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Supervised machine learning (ML) is used extensively in biology and deserves closer scrutiny. The DOME recommendations aim to enhance the validation and reproducibility of ML research by establishing standards for key aspects such as data…

Novel technologies in genomics allow creating data in exascale dimension with relatively minor effort of human and laboratory and thus monetary resources compared to capabilities only a decade ago. While the availability of this data…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-10 Sandra Gesing , Thomas Richard Connor , Ian Taylor

Increasingly sophisticated experiments, coupled with large-scale computational models, have the potential to systematically test biological hypotheses to drive our understanding of multicellular systems. In this short review, we explore key…

Quantitative Methods · Quantitative Biology 2019-10-28 Paul Macklin

Materials science is becoming increasingly more reliant on digital data to facilitate progress in the field. Due to a large diversity in its scope, breadth, and depth, organizing the data in a standard way to optimize the speed and creative…

Materials Science · Physics 2019-03-01 Timur Bazhirov

Data sharing by researchers is a centerpiece of Open Science principles and scientific progress. For a sample of 6019 researchers, we analyze the extent/frequency of their data sharing. Specifically, the relationship with the following four…

Digital Libraries · Computer Science 2021-01-15 Pablo Dorta-González , Sara M. González-Betancor , María Isabel Dorta-González

Software systems are a significant contributor to global sustainability concerns, demanding that environmental, social, technical, and economic factors be systematically addressed from the initial requirements engineering phase. Although…

Software Engineering · Computer Science 2025-10-13 Mandira Roy , Novarun Deb , Nabendu Chaki , Agostino Cortesi

OpenData movement around the globe is demanding more access to information which lies locked in public or private servers. As recently reported by a McKinsey publication, this data has significant economic value, yet its release has…

Databases · Computer Science 2012-05-15 David Leoni

Modern tools for biological research, especially microscopy, have rapidly advanced in recent years, which has led to the generation of increasingly large amounts of data on a regular basis. The result is that scientists desperately need…

Other Quantitative Biology · Quantitative Biology 2021-08-18 Andrey Andreev , Tom Morrell , Kristin Briney , Sandra Gesing , Uri Manor

The reuse of research software is central to research efficiency and academic exchange. The application of software enables researchers with varied backgrounds to reproduce, validate, and expand upon study findings. Furthermore, the…

Measuring the statistical dependence between observed signals is a primary tool for scientific discovery. However, biological systems often exhibit complex non-linear interactions that currently cannot be captured without a priori knowledge…

Knowledge bases are prevalent in various domains and have been widely used in a large number of real applications such as applications in online encyclopedia, social media, biomedical fields, bibliographical networks. Due to their great…

Databases · Computer Science 2021-07-09 Feixiang Wang , Yixiang Fang , Yan Song , Shuang Li , Xinyun Chen

The growing expanse of e-commerce and the widespread availability of online databases raise many fears regarding loss of privacy and many statistical challenges. Even with encryption and other nominal forms of protection for individual…

Statistics Theory · Mathematics 2007-06-13 Stephen E. Fienberg

Data quality is vital for user experience in products reliant on data. As solutions for data quality problems, researchers have developed various taxonomies for different types of issues. However, although some of the existing taxonomies…

Databases · Computer Science 2024-05-28 Qiaolin Qin , Heng Li , Ettore Merlo

Growing privacy regulations and internal governance mandates are driving demand for fine-grained, context-sensitive access control in data management systems. Among competing approaches, content-based access control -- where access…

Databases · Computer Science 2026-04-20 Ahana Pradhan , Srinivas Karthik , Imtiyazuddin Shaik , Srinivas Vivek

This paper explores the application of functional data analysis (FDA) as a means to study the dynamics of software evolution in the open source context. Several challenges in analyzing the data from software projects are discussed, an…

Statistics Theory · Mathematics 2007-06-13 Katherine J. Stewart , David P. Darcy , Sherae L. Daniel

Confidential administrative data is usually only available to researchers within a trusted research environment (TRE). Recently, some UK groups have proposed that low-fidelity synthetic data (LFSD) is available to researchers outside the…

Applications · Statistics 2025-03-19 Gillian M Raab , Sophie McCall , Liam Cavin

Capabilities to exchange health information are critical to accelerate discovery and its diffusion to healthcare practice. However, the same ethical and legal policies that protect privacy hinder these data exchanges, and the issues…

Computers and Society · Computer Science 2016-12-16 Hanna Suominen , Henning Müller , Lucila Ohno-Machado , Sanna Salanterä , Günter Schreier , Leif Hanlen

In recent years, data science has become an indispensable part of our society. Over time, we have become reliant on this technology because of its opportunity to gain value and new insights from data in any field - business, socializing,…

Computers and Society · Computer Science 2020-10-28 Dinh-An Ho , Oya Beyan

Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and postgenomics data sets. Indeed, biological entities are not isolated, but are components of complex…

Quantitative Methods · Quantitative Biology 2018-05-07 Alex White , Matthieu Vignes

As the amount of scientific data continues to grow at ever faster rates, the research community is increasingly in need of flexible computational infrastructure that can support the entirety of the data science lifecycle, including…

Computers and Society · Computer Science 2016-04-12 Robert L. Grossman , Allison Heath , Mark Murphy , Maria Patterson , Walt Wells
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