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We present proof-of-concept imaging measurements of a polycrystalline material that integrate the elements of conventional high-energy X-ray diffraction microscopy with coherent diffraction imaging techniques, and that can enable in-situ…

Gas phase ultrafast electron diffraction (GUED) has become a powerful technique to directly observe the structural dynamics of photoexcited molecules. GUED reveals information about the nuclear motions that is complementary to the…

A propagation-based x-ray phase-contrast imaging (PBI) setup using a conventional x-ray source (LFF Cu target) is presented. A virtual x-ray source of 40 x 50 $\mu$$m^2$ was created by using, horizontally, a $6^o$ take-off angle (with the…

Other Condensed Matter · Physics 2007-10-08 M. G. Hönnicke , E. M. Kakuno , J. Manica , C. Cusatis

Coherent diffraction imaging (CDI) of single molecules at atomic resolution is a major goal for the x-ray free electron lasers (XFELs). However, during an imaging pulse, the fast laser-induced ionization may strongly affect the recorded…

Mesoscale and Nanoscale Physics · Physics 2015-06-05 Zoltan Jurek , Robert Thiele , Beata Ziaja , Robin Santra

In differential phase contrast scanning transmission electron microscopy (DPC-STEM), variability in dynamical diffraction resulting from changes in sample thickness and local crystal orientation (due to sample bending) can produce contrast…

Materials Science · Physics 2020-02-06 T. Mawson , A. Nakamura , T. C. Petersen , N. Shibata , H. Sasaki , D. M. Paganin , M. J. Morgan , S. D. Findlay

Coherent X-ray diffraction imaging (CXDI) experiments are intrinsically limited by shot noise, a lack of prior knowledge about the sample's support, and missing measurements due to the experimental geometry. We propose a flexible, iterative…

Biological Physics · Physics 2017-03-03 Liang Shi , Gordon Wetzstein , Thomas J. Lane

The ambipolar carrier diffusion in bulk GaAs is studied by using an ultrafast pump-probe technique with a high spatial resolution. Carriers with a point-like spatial profile are excited by a tightly focused pump laser pulse. The…

Materials Science · Physics 2011-02-08 Brian A. Ruzicka , Lalani K. Werake , Hassana Samassekou , Hui Zhao

Structural studies of biological macromolecules are severely limited by radiation damage. Traditional crystallography curbs the effects of damage by spreading damage over many copies of the molecule of interest. X-ray lasers, such as the…

Control of local lattice perturbations near optically-active defects in semiconductors is a key step to harnessing the potential of solid-state qubits for quantum information science and nanoscale sensing. We report the development of a…

Mesoscale and Nanoscale Physics · Physics 2019-07-30 S. J. Whiteley , F. J. Heremans , G. Wolfowicz , D. D. Awschalom , M. V. Holt

Imaging with hard x-rays is an invaluable tool in medicine, biology, materials science, and cultural heritage. Propagation-based x-ray phase-contrast imaging and tomography have been mostly used to resolve micrometer-scale structures inside…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Margie P. Olbinado , David M. Paganin , Yin Cheng , Alexander Rack

Unraveling and controlling chemical dynamics requires techniques to image structural changes of molecules with femtosecond temporal and picometer spatial resolution. Ultrashort-pulse x-ray free-electron lasers have significantly advanced…

Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…

Purpose: Grating-based imaging (GBI) and edge-illumination (EI) are two promising types of XPCI as the conventional x-ray sources can be directly utilized. For GBI and EI systems, the phase-stepping acquisition with multiple exposures at a…

Medical Physics · Physics 2022-01-19 Chengpeng Wu , Yuxiang Xing , Li Zhang , Zhiqiang Chen , Xiaohua Zhu , Xi Zhang , Hewei Gao

Energy-dispersive X-ray diffraction (EDXRD) is extremely insensitive to sample morphology when implemented in a back-reflection geometry. The capabilities of this non-invasive technique for cultural heritage applications have been explored…

Instrumentation and Detectors · Physics 2021-11-19 Craig I. Hiley , Graeme M. Hansford , Nicholas Eastaugh

Cu is an ubiquitous material used in industry for its great thermal and electrical properties. Studying the high-pressure high temperature properties of copper (Cu) is relevant for nuclear fusion research as projectiles and flyers used in…

Flow instabilities such as Haines jumps in porous media are common phenomena that occur on sub-second timescales. X-rays are particularly suitable for investigating these processes because they provide non-destructive three-dimensional…

Measurement modalities in Bragg coherent diffraction imaging (BCDI) rely on finding signal from a single nanoscale crystal object, which satisfies the Bragg condition among a large number of arbitrarily oriented nanocrystals. However, even…

The first-known observation of plasma-induced cavitation bubbles and expanding shockwaves in liquid during plasma initiation timescales reveals deviation from expected Rankine-Hugoniot shock behavior due to coupled shock-cavitation…

A method is proposed for obtaining three simultaneous projections of a target from a single radiation pulse, which also allows the relative orientation of successive targets to be determined. The method has application to femtosecond X-ray…

Soft Condensed Matter · Physics 2009-05-27 K. E. Schmidt , J. C. H. Spence , U. Weierstall , R. Kirian , X. Wang , D. Starodub , H. N. Chapman , M. R. Howells , R. B. Doak

Core level binding energies and absorption edges are at the heart of many experimental techniques concerned with element-specific structure, electronic structure, chemical reactivity, elementary excitations and magnetism. X-ray…