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We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

Quantitative Methods · Quantitative Biology 2014-05-16 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

Regression analysis is commonly conducted in survey sampling. However, existing methods fail when the relationships vary across different areas or domains. In this paper, we propose a unified framework to study the group-wise covariate…

Methodology · Statistics 2024-09-25 Mingjun Gang , Xin Wang , Zhonglei Wang , Wei Zhong

In many phase II trials in solid tumours, patients are assessed using endpoints based on the Response Evaluation Criteria in Solid Tumours (RECIST) scale. Often, analyses are based on the response rate. This is the proportion of patients…

Methodology · Statistics 2017-03-02 Chien-Ju Lin , James Wason

Learning about causal effects in target populations and their subsets may be facilitated by combining information from multiple sources. One major class of study designs that combine information involves appending an index study with data…

The objectives of this paper are to explore ways to analyze breast cancer dataset in the context of unsupervised learning without prior training model. The paper investigates different ways of clustering techniques as well as preprocessing.…

Machine Learning · Computer Science 2021-09-06 Somenath Chakraborty , Beddhu Murali

Self-selected samples are frequently obtained due to different levels of survey participation propensity of the survey individuals. When the survey participation is related to the survey topic of interest, propensity score weighting…

Applications · Statistics 2014-11-24 Sixia Chen , Jae-Kwang Kim

Often a screening or selection experiment targets a cell or tissue, which presents many possible molecular targets and identifies a correspondingly large number of ligands. We describe a statistical method to extract an estimate of the…

Quantitative Methods · Quantitative Biology 2013-06-04 Stephen Montgomery-Smith , Francis J. Schmidt

Breast cancer is a disease that threatens many women's life, thus, early and accurate detection plays a key role in reducing the mortality rate. Mammography stands as the reference technique for breast cancer screening; nevertheless, many…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Juan Zuluaga-Gomez , N. Zerhouni , Z. Al Masry , C. Devalland , C. Varnier

Randomized experiments play a major role in data-driven decision making across many different fields and disciplines. In medicine, for example, randomized controlled trials (RCTs) are the backbone of clinical trial methodology for testing…

Applications · Statistics 2016-08-30 Andrew W. Correia

Two-phase sampling is commonly adopted for reducing cost and improving estimation efficiency. In many two-phase studies, the outcome and some cheap covariates are observed for a large sample in Phase I, and expensive covariates are obtained…

Methodology · Statistics 2025-10-14 Qingning Zhou , Kin Yau Wong

Balancing influential covariates is crucial for valid treatment comparisons in clinical studies. While covariate-adaptive randomization is commonly used to achieve balance, its performance can be inadequate when the number of baseline…

Methodology · Statistics 2024-12-30 Ziqing Guo , Yang Liu , Lucy Xia

The study of almost surely discrete random probability measures is an active line of research in Bayesian nonparametrics. The idea of assuming interaction across the atoms of the random probability measure has recently spurred significant…

Statistics Theory · Mathematics 2025-04-25 Mario Beraha , Raffaele Argiento , Federico Camerlenghi , Alessandra Guglielmi

Scene viewing is used to study attentional selection in complex but still controlled environments. One of the main observations on eye movements during scene viewing is the inhomogeneous distribution of fixation locations: While some parts…

Neurons and Cognition · Quantitative Biology 2018-11-14 Hans A. Trukenbrod , Simon Barthelmé , Felix A. Wichmann , Ralf Engbert

Modern randomization methods in clinical trials are invariably adaptive, meaning that the assignment of the next subject to a treatment group uses the accumulated information in the trial. Some of the recent adaptive randomization methods…

Methodology · Statistics 2024-02-12 Alan R. Vazquez , Weng Kee Wong

Data for several applications in diverse fields can be represented as multiple matrices that are linked across rows or columns. This is particularly common in molecular biomedical research, in which multiple molecular "omics" technologies…

Machine Learning · Statistics 2024-08-02 Eric F. Lock

Statistical matching methods are widely used in the social and health sciences to estimate causal effects using observational data. Often the objective is to find comparable groups with similar covariate distributions in a dataset, with the…

Applications · Statistics 2021-01-19 Felix Bestehorn , Maike Bestehorn , Christian Kirches

Adaptive information sampling approaches enable efficient selection of mobile robot's waypoints through which accurate sensing and mapping of a physical process, such as the radiation or field intensity, can be obtained. This paper analyzes…

Robotics · Computer Science 2021-11-23 Aiman Munir , Ramviyas Parasuraman

Indirect comparisons have been increasingly used to compare data from different sources such as clinical trials and observational data in, e.g., a disease registry. To adjust for population differences between data sources,…

Methodology · Statistics 2021-07-27 Jixian Wang

The importance of exploring a potential integration among surveys has been acknowledged in order to enhance effectiveness and minimize expenses. In this work, we employ the alignment method to combine information from two different surveys…

Methodology · Statistics 2024-04-09 Vasilis Chasiotis , Dimitris Karlis

In recurrent event studies, panel binary data arise when subjects are observed at discrete time points and only the recurrent event status within each observation window is recorded. Such data frequently occur in longitudinal studies due to…

Methodology · Statistics 2025-03-18 Pavithra Hariharan , P. G. Sankaran