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Learning personalized cancer treatment with machine learning holds great promise to improve cancer patients' chance of survival. Despite recent advances in machine learning and precision oncology, this approach remains challenging as…

Machine Learning · Computer Science 2022-07-12 Mingyu Lu , Yifang Chen , Su-In Lee

In supervised learning, acquiring labeled training data for a predictive model can be very costly, but acquiring a large amount of unlabeled data is often quite easy. Active learning is a method of obtaining predictive models with high…

Machine Learning · Computer Science 2020-12-17 Hideitsu Hino

We study the problem of learning to choose from m discrete treatment options (e.g., news item or medical drug) the one with best causal effect for a particular instance (e.g., user or patient) where the training data consists of passive…

Machine Learning · Statistics 2017-08-02 Nathan Kallus

INTRODUCTION: The pharmacological treatment of Major Depressive Disorder (MDD) relies on a trial-and-error approach. We introduce an artificial intelligence (AI) model aiming to personalize treatment and improve outcomes, which was deployed…

The stochastic multi-armed bandit problem is a well-known model for studying the exploration-exploitation trade-off. It has significant possible applications in adaptive clinical trials, which allow for dynamic changes in the treatment…

Machine Learning · Computer Science 2019-06-11 Hossein Aboutalebi , Doina Precup , Tibor Schuster

Improving performance in multiple domains is a challenging task, and often requires significant amounts of data to train and test models. Active learning techniques provide a promising solution by enabling models to select the most…

Machine Learning · Computer Science 2023-04-14 Anand Gokul Mahalingam , Aayush Shah , Akshay Gulati , Royston Mascarenhas , Rakshitha Panduranga

Active learning holds promise of significantly reducing data annotation costs while maintaining reasonable model performance. However, it requires sending data to annotators for labeling. This presents a possible privacy leak when the…

Machine Learning · Computer Science 2019-03-28 Oluwaseyi Feyisetan , Thomas Drake , Borja Balle , Tom Diethe

Digital educational technologies offer the potential to customize students' experiences and learn what works for which students, enhancing the technology as more students interact with it. We consider whether and when attempting to discover…

Artificial Intelligence · Computer Science 2023-09-07 ZhaoBin Li , Luna Yee , Nathaniel Sauerberg , Irene Sakson , Joseph Jay Williams , Anna N. Rafferty

Data-driven individualized decision making has recently received increasing research interests. Most existing methods rely on the assumption of no unmeasured confounding, which unfortunately cannot be ensured in practice especially in…

Methodology · Statistics 2022-12-26 Zhengling Qi , Rui Miao , Xiaoke Zhang

In the stochastic linear contextual bandit setting there exist several minimax procedures for exploration with policies that are reactive to the data being acquired. In practice, there can be a significant engineering overhead to deploy…

Machine Learning · Computer Science 2021-07-26 Andrea Zanette , Kefan Dong , Jonathan Lee , Emma Brunskill

We propose a methodology for estimating human behaviors in psychotherapy sessions using mutli-label and multi-task learning paradigms. We discuss the problem of behavioral coding in which data of human interactions is the annotated with…

Computation and Language · Computer Science 2020-10-07 James Gibson , David C. Atkins , Torrey Creed , Zac Imel , Panayiotis Georgiou , Shrikanth Narayanan

In recent years, instructional practices in Operations Research (OR), Management Science (MS), and Analytics have increasingly shifted toward digital environments, where large and diverse groups of learners make it difficult to provide…

Machine Learning · Statistics 2026-03-12 Lukas De Kerpel , Arthur Thuy , Dries F. Benoit

We present an approach to Intelligent Tutoring Systems which adaptively personalizes sequences of learning activities to maximize skills acquired by students, taking into account the limited time and motivational resources. At a given point…

Artificial Intelligence · Computer Science 2019-07-17 Benjamin Clement , Didier Roy , Pierre-Yves Oudeyer , Manuel Lopes

A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be…

Machine Learning · Statistics 2016-07-07 Yingfei Wang , Warren Powell

Delivering treatment recommendations via pervasive electronic devices such as mobile phones has the potential to be a viable and scalable treatment medium for long-term health behavior management. But active experimentation of treatment…

Information Retrieval · Computer Science 2020-08-24 Mawulolo K. Ameko , Miranda L. Beltzer , Lihua Cai , Mehdi Boukhechba , Bethany A. Teachman , Laura E. Barnes

In clinical practice, physicians make a series of treatment decisions over the course of a patient's disease based on his/her baseline and evolving characteristics. A dynamic treatment regime is a set of sequential decision rules that…

Methodology · Statistics 2015-02-04 Phillip J. Schulte , Anastasios A. Tsiatis , Eric B. Laber , Marie Davidian

Some of the most severe bottlenecks preventing widespread development of machine learning models for human behavior include a dearth of labeled training data and difficulty of acquiring high quality labels. Active learning is a paradigm for…

The sequential treatment decisions made by physicians to treat chronic diseases are formalized in the statistical literature as dynamic treatment regimes. To date, methods for dynamic treatment regimes have been developed under the…

Methodology · Statistics 2022-02-22 Janie Coulombe , Erica E. M. Moodie , Susan M. Shortreed , Christel Renoux

Individualized treatment rules aim to identify if, when, which, and to whom treatment should be applied. A globally aging population, rising healthcare costs, and increased access to patient-level data have created an urgent need for…

Methodology · Statistics 2019-01-04 Ying-Qi Zhao , Eric B. Laber , Yang Ning , Sumona Saha , Bruce Sands

In randomized trials involving multiple treatments, bivariate survival outcomes present significant analytical challenges for making decisions. This paper addresses the problem of deriving optimal individualized treatment rules to maximize…

Machine Learning · Statistics 2026-05-29 Kun Ren , Yifan Cui , Wen Su