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The paper describes an algorithm to compute a consensus sequence from a set of DNA sequences of approximatively identical length generated by 3rd sequencing generation technologies. Its purpose targets DNA storage and is guided by specific…

Data Structures and Algorithms · Computer Science 2021-05-12 Dominique Lavenier

A framework is introduced for solving a sequence of slowly changing optimization problems, including those arising in regression and classification applications, using optimization algorithms such as stochastic gradient descent (SGD). The…

Machine Learning · Computer Science 2015-09-25 Craig Wilson , Venugopal V. Veeravalli

Applying machine learning to biological sequences - DNA, RNA and protein - has enormous potential to advance human health, environmental sustainability, and fundamental biological understanding. However, many existing machine learning…

Machine Learning · Statistics 2023-04-11 Alan Nawzad Amin , Eli Nathan Weinstein , Debora Susan Marks

Even though deep neural networks have shown tremendous success in countless applications, explaining model behaviour or predictions is an open research problem. In this paper, we address this issue by employing a simple yet effective method…

Computer Vision and Pattern Recognition · Computer Science 2023-01-12 Ryan Benkert , Oluwaseun Joseph Aribido , Ghassan AlRegib

Ambiguity in medical image segmentation calls for models that capture full conditional distributions rather than a single point estimate. We present Prior-Guided Residual Diffusion (PGRD), a diffusion-based framework that learns voxel-wise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Fuyou Mao , Beining Wu , Yanfeng Jiang , Han Xue , Yan Tang , Hao Zhang

Deep neural network-based image classifications are vulnerable to adversarial perturbations. The image classifications can be easily fooled by adding artificial small and imperceptible perturbations to input images. As one of the most…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Jindong Gu , Hengshuang Zhao , Volker Tresp , Philip Torr

DNA segments and sequences have been studied thoroughly during the past decades. One of the main problems in computational biology is the identification of exon-intron structures inside genes using mathematical techniques. Previous studies…

Applications · Statistics 2019-07-09 Pavlos Kolias , Alexandra Papadopoulou

Distributed algorithms for solving coupled semidefinite programs (SDPs) commonly require many iterations to converge. They also put high computational demand on the computational agents. In this paper we show that in case the coupled…

Optimization and Control · Mathematics 2015-04-30 Sina Khoshfetrat Pakazad , Anders Hansson , Martin S. Andersen , Anders Rantzer

The path to interpreting a language model often proceeds via analysis of circuits -- sparse computational subgraphs of the model that capture specific aspects of its behavior. Recent work has automated the task of discovering circuits. Yet,…

Computation and Language · Computer Science 2025-04-03 Adithya Bhaskar , Alexander Wettig , Dan Friedman , Danqi Chen

Deep learning algorithms are increasingly employed at the edge. However, edge devices are resource constrained and thus require efficient deployment of deep neural networks. Pruning methods are a key tool for edge deployment as they can…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Yunqiang Li , Jan C. van Gemert , Torsten Hoefler , Bert Moons , Evangelos Eleftheriou , Bram-Ernst Verhoef

Since the release of human genome sequences, one of the most important research issues is about indexing the genome sequences, and the suffix tree is most widely adopted for that purpose. The traditional suffix tree construction algorithms…

Databases · Computer Science 2015-05-20 Woong-Kee Loh , Yang-Sae Moon , Wookey Lee

To address a looming crisis of unreproducible evaluation for named entity recognition, we propose guidelines and introduce SeqScore, a software package to improve reproducibility. The guidelines we propose are extremely simple and center…

Computation and Language · Computer Science 2021-11-08 Chester Palen-Michel , Nolan Holley , Constantine Lignos

To avoid the exhaustive search over locations and scales, current state-of-the-art object detection systems usually involve a crucial component generating a batch of candidate object proposals from images. In this paper, we present a simple…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Tianshui Chen , Liang Lin , Xian Wu , Nong Xiao , Xiaonan Luo

Time series segmentation aims to identify potential change-points in a sequence of temporally dependent data, so that the original sequence can be partitioned into several homogeneous subsequences. It is useful for modeling and predicting…

Computation · Statistics 2024-04-12 Shubo Sun , Zifeng Zhao , Feiyu Jiang , Xiaofeng Shao

Quantization is commonly used in Deep Neural Networks (DNNs) to reduce the storage and computational complexity by decreasing the arithmetical precision of activations and weights, a.k.a. tensors. Efficient hardware architectures employ…

Machine Learning · Computer Science 2023-11-23 Bahareh Khabbazan , Marc Riera , Antonio González

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

Query Segmentation is one of the critical components for understanding users' search intent in Information Retrieval tasks. It involves grouping tokens in the search query into meaningful phrases which help downstream tasks like search…

Information Retrieval · Computer Science 2017-07-26 Ajinkya Kale , Thrivikrama Taula , Sanjika Hewavitharana , Amit Srivastava

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

MPAgenomics, standing for multi-patients analysis (MPA) of genomic markers, is an R-package devoted to: (i) efficient segmentation, and (ii) genomic marker selection from multi-patient copy number and SNP data profiles. It provides wrappers…

Quantitative Methods · Quantitative Biology 2014-01-21 Quentin Grimonprez , Alain Celisse , Meyling Cheok , Martin Figeac , Guillemette Marot

This paper proposes group-based distributed optimization (DO) algorithms on top of intelligent partitioning for the optimal power flow (OPF) problems. Radial partitioning of the graph of a network is introduced as a systematic way to split…

Optimization and Control · Mathematics 2024-08-07 Mehdi Karimi
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