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Related papers: Flexible and robust networks

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We consider networks with two types of nodes. The v-nodes, called centers, are hyperconnected and interact one to another via many u-nodes, called satellites. This centralized architecture, widespread in gene networks, realize a bow-tie…

Molecular Networks · Quantitative Biology 2012-03-02 Sergei Vakulenko , Ovidiu Radulescu

We consider continuous time Hopfield-like recurrent networks as dynamical models for gene regulation and neural networks. We are interested in networks that contain n high-degree nodes preferably connected to a large number of Ns weakly…

Molecular Networks · Quantitative Biology 2016-08-03 Sergei Vakulenko , Ivan Morozov , Ovidiu Radulescu

Many biological, technological, and social systems can be effectively described as networks of interacting subsystems. Typically, these networks are not isolated objects, but interact with their environment through both signals and…

Systems and Control · Electrical Eng. & Systems 2026-01-06 Amirhossein Nazerian , Malbor Asllani , Melvyn Tyloo , Wai Lim Ku , Francesco Sorrentino

Robustness to mutations and noise has been shown to evolve through stabilizing selection for optimal phenotypes in model gene regulatory networks. The ability to evolve robust mutants is known to depend on the network architecture. How do…

Molecular Networks · Quantitative Biology 2008-07-07 Volkan Sevim , Per Arne Rikvold

Systems as diverse as genetic networks or the world wide web are best described as networks with complex topology. A common property of many large networks is that the vertex connectivities follow a scale-free power-law distribution. This…

Disordered Systems and Neural Networks · Physics 2015-06-25 Albert-Laszlo Barabasi , Reka Albert

We model the robustness against random failure or intentional attack of networks with arbitrary large-scale structure. We construct a block-based model which incorporates --- in a general fashion --- both connectivity and interdependence…

Physics and Society · Physics 2012-09-25 Tiago P. Peixoto , Stefan Bornholdt

Complex networks have recently attracted much interest due to their prevalence in nature and our daily lives [1, 2]. A critical property of a network is its resilience to random breakdown and failure [3-6], typically studied as a…

Physics and Society · Physics 2016-01-08 James P. Bagrow , Sune Lehmann , Yong-Yeol Ahn

Genetic regulatory networks are defined by their topology and by a multitude of continuously adjustable parameters. Here we present a class of simple models within which the relative importance of topology vs. interaction strengths becomes…

Molecular Networks · Quantitative Biology 2013-08-02 Mikhail Tikhonov , William Bialek

One of the characteristic features of genetic networks is their inherent robustness, that is, their ability to retain functionality in spite of the introduction of random errors. In this paper, we seek to better understand how robustness is…

Molecular Networks · Quantitative Biology 2009-04-29 Arnab Bhattacharyya , Bernhard Haeupler

Dynamics in biological networks are in general robust against several perturbations. We investigate a coupled map network as a model motivated by gene regulatory networks and design systems which are robust against phenotypic perturbations…

Molecular Networks · Quantitative Biology 2015-03-20 Nen Saito , Macoto Kikuchi

Oscillation has an important role in bio-dynamical systems such as circadian rhythms and eukaryotic cell cycle. John Tyson et. al. in Nature Review Mol Cell Biol 2008 examined a limited number of network topologies consisting of three nodes…

Molecular Networks · Quantitative Biology 2011-10-14 Matthew Bailey , Jaewook Joo

Stars and cycles are basic structures in network construction. The former has been well studied in network analysis, while the latter attracted rare attention. A node together with its neighbors constitute a neighborhood star-structure…

Physics and Society · Physics 2019-03-13 Tianlong Fan , Linyuan Lü , Dinghua Shi

We study the oscillatory behaviour of a gene regulatory network with interlinked positive and negative feedback loop. Frequency and amplitude are two important properties of oscillation. Studied network produces two different modes of…

Molecular Networks · Quantitative Biology 2015-12-21 Rajesh Karmakar

Complex networks are ubiquitous: a cell, the human brain, a group of people and the Internet are all examples of interconnected many-body systems characterized by macroscopic properties that cannot be trivially deduced from those of their…

The concept of robustness of regulatory networks has been closely related to the nature of the interactions among genes, and the capability of pattern maintenance or reproducibility. Defining this robustness property is a challenging task,…

Molecular Networks · Quantitative Biology 2007-10-24 Madalena Chave , Eduardo D. Sontag , Anirvan M. Sengupta

The relationship between network topology and system dynamics has significant implications for unifying our understanding of the interplay among metabolic, gene-regulatory, and ecosystem network architecures. Here we analyze the stability…

Populations and Evolution · Quantitative Biology 2015-06-17 Cameron Smith , Raymond S. Puzio , Aviv Bergman

Many complex systems can be described in terms of networks of interacting units. Recent studies have shown that a wide class of both natural and artificial nets display a surprisingly widespread feature: the presence of highly heterogeneous…

Disordered Systems and Neural Networks · Physics 2007-05-23 R. Ferrer i Cancho , R. V. Sole

The rapid advancement of technology underscores the critical importance of robustness in complex network systems. This paper presents a framework for investigating the structural robustness of interconnected network models. This paper…

Physics and Society · Physics 2023-11-01 Dong Gaogao , Sun Nannan , Wang Fan

Generative mechanisms which lead to empirically observed structure of networked systems from diverse fields like biology, technology and social sciences form a very important part of study of complex networks. The structure of many…

Physics and Society · Physics 2015-12-03 Snehal M. Shekatkar , G. Ambika

A common definition of a robust connection between two nodes in a network such as a communication network is that there should be at least two independent paths connecting them, so that the failure of no single node in the network causes…

Statistical Mechanics · Physics 2008-04-07 M. E. J. Newman , Gourab Ghoshal
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