other connected neighbor while still maintaining its density at constant value. As a spherical part of a cell…

Biological Physics · Physics 2014-02-27 Sparisoma Viridi , Nuning Nuraini

We study a model of cell motility where the condition of optimal trade-off between performance and metabolic cost can be made precise. In this model a steadily crawling fragment is represented by a layer of active gel placed on a frictional…

Biological Physics · Physics 2015-06-18 P. Recho , J. -F. Joanny , L. Truskinovsky

Nature uses elongated shapes and filaments to build stable structures, generate motion, and allow complex geometric interactions. In this Review, we examine the role of biological filaments across different length scales. From the molecular…

Soft Condensed Matter · Physics 2025-07-25 Jan Cammann , Hannah Laeverenz-Schlogelhofer , Kirsty Y. Wan , Marco G. Mazza