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Sperm motility is a prerequisite for male fertility. Enhancing the concentration of motile sperms in assisted reproductive technologies - for human and animal reproduction - is typically achieved through aggressive methods such as…

Several micro-organisms, such as bacteria, algae, or spermatozoa, use flagella or cilia to swim in a fluid, while many other micro-organisms instead use ample shape deformation, described as amoeboid, to propel themselves by either crawling…

Biological Physics · Physics 2016-09-19 Hao Wu , A. Farutin , W. -F. Hu , M. Thiébaud , S. Rafaï , P. Peyla , M. -C. Lai , C. Misbah

The propulsion of mammalian spermatozoa relies on the spontaneous periodic oscillation of their flagella. These oscillations are driven internally by the coordinated action of ATP-powered dynein motors that exert sliding forces between…

Fluid Dynamics · Physics 2022-10-13 Chenji Li , Brato Chakrabarti , Pedro Castilla , Achal Mahajan , David Saintillan

There is increasing evidence that mammalian cells not only crawl on substrates but can also swim in fluids. To elucidate the mechanisms of the onset of motility of cells in suspension, a model which couples actin and myosin kinetics to…

Biological Physics · Physics 2019-09-18 Alexander Farutin , Jocelyn Etienne , Chaouqi Misbah , Pierre Recho

Bacteria commonly live in structured communities that affect human health and influence ecological systems. Heterogeneous populations, such as motile and non-motile populations, often coexist in bacteria communities. Motile subpopulations…

Biological Physics · Physics 2019-06-19 Haoran Xu , Justas Dauparas , Debasish Das , Eric Lauga , Yilin Wu

Eukaryotic swimming cells such as spermatozoa, algae or protozoa use flagella or cilia to move in viscous fluids. The motion of their flexible appendages in the surrounding fluid induces propulsive forces that balance with the viscous drag…

Soft Condensed Matter · Physics 2023-10-06 Maciej Lisicki , Marcos F. Velho Rodrigues , Eric Lauga

Sperm cooperation has evolved in a variety of taxa and is often considered a response to sperm competition, yet the benefit of this form of collective movement remains unclear. Here we use fine-scale imaging and a minimal mathematical model…

Cell Behavior · Quantitative Biology 2014-07-03 H. S. Fisher , L. Giomi , H. E. Hoekstra , L. Mahadevan

Eukaryotic cell motility is crucial during development, wound healing, the immune response, and cancer metastasis. Some eukaryotic cells can swim, but cells more commonly adhere to and crawl along the extracellular matrix. We study the…

Cell Behavior · Quantitative Biology 2019-09-02 Melissa H. Mai , Brian A. Camley

The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates. Recent experiments,…

Cell Behavior · Quantitative Biology 2024-12-24 Pedrom Zadeh , Brian A. Camley

The enteric bacterium Proteus mirabilis, which is a pathogen that forms biofilms in vivo, can swarm over hard surfaces and form concentric ring patterns in colonies. Colony formation involves two distinct cell types: swarmer cells that…

Populations and Evolution · Quantitative Biology 2015-05-28 Chuan Xue , Elena O. Budrene , Hans G. Othmer

Many microorganisms live and evolve in complex fluids. Examples include mammalian spermatozoa in cervical mucus, worms (e.g., \textit{C. elegans}) in wet soil, and bacteria (e.g., \textit{H. pylori}) in our stomach lining. Due to the…

Fluid Dynamics · Physics 2022-10-21 Paulo E. Arratia

Spermatozoa self-propel by propagating bending waves along a predominantly active elastic flagellum. The organized structure of the "9 + 2" axoneme is lost in the most-distal few microns of the flagellum, and therefore this region is…

Sperm cells perform extremely demanding tasks with minimal capabilities. The cells must quickly navigate in a noisy environment to find an egg within a short time window for successful fertilization without any global positioning…

Optimization and Control · Mathematics 2022-12-21 Mahmoud Abdelgalil , Yasser Aboelkassem , Haithem Taha

Microscopic swimmers, e.g., chemotactic bacteria and cells, are capable of directed motion by exerting a force on their environment. For asymmetric microswimmers, e.g., bacteria, spermatozoa and many artificial active colloidal particles, a…

Soft Condensed Matter · Physics 2013-07-09 Mite Mijalkov , Giovanni Volpe

Unicellular microscopic organisms living in aqueous environments outnumber all other creatures on Earth. A large proportion of them are able to self-propel in fluids with a vast diversity of swimming gaits and motility patterns. In this…

Biological Physics · Physics 2021-07-14 Marcos F. Velho Rodrigues , Maciej Lisicki , Eric Lauga

Swimming micro-organisms such as bacteria or spermatozoa are typically found in dense suspensions, and exhibit collective modes of locomotion qualitatively different from that displayed by isolated cells. In the dilute limit where…

Biological Physics · Physics 2010-05-02 Sebastien Michelin , Eric Lauga

Locomotion is essential for living cells. It enables bacteria and algae to explore space for food, cancer to spread, and immune system to fight infections. Motile cells display trajectories of intriguing complexity, from regular (e.g.…

Soft Condensed Matter · Physics 2021-12-28 C. Misbah , M. S. Rizvi , W. F. Hu , T. S. Lin , S. Rafai , A. Farutin

The hydrodynamic flow field generated by self-propelled active particles and swimming microorganisms is strongly altered by the presence of nearby boundaries in a viscous flow. Using a simple model three-linked sphere swimmer, we show that…

Fluid Dynamics · Physics 2018-04-18 Abdallah Daddi-Moussa-Ider , Maciej Lisicki , Christian Hoell , Hartmut Löwen

Biological microswimmers often encounter deformable boundaries in physiological conditions; for instance, the viscoelastic walls of reproductive tract during migration of spermatozoa, or host tissue during early bacterial biofilm formation.…

Soft Condensed Matter · Physics 2025-08-07 Smita S. Sontakke , Aneesha Kajampady , Mohd Suhail Rizvi , Ranabir Dey

We perform a detailed analysis of the migratory motion of human embryonic stem cells in two-dimensions, both when isolated and in close proximity to another cell, recorded with time-lapse microscopic imaging. We show that isolated cells…

Cell Behavior · Quantitative Biology 2018-03-02 L E Wadkin , S Orozco-Fuentes , I Neganova , G Swan , A Laude , M Lako , A Shukurov , N G Parker