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We present a systematic study of the influence of cell geometry on the orientational distribution of microtubules (MTs) nucleated from a single microtubule organizing center (MTOC). For simplicity we consider an elliptical cell geometry, a…

Biomolecules · Quantitative Biology 2022-11-30 Panayiotis Foteinopoulos , Bela M. Mulder

Recent work suggests goal-driven training of neural networks can be used to model neural activity in the brain. While response properties of neurons in artificial neural networks bear similarities to those in the brain, the network…

Neurons and Cognition · Quantitative Biology 2020-05-19 Christopher J. Cueva , Peter Y. Wang , Matthew Chin , Xue-Xin Wei

Street networks may be planned according to clear organizing principles or they may evolve organically through accretion, but their configurations and orientations help define a city's spatial logic and order. Measures of entropy reveal a…

Physics and Society · Physics 2019-08-20 Geoff Boeing

Since gyri and sulci, two basic anatomical building blocks of cortical folding patterns, were suggested to bear different functional roles, a precise mapping from brain function to gyro-sulcal patterns can provide profound insights into…

Neurons and Cognition · Quantitative Biology 2022-05-24 Li Yang , Zhibin He , Changhe Li , Junwei Han , Dajiang Zhu , Tianming Liu , Tuo Zhang

In this work, we tackle the problem of modeling the vehicle environment as dynamic occupancy grid map in complex urban scenarios using recurrent neural networks. Dynamic occupancy grid maps represent the scene in a bird's eye view, where…

Robotics · Computer Science 2022-05-06 Marcel Schreiber , Vasileios Belagiannis , Claudius Glaeser , Klaus Dietmayer

Research on network mechanisms and coding properties of grid cells assume that the firing rate of a grid cell in each of its fields is the same. Furthermore, proposed network models predict spatial regularities in the firing of inhibitory…

Neurons and Cognition · Quantitative Biology 2017-01-19 Benjamin Dunn , Daniel Wennberg , Ziwei Huang , Yasser Roudi

Understanding spatial location and relationships is a fundamental capability for modern artificial intelligence systems. Insights from human spatial cognition provide valuable guidance in this domain. Neuroscientific discoveries have…

Neural and Evolutionary Computing · Computer Science 2024-09-17 Boyang Li , Yulin Wu , Nuoxian Huang , Wenjia Zhang

Grid cells play a principal role in enabling mammalian cognitive representations of ambient environments. The key property of these cells -- the regular arrangement of their firing fields -- is commonly viewed as means for establishing…

Neurons and Cognition · Quantitative Biology 2022-08-30 Yuri Dabaghian

Grid cells recorded in the parahippocampal formation of freely moving rodents provide a strikingly periodic representation of self-location whose underlying mechanism has been the subject of intense interest. Our previous work(1) showed…

Neurons and Cognition · Quantitative Biology 2015-12-22 Julija Krupic , Neil Burgess , John O'Keefe

The hippocampal formation is thought to learn spatial maps of environments, and in many models this learning process consists of forming a sensory association for each location in the environment. This is inefficient, akin to learning a…

Artificial Intelligence · Computer Science 2021-07-02 Marcus Lewis

Artificial and biological agents cannon learn given completely random and unstructured data. The structure of data is encoded in the metric relationships between data points. In the context of neural networks, neuronal activity within a…

Machine Learning · Computer Science 2022-11-03 Kosio Beshkov , Jonas Verhellen , Mikkel Elle Lepperød

In this work we investigate the environmental dependence of the intrinsic ellipticity correlations in cosmic shear surveys. We use the quadratic and linear alignment model to describe the contributions by spiral and elliptical galaxies,…

Cosmology and Nongalactic Astrophysics · Physics 2019-08-05 Robert Reischke , Björn Malte Schäfer

Robotic and animal mapping systems share many of the same objectives and challenges, but differ in one key aspect: where much of the research in robotic mapping has focused on solving the data association problem, the grid cell neurons…

Computer Vision and Pattern Recognition · Computer Science 2018-10-24 Huu Le , Michael Milford

Occupancy grids are the most common framework when it comes to creating a map of the environment using a robot. This paper studies occupancy grids from the motion planning perspective and proposes a mapping method that provides richer data…

Robotics · Computer Science 2016-09-20 Ali-akbar Agha-mohammadi

The primary visual cortex of many mammals contains a continuous representation of visual space, with a roughly repetitive aperiodic map of orientation preferences superimposed. It was recently found that orientation preference maps (OPMs)…

Neurons and Cognition · Quantitative Biology 2015-03-19 Wolfgang Keil , Fred Wolf

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Neurons and Cognition · Quantitative Biology 2021-02-03 J. Mendoza-Ruiz , C. E. Alonso-Malaver , M. Valderrama , O. A. Rosso , J. H. Martínez

For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…

Biological Physics · Physics 2020-04-03 Lucas da Costa Campos , Raphael Hornung , Gerhard Gompper , Jens Elgeti , Svenja Caspers

A multi-layer perceptron (MLP) is a type of neural networks which has a long history of research and has been studied actively recently in computer vision and graphics fields. One of the well-known problems of an MLP is the capability of…

Graphics · Computer Science 2023-10-31 Shin Fujieda , Atsushi Yoshimura , Takahiro Harada

Collective response to external directional cues like electric fields plays a pivotal role in processes such as tissue development, regeneration, and wound healing. In this study we focus on the impact of anisotropy in cell shape and local…

Cell Behavior · Quantitative Biology 2024-04-09 Kurmanbek Kaiyrbekov , Brian A. Camley

Since their Nobel Prize winning discovery in 2005, grid cells have been studied extensively by neuroscientists. Their multi-scale periodic firing rates tiling the environment as the animal moves around has been shown as critical for path…

Neurons and Cognition · Quantitative Biology 2022-10-24 Jason Toy