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An increasing number of models require the control of the spectral norm of convolutional layers of a neural network. While there is an abundance of methods for estimating and enforcing upper bounds on those during training, they are…
The high throughput and cost-effectiveness afforded by short-read sequencing technologies, in principle, enable researchers to perform 16S rRNA profiling of complex microbial communities at unprecedented depth and resolution. Existing…
Large annotated datasets are crucial for the success of deep neural networks, but labeling data can be prohibitively expensive in domains such as medical imaging. This work tackles the subset selection problem: selecting a small set of the…
The choice of crossover and mutation strategies plays a crucial role in the searchability, convergence efficiency and precision of genetic algorithms. In this paper, a novel improved genetic algorithm is proposed by improving the crossover…
We systematically explored a spectrum of normalization algorithms related to Batch Normalization (BN) and propose a generalized formulation that simultaneously solves two major limitations of BN: (1) online learning and (2) recurrent…
The standard approach to tackling computer vision problems is to train deep convolutional neural network (CNN) models using large-scale image datasets which are representative of the target task. However, in many scenarios, it is often…
In modern large-scale machine learning applications, the training data are often partitioned and stored on multiple machines. It is customary to employ the "data parallelism" approach, where the aggregated training loss is minimized without…
Driven by large data trained segmentation models, such as SAM , research in one-shot segmentation has experienced significant advancements. Recent contributions like PerSAM and MATCHER , presented at ICLR 2024, utilize a similar approach by…
Limited data and low dose constraints are common problems in a variety of tomographic reconstruction paradigms which lead to noisy and incomplete data. Over the past few years sinogram denoising has become an essential pre-processing step…
Computational analysis methods including machine learning have a significant impact in the fields of genomics and medicine. High-throughput gene expression analysis methods such as microarray technology and RNA sequencing produce enormous…
Solving image classification tasks given small training datasets remains an open challenge for modern computer vision. Aggressive data augmentation and generative models are among the most straightforward approaches to overcoming the lack…
Deep learning based image segmentation has achieved the state-of-the-art performance in many medical applications such as lesion quantification, organ detection, etc. However, most of the methods rely on supervised learning, which require a…
Rapid sequencing of individual human genome is prerequisite to genomic medicine, where diseases will be prevented by preemptive cures. Quantum-mechanical tunneling through single-stranded DNA in a solid-state nanopore has been proposed for…
Since the arrival of next-generation sequencing technologies the amount of genetic sequencing data has increased dramatically. This has has fueled an increase in human genetics research. At the same time, with the recent advent of…
Data augmentation is an effective and universal technique for improving generalization performance of deep neural networks. It could enrich diversity of training samples that is essential in medical image segmentation tasks because 1) the…
One of the most computationally intensive tasks in computational biology is de novo genome assembly, the decoding of the sequence of an unknown genome from redundant and erroneous short sequences. A common assembly paradigm identifies…
We have devised a simple numerical technique to treat rugged data points that arise due to the insufficient gain setting error (or quantization error) of a digital instrument. This is a very wide spread problem that all experimentalists…
Recently deep learning methods, in particular, convolutional neural networks (CNNs), have led to a massive breakthrough in the range of computer vision. Also, the large-scale annotated dataset is the essential key to a successful training…
Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…
Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…