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Purpose. Radiation therapy is a local treatment aimed at cells in and around a tumor. The goal of this study is to develop an algorithmic solution for predicting the position of a target in 3D in real time, aiming for the short fixed…

Artificial Intelligence · Computer Science 2015-08-05 Tomas Krilavicius , Indre Zliobaite , Henrikas Simonavicius , Laimonas Jarusevicius

Fiducial marker positions in projection image of cone-beam computed tomography (CBCT) scans have been studied to evaluate daily residual motion during breath-hold radiation therapy. Fiducial marker migration posed challenges in accurately…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Aimee Guo , Weihua Mao

Purpose: Implanted fiducial markers are often used in radiotherapy to facilitate accurate visualization and localization of tumors. Typically, such markers are used to aid daily patient positioning and to verify the target's position during…

Medical Physics · Physics 2017-03-14 Warren G. Campbell , Moyed Miften , Bernard L. Jones

During the radiotherapy treatment of patients with lung cancer, the radiation delivered to healthy tissue around the tumor needs to be minimized, which is difficult because of respiratory motion and the latency of linear accelerator…

Image and Video Processing · Electrical Eng. & Systems 2022-07-14 Michel Pohl , Mitsuru Uesaka , Kazuyuki Demachi , Ritu Bhusal Chhatkuli

Lung tumor motion due to respiration poses a challenge in the application of modern three-dimensional conformal radiotherapy. Direct tracking of the lung tumor during radiation therapy is very difficult without implanted fiducial markers.…

Medical Physics · Physics 2015-05-13 Laura I. Cervino , Alvin. K. Y. Chao , Ajay Sandhu , Steve B. Jiang

Lung cancer is the leading cause of cancer-related death worldwide, and early diagnosis is critical to improving patient outcomes. To diagnose cancer, a highly trained pulmonologist must navigate a flexible bronchoscope deep into the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-27 Jake Sganga , David Eng , Chauncey Graetzel , David B. Camarillo

With the advance of imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

Methodology · Statistics 2020-12-10 Qiwei Li , Xinlei Wang , Faming Liang , Guanghua Xiao

In this work, we develop an approach for guiding robots to automatically localize and find the shapes of tumors and other stiff inclusions present in the anatomy. Our approach uses Gaussian processes to model the stiffness distribution and…

We present for the first time a general 6DoF trajectory planning method that can be used in real-time image guided radiation therapy procedures for robotic stabilization of dynamically moving tumor targets. As the radiation beam is always…

Medical Physics · Physics 2018-08-14 Rodney D. Wiersma , Xinmin Liu

Lung cancer is a leading cause of cancer-related deaths worldwide. The spread of the disease from its primary site to other parts of the lungs, known as metastasis, significantly impacts the course of treatment. Early identification of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-18 Teddy Lazebnik , Svetlana Bunimovich-Mendrazitsky

Surgical automation has the potential to enable increased precision and reduce the per-patient workload of overburdened human surgeons. An effective automation system must be able to sense and map subsurface anatomy, such as tumors,…

Robotics · Computer Science 2021-10-13 Brian Y. Cho , Tucker Hermans , Alan Kuntz

This paper focuses on a research problem of robotic controlled laser orientation to minimize errant overcutting of healthy tissue during the course of pathological tissue resection. Laser scalpels have been widely used in surgery to remove…

Robotics · Computer Science 2022-01-06 Guangshen Ma , Weston Ross , Patrick J. Codd

Recently we have developed an algorithm for reconstructing volumetric images and extracting 3D tumor motion information from a single x-ray projection. We have demonstrated its feasibility using a digital respiratory phantom with regular…

Purpose: Analysis of [18F]-Fluorodeoxyglucose (FDG) kinetics in cancer has been most often limited to the evaluation of the average uptake over relatively large volumes. Nevertheless, tumor lesion almost contains inflammatory infiltrates…

Radiation therapy presents a need for dynamic tracking of a target tumor volume. Fiducial markers such as implanted gold seeds have been used to gate radiation delivery but the markers are invasive and gating significantly increases…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Markus D. Foote , Blake E. Zimmerman , Amit Sawant , Sarang Joshi

Lung cancer is the leading cause for cancer related deaths. As such, there is an urgent need for a streamlined process that can allow radiologists to provide diagnosis with greater efficiency and accuracy. A powerful tool to do this is…

Computer Vision and Pattern Recognition · Computer Science 2017-03-29 Devinder Kumar , Mohammad Javad Shafiee , Audrey G. Chung , Farzad Khalvati , Masoom A. Haider , Alexander Wong

Lung tumor tracking for radiotherapy requires real-time, multiple-step ahead forecasting of a quasi-periodic time series recording instantaneous tumor locations. We introduce a location-mixture autoregressive (LMAR) process that admits…

Methodology · Statistics 2014-11-06 Daniel Cervone , Natesh S. Pillai , Debdeep Pati , Ross Berbeco , John Henry Lewis

Purpose: Cone-beam CT (CBCT) projection images provide anatomical data in real-time over several respiratory cycles, forming a comprehensive picture of tumor movement. We developed and validated a method which uses these projections to…

Medical Physics · Physics 2015-01-15 Bernard L. Jones , David Westerly , Moyed Miften

In this paper we present a new method for motion tracking of tumors in liver ultrasound image sequences. Our algorithm has two main steps. In the first step, we apply mean shift algorithm with multiple features to estimate the center of the…

Computer Vision and Pattern Recognition · Computer Science 2015-10-16 Jalil Rasekhi

Radiologists often mix medical image reading strategies, including inspection of individual modalities and local image regions, using information at different locations from different images independently as well as concurrently. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Xiangcen Wu , Shaheer U. Saeed , Yipei Wang , Ester Bonmati Coll , Yipeng Hu
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