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We consider the escape of a flexible, self-avoiding polymer chain out of a confined geometry. By means of simulations, we demonstrate that the translocation time can be described by a simple scaling law that exhibits a nonlinear dependence…

Soft Condensed Matter · Physics 2009-11-11 Angelo Cacciuto , Erik Luijten

We perform molecular dynamics simulations for a simple coarse-grained model of crambin placed inside of a softly repulsive sphere of radius R. The confinement makes folding at the optimal temperature slower and affects the folding…

Biomolecules · Quantitative Biology 2008-12-01 M. Wojciechowski , Marek Cieplak

We examine the effects of confinement on the dynamics of premelted films driven by thermomolecular pressure gradients. Our approach is to modify a well-studied setting in which the thermomolecular pressure gradient is driven by a…

Fluid Dynamics · Physics 2017-11-22 Satyajit Pramanik , John S. Wettlaufer

Recently single molecule experiments have shown the importance of internal friction in biopolymer dynamics. Such studies also suggested that the internal friction although independent of solvent viscosity has strong dependence on denaturant…

Soft Condensed Matter · Physics 2015-06-02 Nairhita Samanta , Rajarshi Chakrabarti

We analyze static properties of a strongly confined semiflexible polymer, i.e. either trapped in a closed space or compressed by external forces, in an athermal solvent. Like a flexible polymer case, we can resort to an analogy with the…

Soft Condensed Matter · Physics 2009-11-13 Takahiro Sakaue

We report on the linear viscoelastic properties of mixtures comprising multiarm star (as model soft colloids) and long linear chain homopolymers in a good solvent. In contrast to earlier works, we investigated symmetric mixtures (with a…

Soft Condensed Matter · Physics 2020-07-01 Daniele Parisi , Domenico Truzzolillo , Vishnu D. Deepak , Mario Gauthier , Dimitris Vlassopoulos

Polymer melts with chains undergoing reversible crosslinking have distinctively favorable dynamic properties, e.g., self healing and reprocessability. In these situations there are two relevant elementary time scales: the segmental and the…

Soft Condensed Matter · Physics 2025-03-14 Rahul Karmakar , Srikanth Sastry , Sanat K. Kumar , Tarak K. Patra

Using molecular dynamics simulations we examine the dynamics of a family of model polymers with varying chain length and torsional potential barriers. We focus on features of the dynamics of polymers that are seen experimentally but absent…

Soft Condensed Matter · Physics 2019-06-11 Daniel Fragiadakis , C. Michael Roland

We investigate theoretically the physics of diffusion-limited intramolecular polymer reactions. The present work completes and goes beyond a previous study [Nat. Chem. 4, 268 (2012)] that showed that the distribution of the polymer…

Statistical Mechanics · Physics 2015-06-12 T. Guérin , O. Bénichou , R. Voituriez

Polymer models describing the statistics of biomolecules under confinement have applications to a wide range of single molecule experimental techniques and give insight into biologically relevant processes {\em{in vivo}}. In this paper, we…

Biological Physics · Physics 2023-09-18 Joel Gard , Greg Morrison

During the life cycle of bacterial cells the non-mixing of the two ring-shaped daughter genomes is an important prerequisite for the cell division process. Mimicking the environments inside highly crowded biological cells, we study the…

Soft Condensed Matter · Physics 2014-12-24 Jaeoh Shin , Andrey G Cherstvy , Ralf Metzler

We investigate the microtubule polymerization dynamics with catastrophe and rescue events for three different confinement scenarios, which mimic typical cellular environments: (i) The microtubule is confined by rigid and fixed walls, (ii)…

Subcellular Processes · Quantitative Biology 2015-05-12 Björn Zelinski , Nina Müller , Jan Kierfeld

We develop topological methods for characterizing the relationship between polymer chain entanglement and bulk viscoelastic responses. We introduce generalized Linking Number and Writhe characteristics that are applicable to open linear…

Soft Condensed Matter · Physics 2023-02-28 Eleni Panagiotou , Ken Millett , Paul J. Atzberger

We study theoretically the velocity cross-correlations of a viscous fluid confined in a slit between two viscoelastic media. We analyze the effect of these correlations on the motions of particles suspended in the fluid. The compliance of…

Soft Condensed Matter · Physics 2017-09-14 Chen Bar-Haim , Haim Diamant

We use linear stability analysis and hybrid lattice Boltzmann simulations to study the dynamical behaviour of an active nematic confined in a channel made of viscoelastic material. We find that the quiescent, ordered active nematic is…

Soft Condensed Matter · Physics 2023-12-20 Francesco Mori , Saraswat Bhattacharyya , Julia M. Yeomans , Sumesh P. Thampi

We investigate the conformational and dynamical properties of a partially active Rouse chain, where activity is localized within a specific segment, positioned at various locations along the chain and spanning any given length. Through…

Soft Condensed Matter · Physics 2024-12-06 Koushik Goswami , Norman Hsia , Cheng-Hung Chang , Hong-Yan Shih

A number of recent experiments have provided detailed observations of the configurations of long DNA strands under nano-to-micrometer sized confinement. We therefore revisit the problem of an excluded volume polymer chain confined between…

Soft Condensed Matter · Physics 2011-03-23 Debasish Chaudhuri , Bela Mulder

We study the conformations of a semiflexible chain, confined in nano-scaled spherical cavities, under two distinct processes of confinement. Radial contraction and packaging are employed as two confining procedures. The former method is…

Soft Condensed Matter · Physics 2014-09-29 Arman Fathizadeh , Maziar Heidari , Behrouz Eslami-Mossallam , Mohammad Reza Ejtehadi

We present results from molecular dynamics simulations of strictly two-dimensional (2D) polymer melts and thin polymer films in a slit geometry of thickness of the order of the radius of gyration. We find that the dynamics of the 2D melt is…

Soft Condensed Matter · Physics 2007-05-23 H. Meyer , T. Kreer , A. Cavallo , J. P. Wittmer , J. Baschnagel

Despite the extensive research that has been conducted for decades on the behavior of confined liquids, detailed knowledge of this phenomenon, particularly in the mixed/boundary lubrication regime, remains limited. This can be attributed to…

Soft Condensed Matter · Physics 2022-10-05 Yusei Kobayashi , Noriyoshi Arai , Kenji Yasuoka