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Common models of circadian rhythms are constructed as compartmental reactions of well mixed biochemicals involving a negative-feedback loop containing several intermediate reaction steps in order to enable oscillations. Spatial transport of…

Biological Physics · Physics 2023-03-22 Pablo Rojas , Oreste Piro , Martin E. Garcia

A model of coupled molecular oscillators is proposed to study nonequilibrium thermodynamics of synchronization. We find that synchronization of nonequilibrium oscillators costs energy even when the oscillator-oscillator coupling is…

Biological Physics · Physics 2020-01-29 Dongliang Zhang , Yuansheng Cao , Qi Ouyang , Yuhai Tu

A wide range of organisms features molecular machines, circadian clocks, which generate endogenous oscillations with ~24 h periodicity and thereby synchronize biological processes to diurnal environmental fluctuations. Recently, it has…

Molecular Networks · Quantitative Biology 2016-02-03 Mathias Foo , David E. Somers , Pan-Jun Kim

A driven linear oscillator and a feedback mechanism are two necessary elements of any classical periodic clock. Here, we introduce a novel, fully quantum clock using a driven oscillator in the quantum regime and coherent quantum feedback.…

Quantum Physics · Physics 2024-10-31 Stefan Zeppetzauer , Leonardo Assis Morais , Xin He , Gerard Milburn , Arkady Fedorov

Circadian clocks must be able to entrain to time-varying signals to keep their oscillations in phase with the day-night rhythm. On the other hand, they must also exhibit input compensation: their period must remain about one day in…

Biological Physics · Physics 2017-07-13 Joris Paijmans , David K Lubensky , Pieter Rein ten Wolde

We describe quantum behaviors of a simple harmonic oscillator, starting from the classical mechanics. By imposing two conditions on the phase points generated from a symplectic algorithm, we obtain discrete energy levels, satisfying $E_n…

Quantum Physics · Physics 2013-07-02 Sangrak Kim

For the first time in history, humankind might conceivably begin to imagine itself as a multi-planetary species. This goal will entail technical innovation in a number of contexts, including that of healthcare. All life on Earth shares an…

Biological Physics · Physics 2024-11-07 Betony Adams , Abbas Hassasfar , Ilya Sinayskiy , Alistair Nunn , Geoffrey Guy , Francesco Petruccione

The circadian clock can adapt itself to external cues, but the molecular mechanisms and regulatory networks governing circadian oscillations' transient adjustments are still largely unknown. Here we consider the specific case of circadian…

Molecular Networks · Quantitative Biology 2023-04-18 Ziyu Zhao , Dae-Sung Hwangbo , Sumit Saurabh , Clark Rosensweig , Ravi Allada , William L. Kath , Rosemary Braun

Periodic quantum oscillations of a rectified dc voltage Vdc(B) vs the perpendicular magnetic field B were measured near the critical temperature Tc in a single superconducting aluminum almost symmetric ring (without specially created…

Superconductivity · Physics 2007-11-28 V. I. Kuznetsov , A. A. Firsov , S. V. Dubonos

We introduce a computational framework for simulating non-adiabatic vibronic dynamics on circuit quantum electrodynamics (cQED) platforms. Our approach leverages hybrid oscillator-qubit quantum hardware with mid-circuit measurements and…

Quantum Physics · Physics 2025-10-27 Nam P. Vu , Daniel Dong , Xiaohan Dan , Ningyi Lyu , Victor Batista , Yuan Liu

Many intracellular processes continue to oscillate during the cell cycle. Although it is not well-understood how they are affected by discontinuities in the cellular environment, the general assumption is that oscillations remain robust…

Molecular Networks · Quantitative Biology 2014-09-25 David S. Tourigny

We demonstrate that the coupling of excitonic and vibrational motion in biological complexes can provide mechanisms to explain the long-lived oscillations that have been obtained in non linear spectroscopic signals of different…

Chemical Physics · Physics 2015-06-17 M. B. Plenio , J. Almeida , S. F. Huelga

We study the impact of light on the mammalian circadian system using the theory of phase response curves. Using a recently developed ansatz we derive a low-dimensional macroscopic model for the core circadian clock in mammals.…

Neurons and Cognition · Quantitative Biology 2019-10-14 Kevin M. Hannay , Daniel B. Forger , Victoria Booth

Oscillatory chemical reactions often serve as a timing clock of cellular processes in living cells. The temporal dynamics of protein concentration levels is thus of great interest in biology. Here we propose a theoretical framework to…

Systems and Control · Computer Science 2015-03-20 Yutaka Hori , Shinji Hara

A number of biological rhythms originate from networks comprised of multiple cellular oscillators. But analytical results are still lacking on the collective oscillation period of inter-coupled gene regulatory oscillators, which, as has…

Systems and Control · Computer Science 2014-02-26 Yongqiang Wang , Yutaka Hori , Shinji Hara , Francis J. Doyle

We explore the quantum version of Brayton cycle with a composite system as the working substance. The actual Brayton cycle consists of two adiabatic and two isobaric processes. Two pressures can be defined in our isobaric process, one…

Quantum Physics · Physics 2013-02-04 X. L. Huang , L. C. Wang , X. X. Yi

The green microscopic alga Ostreococcus tauri has recently emerged as a promising model for understanding how circadian clocks, which drive the daily biological rythms of many organisms, synchronize to the day/night cycle in changing…

Quantitative Methods · Quantitative Biology 2012-01-04 Quentin Thommen , Benjamin Pfeuty , Florence Corellou , François-Yves Bouget , Marc Lefranc

A classical linear oscillator is treated in the small amplitude limit so that it will be approximately relativistic. The oscillator involves a charge particle in a linear potential in classical zero-point radiation. It is found that the…

Classical Physics · Physics 2026-03-17 Timothy H. Boyer

Cyclic motions in vertebrates, including heart beating, breathing and walking, are derived by a network of biological oscillators having fascinating features such as entrainment, environment adaptation, and robustness. These features…

Adaptation and Self-Organizing Systems · Physics 2021-11-24 Venus Pasandi , Aiko Dinale , Mehdi Keshmiri , Daniele Pucci

Nearly all circadian clocks maintain a period that is insensitive to temperature changes, a phenomenon known as temperature compensation (TC). Yet, it is unclear whether there is any common feature among different systems that exhibit TC.…

Molecular Networks · Quantitative Biology 2024-01-26 Haochen Fu , Chenyi Fei , Qi Ouyang , Yuhai Tu