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Thermochemistry of gas-phase ion-water clusters together with estimates of the hydration free energy of the clusters and the water ligands are used to calculate the hydration free energy of the ion. Often the hydration calculations use a…

Biological Physics · Physics 2015-05-28 Safir Merchant , Purushottam D. Dixit , Kelsey R. Dean , D. Asthagiri

Studying chemical reactions at very low temperatures is of importance for the understanding of fundamental physical and chemical processes. At very low energies, collisions are dominated by only a few partial waves. Thus, studies in this…

Chemical Physics · Physics 2017-03-30 Dongdong Zhang , Stefan Willitsch

Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression. Parametric and structural uncertainty, as well as…

Molecular Networks · Quantitative Biology 2014-10-15 Ovidiu Radulescu , Alexander N. Gorban , Andrei Zinovyev , Vincent Noel

Electrolytes play an important role in a plethora of applications ranging from energy storage to biomaterials. Notwithstanding this, the structure of concentrated electrolytes remains enigmatic. Many theoretical approaches attempt to model…

Soft Condensed Matter · Physics 2021-04-14 Penelope Jones , Fabian Coupette , Andreas Härtel , Alpha A. Lee

In biology, ligand mediated transitions (LMT), where the binding of a molecular ligand onto the binding site of a receptor molecule leads to a well-defined change in the conformation of the receptor, are often referred to as 'the second…

A method for generating angular forces around $\sigma$-bonded transition metal ions is generalized to treat $\pi$-bonded configurations. The theoretical approach is based on an analysis of a ligand-field Hamiltonian based on the moments of…

Soft Condensed Matter · Physics 2009-10-31 A. E. Carlsson , S. Zapata

Fusion reactions of heavy ions are investigated by employing a simple stochastic semi-classical model which includes the coupling between relative motion and low frequency collective surface modes of colliding ions similarly to the quantal…

Nuclear Theory · Physics 2010-03-19 Sakir Ayik , Bulent Yilmaz , Denis Lacroix

Ion transport in biological tissues is crucial in the study of many biological and pathological problems. Some multi-cellular structures, like smooth muscles on the vessel walls, could be treated as periodic bi-domain structures, which…

Analysis of PDEs · Mathematics 2021-03-11 Chun Xiao , Xingye Yue , Huaxiong Huang , Shixin Xu

Ion transport in concentrated electrolytes plays a fundamental role in electrochemical systems such as lithium ion batteries. Nonetheless, the mechanism of transport amid strong ion-ion interactions remains enigmatic. A key question is…

Soft Condensed Matter · Physics 2022-08-08 Penelope K. Jones , Kara D. Fong , Kristin A. Persson , Alpha A. Lee

Ion channels are specific proteins present in the membranes of living cells. They control the flow of specific ions through a cell, initiated by an ion channel's electrochemical gradient. In doing so, they control important physiological…

Subcellular Processes · Quantitative Biology 2012-09-14 Andrew Das Arulsamy

The features of heavy ion collisions that suggest the relevance of collective dynamics, as opposed to mere superpositions of nucleon-nucleon or even parton-parton collisions, are reviewed. The surprise of these studies is that bulk…

Nuclear Experiment · Physics 2009-11-10 Peter Steinberg

Proteins' fuzziness are features for communicating changes in cell signaling instigated by binding with secondary messengers, such as calcium ions, associated with the coordination of muscle contraction, neurotransmitter release, and gene…

Quantitative Methods · Quantitative Biology 2024-07-25 Pengzhi Zhang , Jules Nde , Yossi Eliaz , Nathaniel Jennings , Piotr Cieplak , Margaret. S. Cheung

We consider a simple working hypothesis that all permeation properties of open ionic channels can be predicted by understanding electrodiffusion in fixed structures, without invoking conformation changes, or changes in chemical bonds. We…

Biomolecules · Quantitative Biology 2015-03-17 Bob Eisenberg

Ions transiting biomembranes might pass readily from water through ion-specific membrane proteins if those protein channels provide environments similar to the aqueous solution hydration environment. Indeed, bulk aqueous solution is an…

Chemical Physics · Physics 2019-12-10 Mangesh I. Chaudhari , Juan M. Vanegas , L. R. Pratt , Ajay Muralidharan , Susan B. Rempe

We introduce a statistical and linear response theory of selective conduction in biological ion channels with multiple binding sites and possible point mutations. We derive an effective grand-canonical ensemble and generalised Einstein…

Biological Physics · Physics 2021-06-02 W. A. T. Gibby , M. L. Barabash , C. Guardiani , D. G. Luchinsky , P. V. E. McClintock

A simple "trick" is proposed, which allows to perform exactly the site-averaging procedure required when developing integral equation theories of interaction site models of macromolecular fluids. It shows that no approximation is involved…

Soft Condensed Matter · Physics 2007-05-23 V. Krakoviack

In this paper, we consider the problem of model order reduction of stochastic biochemical networks. In particular, we reduce the order of (the number of equations in) the Linear Noise Approximation of the Chemical Master Equation, which is…

Optimization and Control · Mathematics 2014-03-25 Aivar Sootla , James Anderson

We develop a model of molecular binding based on the Bohr-Sommerfeld description of atoms together with a constraint taken from conventional quantum mechanics. The model can describe the binding energy curves of H2, H3 and other molecules…

Chemical Physics · Physics 2009-11-11 Anatoly A. Svidzinsky , Siu A. Chin , Marlan O. Scully

We explore an idealized theoretical model for the transport of ions within highly asymmetric ionic liquid mixtures. A primitive model (PM)-inspired system serves as a representative for asymmetric ionic materials (such as liquid crystalline…

In concentrated electrolytes with asymmetric or irregular ions, such as ionic liquids and solvent-in-salt electrolytes, ion association is more complicated than simple ion-pairing. Large branched aggregates can form at significant…