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We introduce a practical hybrid approach that combines orbital-free density functional theory (DFT) with Kohn-Sham DFT for speeding up first-principles molecular dynamics simulations. Equilibrated ionic configurations are generated using…

Peridynamic (PD) theory is significant and promising in engineering and materials science; however, it imposes challenges owing to the enormous computational cost caused by its nonlocality. Our main contribution, which overcomes the…

Numerical Analysis · Mathematics 2023-01-30 Chenguang Liu , Hao Tian , Wai sun Don , Hong Wang

We introduce a combined molecular dynamics (MD) and quantum trajectories (QT) code to simulate the effects of near-resonant optical fields on state-vector evolution and particle motion in a collisional system. In contrast to collisionless…

Atomic Physics · Physics 2020-02-05 G. M. Gorman , T. K. Langin , M. K. Warrens , D. Vrinceanu , T. C. Killian

In this work, we present a quantum algorithm for direct first-principles simulation of electron-nuclear dynamics on a first-quantized real-space grid. Our algorithm achieves best-in-class efficiency for block-encoding the…

Quantum Physics · Physics 2026-02-13 Matthew Pocrnic , Ignacio Loaiza , Juan Miguel Arrazola , Nathan Wiebe , Danial Motlagh

We present an efficient quantum algorithm for beyond-Born-Oppenheimer molecular energy computations. Our approach combines the quantum full configuration interaction method with the nuclear orbital plus molecular orbital (NOMO) method. We…

Quantum Physics · Physics 2016-02-24 Libor Veis , Jakub Višňák , Hiroaki Nishizawa , Hiromi Nakai , Jiří Pittner

While most work on the quantum simulation of chemistry has focused on computing energy surfaces, a similarly important application requiring subtly different algorithms is the computation of energy derivatives. Almost all molecular…

We present an improved field-theoretic approach to the grand-canonical potential suitable for linear scaling molecular dynamics simulations using forces from self-consistent electronic structure calculations. It is based on an exact…

Computational Physics · Physics 2014-06-23 Dorothee Richters , Thomas D. Kühne

The coarse-grained molecular dynamics (MD) or Brownian dynamics (BD) simulation is a particle-based approach that has been applied to a wide range of biological problems that involve interactions with surrounding fluid molecules or the…

Soft Condensed Matter · Physics 2014-11-20 Szu-Pei Fu , Yuan-Nan Young , Shidong Jiang

We present a novel approach to investigate the long-time stochastic dynamics of multi-dimensional classical systems, in contact with a heat-bath. When the potential energy landscape is rugged, the kinetics displays a decoupling of short and…

Soft Condensed Matter · Physics 2013-05-29 O. Corradini , P. Faccioli , H. Orland

Simulating atomic-scale processes, such as protein dynamics and catalytic reactions, is crucial for advancements in biology, chemistry, and materials science. Machine learning force fields (MLFFs) have emerged as powerful tools that achieve…

Chemical Physics · Physics 2024-12-30 Lars L. Schaaf , Ilyes Batatia , Christoph Brunken , Thomas D. Barrett , Jules Tilly

Simulating noninteracting fermion systems is a common task in computational many-body physics. In absence of translational symmetries, modeling free fermions on $N$ modes usually requires poly$(N)$ computational resources. While often…

Quantum Physics · Physics 2026-02-24 Maarten Stroeks , Daan Lenterman , Barbara Terhal , Yaroslav Herasymenko

A simple and efficient algorithm of the molecular-dynamics simulation of the hard disk system based on the Event-Driven method is developed. From the analysis of algorithm, the complexity is O(log N) per 1 event, and the constant…

Computational Physics · Physics 2009-10-31 Masaharu Isobe

Molecular dynamics (MD) simulates the time evolution of atomic systems governed by interatomic forces, and the fidelity of these simulations depends critically on the underlying force model. Classical force fields (CFFs) rely on fixed…

Performance · Computer Science 2026-03-05 Udari De Alwis , Benjamin E. Mayer , Tom J. Ashby , Maria Barrera , Timon Evenblij , Joyjit Kundu

The evolution of molecular dynamics (MD) simulations has been intimately linked to that of computing hardware. For decades following the creation of MD, simulations have improved with computing power along the three principal dimensions of…

For nearly the past 30 years, Centroid Molecular Dynamics (CMD) has proven to be a viable classical-like phase space formulation for the calculation of quantum dynamical properties. However, calculation of the centroid effective force…

Chemical Physics · Physics 2022-09-15 Timothy D. Loose , Patrick G. Sahrmann , Gregory A. Voth

An approximate approach to quantum vibrational dynamics, "Brownian Chain Molecular Dynamics (BCMD)", is proposed to alleviate the chain resonance and curvature problems in the imaginary time-based path integral (PI) simulation. Here the…

Chemical Physics · Physics 2024-01-26 Motoyuki Shiga

Graph-based linear scaling electronic structure theory for quantum-mechanical molecular dynamics simulations is adapted to the most recent shadow potential formulations of extended Lagrangian Born-Oppenheimer molecular dynamics, including…

Chemical Physics · Physics 2023-03-08 Christian F. A. Negre , Michael E. Wall , Anders M. N. Niklasson

Continuous-time stochastic processes pervade everyday experience, and the simulation of models of these processes is of great utility. Classical models of systems operating in continuous-time must typically track an unbounded amount of…

Quantum Physics · Physics 2018-03-05 Thomas J. Elliott , Mile Gu

All-atom and coarse-grained molecular dynamics are two widely used computational tools to study the conformational states of proteins. Yet, these two simulation methods suffer from the fact that without access to supercomputing resources,…

Quantitative Methods · Quantitative Biology 2022-06-13 Gregory Schwing , Luigi L. Palese , Ariel Fernández , Loren Schwiebert , Domenico L. Gatti

Molecular dynamics (MD) is an important research tool extensively applied in materials science. Running MD on a graphics processing unit (GPU) is an attractive new approach for accelerating MD simulations. Currently, GPU implementations of…

Computational Physics · Physics 2015-06-12 Qing Hou , Min Li , Yulu Zhou , Jiechao Cui , Zhenguo Cui , Jun Wang
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