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The manner in which groups of neurons represent events in the external world is fundamental to neuroscience. Here, we analyze the population code of the retina during naturalistic stimulation and show that the information conveyed by…

Neurons and Cognition · Quantitative Biology 2007-05-23 Elad Schneidman , Jason L. Puchalla , Ronen Segev , Robert A. Harris , William Bialek , Michael J. Berry

Why do neurons communicate through spikes? By definition, spikes are all-or-none neural events which occur at continuous times. In other words, spikes are on one side binary, existing or not without further details, and on the other can…

Neurons and Cognition · Quantitative Biology 2024-04-12 Antoine Grimaldi , Amélie Gruel , Camille Besnainou , Jean-Nicolas Jérémie , Jean Martinet , Laurent U Perrinet

Sensory perception originates from the responses of sensory neurons, which react to a collection of sensory signals linked to various physical attributes of a singular perceptual object. Unraveling how the brain extracts perceptual…

Neurons and Cognition · Quantitative Biology 2025-10-27 Zhichao Zhu , Yang Qi , Wenlian Lu , Jianfeng Feng

The correlated variability in the responses of a neural population to the repeated presentation of a sensory stimulus is a universally observed phenomenon. Such correlations have been studied in much detail, both with respect to their…

Neurons and Cognition · Quantitative Biology 2018-07-04 Volker Pernice , Rava Azeredo da Silveira

Brain encoding and decoding aims to understand the relationship between external stimuli and brain activities, and is a fundamental problem in neuroscience. In this article, we study latent embedding alignment for brain encoding and…

Methodology · Statistics 2026-03-24 Shuoxun Xu , Zhanhao Yan , Lexin Li

Information processing in the brain crucially depends on encoding properties of single neurons, with particular relevance of the spike-generation mechanism. The latter hinges upon the bifurcation type at the transition point between resting…

Neurons and Cognition · Quantitative Biology 2017-05-10 Janina Hesse , Jan-Hendrik Schleimer , Susanne Schreiber

The synergy between spiking neural networks and neuromorphic hardware holds promise for the development of energy-efficient AI applications. Inspired by this potential, we revisit the foundational aspects to study the capabilities of…

Neural and Evolutionary Computing · Computer Science 2024-03-18 Manjot Singh , Adalbert Fono , Gitta Kutyniok

Decoding brain signals accurately and efficiently is crucial for intra-cortical brain-computer interfaces. Traditional decoding approaches based on neural activity vector features suffer from low accuracy, whereas deep learning based…

Human-Computer Interaction · Computer Science 2025-04-15 Song Yang , Haotian Fu , Herui Zhang , Peng Zhang , Wei Li , Dongrui Wu

Over repeat presentations of the same stimulus, sensory neurons show variable responses. This "noise" is typically correlated between pairs of cells, and a question with rich history in neuroscience is how these noise correlations impact…

Neurons and Cognition · Quantitative Biology 2015-06-16 Yu Hu , Joel Zylberberg , Eric Shea-Brown

A main concern in cognitive neuroscience is to decode the overt neural spike train observations and infer latent representations under neural circuits. However, traditional methods entail strong prior on network structure and hardly meet…

Neurons and Cognition · Quantitative Biology 2019-11-22 Zhijie Chen , Junchi Yan , Longyuan Li , Xiaokang Yang

Neural decoding, the process of understanding how brain activity corresponds to different stimuli, has been a primary objective in cognitive sciences. Over the past three decades, advances in functional Magnetic Resonance Imaging (fMRI) and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Yanchen Wang , Adam Turnbull , Tiange Xiang , Yunlong Xu , Sa Zhou , Adnan Masoud , Shekoofeh Azizi , Feng Vankee Lin , Ehsan Adeli

At the level of individual neurons, various coding properties can be inferred from the input-output relationship of a cell. For small inputs, this relation is captured by the phase-response curve (PRC), which measures the effect of a small…

Neurons and Cognition · Quantitative Biology 2026-01-14 Janina Hesse , Susanne Schreiber

Experimental studies support the notion of spike-based neuronal information processing in the brain, with neural circuits exhibiting a wide range of temporally-based coding strategies to rapidly and efficiently represent sensory stimuli.…

Neural and Evolutionary Computing · Computer Science 2020-08-18 Brian Gardner , André Grüning

Most neurons in the primary visual cortex initially respond vigorously when a preferred stimulus is presented, but adapt as stimulation continues. The functional consequences of adaptation are unclear. Typically a reduction of firing rate…

Neurons and Cognition · Quantitative Biology 2011-03-15 J. M. Cortes , D. Marinazzo , P. Series , M. W. Oram , T. J. Sejnowski , M. C. W. van Rossum

In this paper we introduce Neural Network Coding(NNC), a data-driven approach to joint source and network coding. In NNC, the encoders at each source and intermediate node, as well as the decoder at each destination node, are neural…

Information Theory · Computer Science 2021-01-12 Litian Liu , Amit Solomon , Salman Salamatian , Muriel Medard

Decoding behavior, perception, or cognitive state directly from neural signals has applications in brain-computer interface research as well as implications for systems neuroscience. In the last decade, deep learning has become the…

Neurons and Cognition · Quantitative Biology 2020-05-21 Jesse A. Livezey , Joshua I. Glaser

The timing of individual neuronal spikes is essential for biological brains to make fast responses to sensory stimuli. However, conventional artificial neural networks lack the intrinsic temporal coding ability present in biological…

Neural and Evolutionary Computing · Computer Science 2020-11-18 Iulia M. Comsa , Krzysztof Potempa , Luca Versari , Thomas Fischbacher , Andrea Gesmundo , Jyrki Alakuijala

One step in the conventional analysis of extracellularly recorded neuronal data is spike sorting, which separates electrical signal into action potentials from different neurons. Because spike sorting involves human judgment, it can be…

Neurons and Cognition · Quantitative Biology 2007-05-23 Artur Luczak , Nandakumar S. Narayanan

The success of deep learning in the past decade is partially shrouded in the shadow of adversarial attacks. In contrast, the brain is far more robust at complex cognitive tasks. Utilizing the advantage that neurons in the brain communicate…

Neurons and Cognition · Quantitative Biology 2023-06-12 Jianhao Ding , Zhaofei Yu , Tiejun Huang , Jian K. Liu

To evaluate the nature of the neural code in the cerebral cortex, we have used a combination of theory and experiment to assess how information is represented in a realistic cortical population response. We have shown how a sensory stimulus…

Neurons and Cognition · Quantitative Biology 2008-03-28 L. C. Osborne , S. E. Palmer , S. G. Lisberger , W. Bialek