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Hierarchies feature prominently in anatomical accounts of cortical organisation. An open question is which computational (algorithmic) processes are implemented by these hierarchies. One renowned hypothesis is that cortical hierarchies…

Neurons and Cognition · Quantitative Biology 2017-09-08 Andreea O. Diaconescu , Vladimir Litvak , Christoph Mathys , Lars Kasper , Karl J. Friston , Klaas E. Stephan

Large scale neural recordings have established that the transformation of sensory stimuli into motor outputs relies on low-dimensional dynamics at the population level, while individual neurons exhibit complex selectivity. Understanding how…

Neurons and Cognition · Quantitative Biology 2018-08-29 Francesca Mastrogiuseppe , Srdjan Ostojic

Chain-of-thought responses from language models improve performance across most benchmarks. However, it remains unclear to what extent these performance gains can be attributed to human-like task decomposition or simply the greater…

Computation and Language · Computer Science 2024-04-25 Jacob Pfau , William Merrill , Samuel R. Bowman

The brain is a highly efficient system evolved to achieve high performance with limited resources. We propose that dendrites make information processing and storage in the brain more efficient through the segregation of inputs and their…

Neurons and Cognition · Quantitative Biology 2023-06-13 Roman Makarov , Michalis Pagkalos , Panayiota Poirazi

The human brain represents the only known example of general intelligence that naturally aligns with human values. On a mere 20-watt power budget, the brain achieves robust learning and adaptive decision-making in ways that continue to…

Neurons and Cognition · Quantitative Biology 2025-08-12 PK Douglas

Axons functionally link the somato-dendritic compartment to synaptic terminals. Structurally and functionally diverse, they accomplish a central role in determining the delays and reliability with which neuronal ensembles communicate. By…

Neurons and Cognition · Quantitative Biology 2019-05-07 Pepe Alcami , Ahmed El Hady

Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…

Neurons and Cognition · Quantitative Biology 2026-01-21 Roxana Zeraati , Anna Levina , Jakob H. Macke , Richard Gao

The brain did not develop a dedicated device for reasoning. This fact bears dramatic consequences. While for perceptuo-motor functions neural activity is shaped by the input's statistical properties, and processing is carried out at high…

Neurons and Cognition · Quantitative Biology 2015-04-21 David Papo

AI's significant recent advances using general-purpose circuit computations offer a potential window into how the neocortex and cerebellum of the brain are able to achieve a diverse range of functions across sensory, cognitive, and motor…

Neurons and Cognition · Quantitative Biology 2024-12-02 Shogo Ohmae , Keiko Ohmae

Neurons, as eukaryotic cells, have powerful internal computation capabilities. One neuron can have many distinct states, and brains can use this capability. Processes of neuron growth and maintenance use chemical signalling between cell…

Neurons and Cognition · Quantitative Biology 2025-12-10 Robert Worden

Our understanding of neural computation is founded on the assumption that neurons fire in response to a linear summation of inputs. Yet experiments demonstrate that some neurons are capable of complex functions that require interactions…

Biological Physics · Physics 2026-03-23 Christopher W. Lynn

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

Neurons and Cognition · Quantitative Biology 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

Neurons and Cognition · Quantitative Biology 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

Providing the neurobiological basis of information processing in higher animals, spiking neural networks must be able to learn a variety of complicated computations, including the generation of appropriate, possibly delayed reactions to…

Neurons and Cognition · Quantitative Biology 2016-06-30 Dominik Thalmeier , Marvin Uhlmann , Hilbert J. Kappen , Raoul-Martin Memmesheimer

The paper introduces a biologically and evolutionarily plausible neural architecture that allows a single group of neurons, or an entire cortical pathway, to be dynamically reconfigured to perform multiple, potentially very different…

Neural and Evolutionary Computing · Computer Science 2015-08-13 Thomas M. Breuel

Computations on the dendritic trees of neurons have important constraints. Voltage dependent conductances in dendrites are not similar to arbitrary direct-current generation, they are the basis for dendritic nonlinearities and they do not…

Neurons and Cognition · Quantitative Biology 2021-08-12 Ilenna Simone Jones , Konrad Paul Kording

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

Mammalian brains span about 4 orders of magnitude in cortical volume and have to operate in different environments that require diverse behavioral skills. Despite these geometric and behavioral diversities, the examination of cerebral…

Neurons and Cognition · Quantitative Biology 2014-05-19 Jan Karbowski

Deep learning has recently led to great successes in tasks such as image recognition (e.g Krizhevsky et al., 2012). However, deep networks are still outmatched by the power and versatility of the brain, perhaps in part due to the richer…

Machine Learning · Statistics 2014-03-25 David P. Reichert , Thomas Serre

The duality of sensory inference and motor control has been known since the 1960s and has recently been recognized as the commonality in computations required for the posterior distributions in Bayesian inference and the value functions in…

Neurons and Cognition · Quantitative Biology 2021-10-12 Kenji Doya
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