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Correlation among the observations in high-dimensional regression modeling can be a major source of confounding. We present a new open-source package, plmmr, to implement penalized linear mixed models in R. This R package estimates…

Computation · Statistics 2026-05-13 Tabitha K. Peter , Anna C. Reisetter , Yujing Lu , Oscar A. Rysavy , Patrick J. Breheny

Independence screening is a variable selection method that uses a ranking criterion to select significant variables, particularly for statistical models with nonpolynomial dimensionality or "large p, small n" paradigms when p can be as…

Methodology · Statistics 2012-10-18 Gaorong Li , Heng Peng , Jun Zhang , Lixing Zhu

In the field of big data analytics, the search for efficient subdata selection methods that enable robust statistical inferences with minimal computational resources is of high importance. A procedure prior to subdata selection could…

Methodology · Statistics 2024-11-12 Vasilis Chasiotis , Lin Wang , Dimitris Karlis

Motivated by applications in neuroanatomy, we propose a novel methodology for estimating the heritability which corresponds to the proportion of phenotypic variance which can be explained by genetic factors. Estimating this quantity for…

Statistics Theory · Mathematics 2016-06-09 Anna Bonnet , Céline Lévy-Leduc , Elisabeth Gassiat , Roberto Toro , Thomas Bourgeron

We introduce a Bayesian framework for mixed-type multivariate regression using continuous shrinkage priors. Our framework enables joint analysis of mixed continuous and discrete outcomes and facilitates variable selection from the $p$…

Statistics Theory · Mathematics 2024-12-20 Shao-Hsuan Wang , Ray Bai , Hsin-Hsiung Huang

Non-negative Matrix Factorization (NMF) is a useful method to extract features from multivariate data, but an important and sometimes neglected concern is that NMF can result in non-unique solutions. Often, there exist a Set of Feasible…

Applications · Statistics 2021-01-20 Ragnhild Laursen , Asger Hobolth

Most machine learning and deep neural network algorithms rely on certain iterative algorithms to optimise their utility/cost functions, e.g. Stochastic Gradient Descent. In distributed learning, the networked nodes have to work…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-06 Liang Wang , Ben Catterall , Richard Mortier

Genome-wide association studies have proven to be essential for understanding the genetic basis of disease. However, many complex traits---personality traits, facial features, disease subtyping---are inherently high-dimensional, impeding…

Applications · Statistics 2015-12-09 Ashlee Valente , Geoffrey Ginsburg , Barbara E Engelhardt

Missing values are a common problem in data science and machine learning. Removing instances with missing values can adversely affect the quality of further data analysis. This is exacerbated when there are relatively many more features…

Machine Learning · Computer Science 2023-01-03 Ekaterina Antonenko , Jesse Read

In genetic studies, not only can the number of predictors obtained from microarray measurements be extremely large, there can also be multiple response variables. Motivated by such a situation, we consider semiparametric dimension reduction…

Methodology · Statistics 2013-09-25 Heng Lian , Shujie Ma

Covariance matrix estimation is a fundamental statistical task in many applications, but the sample covariance matrix is sub-optimal when the sample size is comparable to or less than the number of features. Such high-dimensional settings…

Methodology · Statistics 2022-06-06 Huiqin Xin , Sihai Dave Zhao

In high-dimensional data settings where $p\gg n$, many penalized regularization approaches were studied for simultaneous variable selection and estimation. However, with the existence of covariates with weak effect, many existing variable…

Methodology · Statistics 2016-03-24 Xiaoli Gao , S. E. Ahmed , Yang Feng

Intracortical brain-machine interfaces demand low-latency, energy-efficient solutions for neural decoding. Spiking Neural Networks (SNNs) deployed on neuromorphic hardware have demonstrated remarkable efficiency in neural decoding by…

Neural and Evolutionary Computing · Computer Science 2025-04-17 Francesca Rivelli , Martin Popov , Charalampos S. Kouzinopoulos , Guangzhi Tang

The sparse generalized eigenvalue problem arises in a number of standard and modern statistical learning models, including sparse principal component analysis, sparse Fisher discriminant analysis, and sparse canonical correlation analysis.…

Numerical Analysis · Computer Science 2019-03-05 Ganzhao Yuan , Li Shen , Wei-Shi Zheng

Traditional variable selection methods could fail to be sign consistent when irrepresentable conditions are violated. This is especially critical in high-dimensional settings when the number of predictors exceeds the sample size. In this…

Methodology · Statistics 2022-04-26 Fei Xue , Annie Qu

In recent years the importance of finding a meaningful pattern from huge datasets has become more challenging. Data miners try to adopt innovative methods to face this problem by applying feature selection methods. In this paper we propose…

Machine Learning · Computer Science 2014-03-11 Mehdi Naseriparsa , Amir-masoud Bidgoli , Touraj Varaee

Stochastic First-Order (SFO) methods have been a cornerstone in addressing a broad spectrum of modern machine learning (ML) challenges. However, their efficacy is increasingly questioned, especially in large-scale applications where…

Machine Learning · Computer Science 2024-08-01 Di Zhang , Suvrajeet Sen

Causal effect estimation is a critical task in statistical learning that aims to find the causal effect on subjects by identifying causal links between a number of predictor (or, explanatory) variables and the outcome of a treatment. In a…

Methodology · Statistics 2024-11-26 Tathagata Basu , Matthias C. M. Troffaes

This article presents a novel method for causal discovery with generalized structural equation models suited for analyzing diverse types of outcomes, including discrete, continuous, and mixed data. Causal discovery often faces challenges…

Methodology · Statistics 2023-10-26 Minjie Wang , Xiaotong Shen , Wei Pan

There are several existing algorithms that under appropriate assumptions can reliably identify a subset of the underlying causal relationships from observational data. This paper introduces the first computationally feasible score-based…

Artificial Intelligence · Computer Science 2012-07-02 Subramani Mani , Peter L. Spirtes , Gregory F. Cooper