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The relation between a structure and the function running on that structure is of central interest in many fields, including computer science, biology (organ vs. function), psychology (body vs. mind), architecture (designs vs.…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-16 Ciprian Ionut Paduraru , Gheorghe Stefanescu

The idea of a systematic digital representation of the entire known human pathophysiology, which we could call the Virtual Human Twin, has been around for decades. To date, most research groups focused instead on developing highly…

Medical Physics · Physics 2023-08-15 Marco Viceconti , Maarten De Vos , Sabato Mellone , Liesbet Geris

Cloud computing has been shown to be an essential enabling technology for public sector organizations PSOs and offers numerous potential benefits, including reduced information technology infrastructure costs, increased innovation…

Computers and Society · Computer Science 2026-01-13 Mark Theby

As testified by new regulations like the European AI act, the worries about the societal impact of (autonomous) software technologies are becoming of public concern. Social and human values, besides the traditional software behaviour and…

Software Engineering · Computer Science 2024-06-14 Martina De Sanctis , Paola Inverardi , Patrizio Pelliccione

Major depressive disorder is a debilitating disease affecting 264 million people worldwide. While many antidepressant medications are available, few clinical guidelines support choosing among them. Decision support tools (DSTs) embodying…

Reproducibility should be a cornerstone of science as it enables validation and reuse. In recent years, the scientific community and the general public became increasingly aware of the reproducibility crisis, i.e. the wide-spread inability…

Human-Computer Interaction · Computer Science 2020-12-07 Sebastian Stefan Feger

Peer support is critical to managing chronic health conditions. Online health communities (OHCs) enable patients and caregivers to connect with similar others, yet their large scale makes it challenging to find the most relevant peers and…

Human-Computer Interaction · Computer Science 2026-03-13 Pronob Kumar Barman , James R. Foulds , Tera L. Reynolds

The Berkeley Open Infrastructure for Network Computing (BOINC) is an open source client-server middleware system created to allow projects with large computational requirements, usually set in the scientific domain, to utilize a technically…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-15 Gary A. McGilvary , Adam Barker , Ashley Lloyd , Malcolm Atkinson

Petabytes of data are to be processed and stored requiring millions of CPU-years in high energy particle (HEP) physics event simulation. This enormous demand is handled in worldwide distributed computing centers as part of the LHC computing…

Instrumentation and Detectors · Physics 2017-04-26 T. Harenberg , N. Lang , P. Mättig , M. Sandhoff , F. Volkmer , T. Kuhl , C. Schwanenberger

This paper reports on the state of the art of virtualization technology for both general purpose domains as well as real-time domains. There exits no entirely instantaneous data transmission/transfer. There always exist a delay while…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-03-27 Carlos Antonio Perea-Gómez

Within the field of biocybersecurity, it is important to understand what vulnerabilities may be uncovered in the processing of biologics as well as how they can be safeguarded as they intersect with cyber and cyberphysical systems, as noted…

Cryptography and Security · Computer Science 2020-05-06 Lucas Potter , Xavier-Lewis Palmer

The U.S. Virtual Astronomical Observatory (VAO) is a product-driven organization that provides new scientific research capabilities to the astronomical community. Software development for the VAO follows a lightweight framework that guides…

Incidents in microservice environments can be costly and challenging to recover from due to their complexity and distributed nature. Recent advancements in artificial intelligence (AI) offer promising solutions for improving incident…

Software Engineering · Computer Science 2024-10-08 Dahlia Ziqi Zhou , Marios Fokaefs

Our society has been increasingly witnessing a number of negative, unintended consequences of digital technologies. While post-hoc policy regulation is crucial in addressing these issues, reasonably anticipating the consequences before…

Human-Computer Interaction · Computer Science 2023-04-13 Rock Yuren Pang , Katharina Reinecke

Business success of companies heavily depends on the availability and performance of their client applications. Due to modern development paradigms such as DevOps and microservice architectural styles, applications are decoupled into…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-02-10 Sina Niedermaier , Falko Koetter , Andreas Freymann , Stefan Wagner

As AI-based clinical decision support (AI-CDS) is introduced in more and more aspects of healthcare services, HCI research plays an increasingly important role in designing for complementarity between AI and clinicians. However, current…

Human-Computer Interaction · Computer Science 2025-04-11 Venkatesh Sivaraman , Katelyn Morrison , Will Epperson , Adam Perer

Hybrid systems with both discrete and continuous dynamics are an important model for real-world cyber-physical systems. The key challenge is to ensure their correct functioning w.r.t. safety requirements. Promising techniques to ensure…

Logic in Computer Science · Computer Science 2015-05-27 Stefan Mitsch , Grant Olney Passmore , Andre Platzer

The vast majority of the long tail of scientific software, the myriads of tools that implement the many analysis and visualization methods for different scientific fields, is highly specialized, purpose-built for a research project, and has…

Software Engineering · Computer Science 2013-09-10 Daisie Huang , Hilmar Lapp

As software continues to permeate nearly every facet of modern life, the complexity and ubiquity of digital services underscore the need for sustainable, effective, and inclusive software development practices. Although software engineering…

Software Engineering · Computer Science 2025-07-01 Benoit Combemale