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Approaches to predicting neuronal spike responses commonly use a Poisson learning objective. This objective quantizes responses into spike counts within a fixed summation interval, typically on the order of 10 to 100 milliseconds in…

Neurons and Cognition · Quantitative Biology 2024-07-03 Kevin Doran , Marvin Seifert , Carola A. M. Yovanovich , Tom Baden

Cortical neurons are characterized by irregular firing and a broad distribution of rates. The balanced state model explains these observations with a cancellation of mean excitatory and inhibitory currents, which makes fluctuations drive…

Neurons and Cognition · Quantitative Biology 2020-10-15 Alessandro Sanzeni , Mark H Histed , Nicolas Brunel

We investigate a network model in which a single random walker combines local diffusion with preferential resetting to previously visited nodes. Each arrival deposits one unit of stress on the target node, and threshold crossings trigger…

Statistical Mechanics · Physics 2026-04-14 Mohammad Jafari

A central question in computational neuroscience is how structure determines function in neural networks. The emerging high-quality large-scale connectomic datasets raise the question of what general functional principles can be gleaned…

Neurons and Cognition · Quantitative Biology 2022-10-25 Weishun Zhong , Ben Sorscher , Daniel D Lee , Haim Sompolinsky

The instantaneous state of a neural network consists of both the degree of excitation of each neuron, the network is composed of, and positions of impulses in communication lines between neurons. In neurophysiological experiments, the…

Neurons and Cognition · Quantitative Biology 2015-03-17 Kseniya Kravchuk , Alexander Vidybida

Understanding the relationship between brain activity and behavior is a central goal of neuroscience. Despite significant advances, a fundamental dichotomy persists: neural activity manifests as both discrete spikes of individual neurons…

Neurons and Cognition · Quantitative Biology 2025-11-11 Kasra Jalaldoust , Erfan Zabeh

We study pattern formation in class of a large-dimensional neural networks posed on random graphs and subject to spatio-temporal stochastic forcing. Under generic conditions on coupling and nodal dynamics, we prove that the network admits a…

Probability · Mathematics 2025-08-26 Daniele Avitabile , James MacLaurin

Neural population activity often exhibits rich variability and temporal structure. This variability is thought to arise from single-neuron stochasticity, neural dynamics on short time-scales, as well as from modulations of neural firing…

Machine Learning · Statistics 2014-10-14 Mijung Park , Jakob H. Macke

One of the major challenges in neuroscience is to determine how noise that is present at the molecular and cellular levels affects dynamics and information processing at the macroscopic level of synaptically coupled neuronal populations.…

Disordered Systems and Neural Networks · Physics 2014-06-12 Paul C. Bressloff , Jay M. Newby

Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow

The relationship between complex, brain oscillations and the dynamics of individual neurons is poorly understood. Here we utilize Maximum Caliber, a dynamical inference principle, to build a minimal, yet general model of the collective…

Neurons and Cognition · Quantitative Biology 2020-09-04 Corey Weistuch , Lilianne R. Mujica-Parodi , Ken Dill

The activity of a neural network is defined by patterns of spiking and silence from the individual neurons. Because spikes are (relatively) sparse, patterns of activity with increasing numbers of spikes are less probable, but with more…

Neurons and Cognition · Quantitative Biology 2025-02-13 Gasper Tkacik , Thierry Mora , Olivier Marre , Dario Amodei , Michael J. Berry , William Bialek

We study a simple model for a neuron function in a collective brain system. The neural network is composed of uncorrelated random scale-free network for eliminating the degree correlation of dynamical processes. The interaction of neurons…

Statistical Mechanics · Physics 2007-05-23 Kyoung Eun Lee , Jae Woo Lee

We establish a large deviation principle for the trajectories of Wiener processes subject to random resets to the origin occurring according to a Poisson process. In addition to the pathwise large deviation principle, we identify the rate…

Probability · Mathematics 2025-12-09 A. V. Logachov , O. M. Logachova , A. A. Yambartsev , K. A. Zaykov

The plasticity of the conduction delay between neurons plays a fundamental role in learning. However, the exact underlying mechanisms in the brain for this modulation is still an open problem. Understanding the precise adjustment of…

Neural and Evolutionary Computing · Computer Science 2020-11-19 Alireza Nadafian , Mohammad Ganjtabesh

Information measures are often used to assess the efficacy of neural networks, and learning rules can be derived through optimization procedures on such measures. In biological neural networks, computation is restricted by the amount of…

Neurons and Cognition · Quantitative Biology 2021-03-12 Dmytro Grytskyy , Renaud B. Jolivet

Whether an idea, information, infection, or innovation diffuses throughout a society depends not only on the structure of the network of interactions, but also on the timing of those interactions. Recent studies have shown that diffusion…

Physics and Society · Physics 2017-12-19 Mohammad Akbarpour , Matthew O. Jackson

Understanding how recurrent neural circuits can learn to implement dynamical systems is a fundamental challenge in neuroscience. The credit assignment problem, i.e. determining the local contribution of each synapse to the network's global…

Neurons and Cognition · Quantitative Biology 2017-08-08 Alireza Alemi , Christian Machens , Sophie Denève , Jean-Jacques Slotine

Population equations for infinitely large networks of spiking neurons have a long tradition in theoretical neuroscience. In this work, we analyze a recent generalization of these equations to populations of finite size, which takes the form…

Probability · Mathematics 2022-08-30 Valentin Schmutz , Eva Löcherbach , Tilo Schwalger

We study the spike statistics of neurons in a network with dynamically balanced excitation and inhibition. Our model, intended to represent a generic cortical column, comprises randomly connected excitatory and inhibitory leaky…

Neurons and Cognition · Quantitative Biology 2007-05-23 Alexander Lerchner , Cristina Ursta , John Hertz , Mandana Ahmadi , Pauline Ruffiot