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Living systems are capable of locomotion, reconfiguration, and replication. To perform these tasks, cells spatiotemporally coordinate the interactions of force-generating, "active" molecules that create and manipulate non-equilibrium…

Soft Condensed Matter · Physics 2019-08-28 Tyler D. Ross , Heun Jin Lee , Zijie Qu , Rachel A. Banks , Rob Phillips , Matt Thomson

We report the simultaneous characterization of time- and force-dependent mechanical properties of adherent cells in the physiologically relevant regime of large forces. We used magnetic tweezers to apply forces to magnetic beads bound to…

Biological Physics · Physics 2010-02-02 Philip Kollmannsberger , Claudia T. Mierke , Ben Fabry

The fluctuation-dissipation relation (FDR) links thermal fluctuations and dissipation at thermal equilibrium through temperature. Extending it beyond equilibrium conditions in pursuit of broadening thermodynamics is often feasible, albeit…

Statistical Mechanics · Physics 2025-02-04 Dima Boriskovsky , Benjamin Lindner , Yael Roichman

Recent works have reported on the collective behavior of multiphase systems under fractional flow. Such behavior has been linked to pressure and/or flux fluctuations under stationary flow conditions that occur over a broad range of…

Fluid Dynamics · Physics 2025-02-18 Dick Bedeaux , Signe Kjelstrup , Steffen Berg , Umar Alfazazi , Ryan T. Armstrong

We investigate excluded-volume effects in a bidisperse colloidal suspension near a flexible interface. Inspired by a recent experiment by Dinsmore et al. (Phys. Rev, Lett. 80, 409 (1998)), we study the adsorption of a mesoscopic bead on the…

Soft Condensed Matter · Physics 2009-11-10 Thomas Bickel

Static nonreciprocal forces between particles generically drive persistent motion reminiscent of self-propulsion. Here, we demonstrate that reciprocity-breaking fluctuations about a reciprocal mean coupling strength are sufficient to…

Soft Condensed Matter · Physics 2023-04-18 Luca Cocconi , Henry Alston , Thibault Bertrand

The effect of a change of noise amplitudes in overdamped diffusive systems is linked to their unperturbed behavior by means of a nonequilibrium fluctuation-response relation. This formula holds also for systems with state-independent…

Statistical Mechanics · Physics 2017-06-13 Cem Yolcu , Antoine Bérut , Gianmaria Falasco , Artyom Petrosyan , Sergio Ciliberto , Marco Baiesi

We review generalized Fluctuation-Dissipation Relations which are valid under general conditions even in ``non-standard systems'', e.g. out of equilibrium and/or without a Hamiltonian structure. The response functions can be expressed in…

Statistical Mechanics · Physics 2019-09-10 A. Sarracino , A. Vulpiani

In the paper the rescaled occupation time fluctuation process of a certain empirical system is investigated. The system consists of particles evolving independently according to \alpha-stable motion in R^d, \alpha<d<2\alpha. The particles…

Probability · Mathematics 2011-09-02 Piotr Milos

The inference of causal relationships among observed variables is a pivotal, longstanding problem in the scientific community. An intuitive method for quantifying these causal links involves examining the response of one variable to…

Statistical Mechanics · Physics 2025-03-27 Gabriele Di Antonio , Gianni Valerio Vinci

Fluctuation relations are derived in systems where the spin degree of freedom and magnetic interactions play a crucial role. The form of the non-equilibrium fluctuation theorems relies in the assumption of a local balance condition. We…

Mesoscale and Nanoscale Physics · Physics 2012-06-21 Rosa Lopez , Jong Soo Lim , David Sanchez

The underdamped, non-linear, generalized Langevin equation is widely used to model coarse-grained dynamics of soft and biological materials. By means of a projection operator formalism, we show under which approximations this equation can…

Soft Condensed Matter · Physics 2022-02-04 Fabian Glatzel , Tanja Schilling

We consider the dynamics of the disordered trap model, which is known to be completely out-of-equilibrium and to present strong localization effects in its aging phase. We are interested into the influence of an external force, when it is…

Condensed Matter · Physics 2009-11-10 Cecile Monthus

The fluctuation-dissipation theorem is a cornerstone result in statistical mechanics that can be used to translate the statistics of the free natural variability of a system into information on its forced response to perturbations. By…

Statistical Mechanics · Physics 2025-06-19 Niccolò Zagli , Matthew Colbrook , Valerio Lucarini , Igor Mezić , John Moroney

The production of mechanical stresses in living organisms largely relies on localized, force-generating active units embedded in filamentous matrices. Numerical simulations of discrete fiber networks with fixed boundaries have shown that…

Biological Physics · Physics 2018-05-10 Pierre Ronceray , Chase Broedersz , Martin Lenz

We present a derivation of a recently proposed theory for the time dependence of density fluctuations in stationary states of strongly interacting, athermal, self-propelled particles. The derivation consists of two steps. First, we start…

Soft Condensed Matter · Physics 2016-01-13 Grzegorz Szamel

We experimentally determine the force exerted by a bath of active particles onto a passive probe as a function of its distance to a wall and compare it to the measured averaged density distribution of active particles around the probe.…

Soft Condensed Matter · Physics 2022-08-10 Shuvojit Paul , Ashreya Jayaram , N Narinder , Thomas Speck , Clemens Bechinger

We calculate the fluctuation spectrum of the shape of a lipid vesicle or cell exposed to a nonthermal source of noise. In particular we take into account constraints on the membrane area and the volume of fluid that it encapsulates when…

Soft Condensed Matter · Physics 2013-11-07 Bastien Loubet , Udo Seifert , Michael Andersen Lomholt

Synaptic connections in neuronal circuits are modulated by pre- and post-synaptic spiking activity. Heuristic models of this process of synaptic plasticity can provide excellent fits to results from in-vitro experiments in which pre- and…

Neurons and Cognition · Quantitative Biology 2022-07-14 Federico Devalle , Alex Roxin

We report new experimental results obtained onthe insulating spin glass CdCrInS_4. Our experimental setup allows a quantitative comparison between thethermo-remanent magnetization and the autocorrelation of spontaneous fluctuations of…

Disordered Systems and Neural Networks · Physics 2009-11-10 Didier Herisson , Miguel Ocio
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