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Many methods have been developed for finding the commonalities between different organisms to study their phylogeny. The structure of metabolic networks also reveal valuable insights into metabolic capacity of species as well as into the…

Molecular Networks · Quantitative Biology 2016-04-08 Krishanu Deyasi , Anirban Banerjee , Bony Deb

The reconstruction of a species tree from genomic data faces a double hurdle. First, the (gene) tree describing the evolution of each gene may differ from the species tree, for instance, due to incomplete lineage sorting. Second, the…

Populations and Evolution · Quantitative Biology 2021-12-07 Sebastien Roch , Mike Steel

Non-linear maps can possess various dynamical behaviors varying from stable steady states and cycles to chaotic oscillations. Most models assume that individuals within a given population are identical ignoring the fundamental role of…

Populations and Evolution · Quantitative Biology 2007-05-23 Georgy P. Karev

Social scientists have long appreciated that relationships between individuals cannot be described from observing a single domain, and that the structure across domains of interaction can have important effects on outcomes of interest…

General Economics · Economics 2020-05-28 Curtis Atkisson , Piotr J. Górski , Matthew O. Jackson , Janusz A. Hołyst , Raissa M. D'Souza

Phylogenetic networks are a generalization of phylogenetic trees to leaf-labeled directed acyclic graphs that represent ancestral relationships between species whose past includes non-tree-like events such as hybridization and horizontal…

Combinatorics · Mathematics 2021-04-13 Janosch Döcker , Simone Linz , Charles Semple

Research on probabilistic models of networks now spans a wide variety of fields, including physics, sociology, biology, statistics, and machine learning. These efforts have produced a diverse ecology of models and methods. Despite this…

Machine Learning · Statistics 2014-11-18 Abigail Z. Jacobs , Aaron Clauset

We simulate the evolution of model protein sequences subject to mutations. A mutation is considered neutral if it conserves 1) the structure of the ground state, 2) its thermodynamic stability and 3) its kinetic accessibility. All other…

Statistical Mechanics · Physics 2007-05-23 Ugo Bastolla , H. Eduardo Roman , Michele Vendruscolo

The evolution of molecular and phenotypic traits is commonly modelled using Markov processes along a phylogeny. This phylogeny can be a tree, or a network if it includes reticulations, representing events such as hybridization or admixture.…

Populations and Evolution · Quantitative Biology 2024-08-28 Benjamin Teo , Paul Bastide , Cécile Ané

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

Populations and Evolution · Quantitative Biology 2025-09-03 S M Rafiuddin

Mutualistic networks have been shown to involve complex patterns of interactions among animal and plant species. The architecture of these webs seems to pervade some of their robust and fragile behaviour. Recent work indicates that there is…

Populations and Evolution · Quantitative Biology 2016-12-07 Sergi Valverde , Jose Montoya , Lucas Joppa , Ricard Sole

In evolutionary biology, genetic sequences carry with them a trace of the underlying tree that describes their evolution from a common ancestral sequence. The question of how many sequence sites are required to recover this evolutionary…

Populations and Evolution · Quantitative Biology 2008-06-17 Mareike Fischer , Mike Steel

It is generally accepted that "diversity" is associated with success in evolutionary algorithms. However, diversity is a broad concept that can be measured and defined in a multitude of ways. To date, most evolutionary computation research…

Neural and Evolutionary Computing · Computer Science 2023-01-18 Jose Guadalupe Hernandez , Alexander Lalejini , Emily Dolson

In this paper we study group-based Markov models of evolution and their mixtures. In the algebreo-geometric setting, group-based phylogenetic tree models correspond to toric varieties, while their mixtures correspond to secant and join…

Populations and Evolution · Quantitative Biology 2018-11-26 Hector Baños , Nathaniel Bushek , Ruth Davidson , Elizabeth Gross , Pamela E. Harris , Robert Krone , Colby Long , Allen Stewart , Robert Walker

This work focuses on clustering populations with a hierarchical dependency structure that can be described by a tree. A particular example that is the focus of our work is the phylogenetic tree, with nodes often representing biological…

Methodology · Statistics 2023-02-28 Hanxi Sun , Heejung Shim , Vinayak Rao

Phylogenomics heavily relies on well-curated sequence data sets that consist, for each gene, exclusively of 1:1-orthologous. Paralogs are treated as a dangerous nuisance that has to be detected and removed. We show here that this severe…

Discrete Mathematics · Computer Science 2017-12-19 Marc Hellmuth , Nicolas Wieseke , Marcus Lechner , Hans-Peter Lenhof , Martin Middendorf , Peter F. Stadler

In many data-driven applications, collecting data from different sources is increasingly desirable for enhancing performance. In this paper, we are interested in the problem of probabilistic forecasting with multi-source time series. We…

Machine Learning · Computer Science 2023-02-23 Tian Guo

Mixture model-based frameworks are very popular for statistical inference in clustering. While convenient for producing probabilistic estimates of cluster assignments and uncertainty, they are prone to misspecification, which can lead to…

Statistics Theory · Mathematics 2026-05-15 Yu Zheng , Leo L. Duan , Arkaprava Roy

We consider the estimation of the mixing distribution of a normal distribution where both the shift and scale are unobserved random variables. We argue that in general, the model is not identifiable. We give an elegant non-constructive…

Statistics Theory · Mathematics 2024-08-20 Ya'acov Ritov

We show that the protein-protein interaction networks can be surprisingly well described by a very simple evolution model of duplication and divergence. The model exhibits a remarkably rich behavior depending on a single parameter, the…

Molecular Networks · Quantitative Biology 2009-11-10 I. Ispolatov , P. L. Krapivsky , A. Yuryev