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We propose a physical model for developmental process at cellular level to discuss the mechanism of epigenetic landscape. In our simplified model, a minimal model, the network of the interaction among cells generates the landscape…

Cell Behavior · Quantitative Biology 2014-02-04 Motoki Nakagawa , Osamu Narikiyo

The rapid development of urbanization during the past decades has significantly improved people's lives but also introduced new challenges on effective functional urban planning and transportation management. The functional regions defined…

Artificial Intelligence · Computer Science 2019-08-02 Zhuochen Jin , Nan Cao , Yang Shi , Hanghang Tong , Yingcai Wu

As cities struggle to adapt to more ``people-centered'' urbanism, transportation planning and engineering must innovate to expand the street network strategically in order to ensure efficiency but also to deter sprawl. Here, we conducted a…

Physics and Society · Physics 2021-11-16 Gabriel L. Maia , Caio Ponte , Carlos Caminha , Lara Furtado , Hygor P. M. Melo , Vasco Furtado

Most large cities are spanned by more than one transportation system. These different modes of transport have usually been studied separately: it is however important to understand the impact on urban systems of the coupling between them…

Physics and Society · Physics 2015-09-30 Emanuele Strano , Saray Shai , Simon Dobson , Marc Barthelemy

Many societies are organized in networks that are formed by people who meet and interact over time. In this paper, we present a first model to capture the micro-foundations of social networks evolution, where boundedly rational agents of…

Social and Information Networks · Computer Science 2015-08-17 Ahmed M. Alaa , Kartik Ahuja , Mihaela van der Schaar

The dynamics of urban systems can be understood from an evolutionary perspective, in some sense extending biological and cultural evolution. Models for systems of cities implementing elementary evolutionary processes remain however to be…

Physics and Society · Physics 2020-05-01 Juste Raimbault

Barriers in cities, such as administrative boundaries, natural obstacles, railways or major roads are thought to induce segregation. However, the empirical knowledge about this phenomenon is limited. Here, we present a network science…

Physics and Society · Physics 2025-08-13 Gergő Pintér , Balázs Lengyel

Urban economic vitality is a crucial indicator of a city's long-term growth potential, comprising key metrics such as the annual number of new companies and the population employed. However, modeling urban economic vitality remains…

Artificial Intelligence · Computer Science 2025-12-01 Xiaofeng Li , Xiangyi Xiao , Xiaocong Du , Ying Zhang , Haipeng Zhang

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

Molecular Networks · Quantitative Biology 2024-02-16 Claus Kadelka , David Murrugarra

This morphological study identifies and measures recent nationwide trends in American street network design. Historically, orthogonal street grids provided the interconnectivity and density that researchers identify as important factors for…

Physics and Society · Physics 2020-10-13 Geoff Boeing

Development combines three basic processes asymmetric --- cell division, signaling and gene regulation --- in a multitude of ways to create an overwhelming diversity of multicellular life-forms. Here, we attempt to chart this diversity…

Molecular Networks · Quantitative Biology 2020-01-01 Somya Mani , Tsvi Tlusty

Due to the complexity of the traffic flow dynamics in urban road networks, most quantitative descriptions of city traffic so far are based on computer simulations. This contribution pursues a macroscopic (fluid-dynamic) simulation approach,…

Fluid Dynamics · Physics 2015-03-18 Amin Mazloumian , Nikolas Geroliminis , Dirk Helbing

From our experiences in the past, we have seen that the growth of cities is very much dependent on the transportation networks. In mega cities, transportation networks determine to a significant extent as to where the people will move and…

Artificial Intelligence · Computer Science 2018-02-08 Saptarshi Pal , Soumya K Ghosh

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random…

Biological Physics · Physics 2009-11-07 L. C. Hsieh , L. F. Luo , F. M. Ji , H. C. Lee

Capturing the structure of a population and characterising contacts within the population are key to reliable projections of infectious disease. Two main elements of population structure -- contact heterogeneity and age -- have been…

Physics and Society · Physics 2025-03-17 Luke Murray Kearney , Emma L. Davis , Matt J. Keeling

We propose a minimal off-lattice model of living organisms where just a very few dynamical rules of growth are assumed. The stable coexistence of many clusters is detected when we replace the global restriction rule by a locally applied…

Physics and Society · Physics 2021-08-19 B. F. de Oliveira , M. V. de Moraes , D. Bazeia , A. Szolnoki

In this paper we revisit the concept of mobility entropy. Over time, the structure of spatial interactions among urban centres tends to become more complex and evolves from centralised models to more scattered origin and destination…

Physics and Society · Physics 2021-06-30 Valentina Marin , Carlos Molinero , Elsa Arcaute

We present here a study of the clustering and cycles present in the graph of Internet at the Autonomous Systems level. Even if the whole structure is changing with time, we present some evidence that the statistical distributions of cycles…

Disordered Systems and Neural Networks · Physics 2007-05-23 Ginestra Bianconi , Guido Caldarelli , Andrea Capocci

How do real graphs evolve over time? What are ``normal'' growth patterns in social, technological, and information networks? Many studies have discovered patterns in static graphs, identifying properties in a single snapshot of a large…

Physics and Society · Physics 2007-05-23 Jure Leskovec , Jon Kleinberg , Christos Faloutsos