Related papers: Spontaneous sarcomere dynamics
A general FitzHugh-Rinzel model, able to describe several neuronal phenomena, is considered. Linear stability and Hopf bifurcations are investigated by means of the spectral equation for the ternary autonomous dynamical system and the…
The motility of a cell can be triggered or inhibited not only by an applied force but also by a mechanically neutral force couple. This type of loading, represented by an applied stress and commonly interpreted as either squeezing or…
The mitotic spindle lies at the heart of the spatio-temporal control over cellular components during cell division. The spindle consists of microtubules, which are not only crosslinked by motor proteins but also by passive binding proteins.…
Magnetic skyrmions exhibit unique, technologically relevant pseudo-particle behaviors which arise from their topological protection, including well-defined, three-dimensional dynamic modes that occur at microwave frequencies. During dynamic…
Spike-timing dependent plasticity (STDP) is an organizing principle of biological neural networks. While synchronous firing of neurons is considered to be an important functional block in the brain, how STDP shapes neural networks possibly…
Actomyosin networks are major structural components of the cell. They provide mechanical integrity and allow dynamic remodeling of eukaryotic cells, self-organizing into the diverse patterns essential for development. We provide a…
Large networks of spiking neurons show abrupt changes in their collective dynamics resembling phase transitions studied in statistical physics. An example of this phenomenon is the transition from irregular, noise-driven dynamics to…
Magnetic skyrmions are topological magnetic spin structures exhibiting particle-like behaviour. They are of strong interest from a fundamental viewpoint and for application, where they have potential to act as information carriers in future…
Cellular migration is crucial for biological processes including embryonic development, immune response, and wound healing. The myosin-clutch model is a framework that describes how cells control migration through the interactions between…
Bifurcation analysis of dynamic pull-in for a lumped mass model is presented. The restoring force of the spring is derived based on the nonlinear constitutive stress-strain law and the driving force of the mass attached to the spring is…
We report on the dynamics of a model frictional system submitted to minute external perturbations. The system consists of a chain of sliders connected through elastic springs that rest on an incline. By introducing cyclic expansions and…
Calcium activation of striated muscle is known to exhibit a strongly cooperative dependency on calcium. Because the calcium receptor protein, troponin (Tn) is known to bind calcium non-cooperatively and has yet to be linked to a cooperative…
Oscillations represent a ubiquitous phenomenon in biological systems. The conventional models of biological periodic oscillations are usually proposed as interconnecting transcriptional feedback loops. Some specific proteins function as…
The onset of frictional motion is mediated by rupture-like slip fronts, which nucleate locally and propagate eventually along the entire interface causing global sliding. The static friction coefficient is a macroscopic measure of the…
Single-molecule atomic force spectroscopy probes elastic properties of titin, ubiquitin and other relevant proteins. We explain bioprotein folding dynamics under both length- and force-clamp by modeling polyprotein modules as particles in a…
Rapid action potential generation --- spiking --- and alternating intervals of spiking and quiescence --- bursting --- are two dynamic patterns observed in neuronal activity. In computational models of neuronal systems, the transition from…
We study the weakly nonlinear saturation of the flutter instability of a planar Cosserat rod in a viscous fluid driven by a terminal follower force. This instability, established in our preceding work as a Hopf bifurcation of a…
In this work, we study in detail the distribution of stochastic forces generated by the molecular motors activity, in the actin cortex of pre-muscular cells. By combining active and passive rheology experiments, performed on the same…
Active processes drive and guide biological dynamics across scales -- from subcellular cytoskeletal remodelling, through tissue development in embryogenesis, to population-level bacterial colonies expansion. In each of these, biological…
Motor-driven cargo transport is a complex phenomenon where multiple motor proteins attached on to a cargo engage in pulling activity, often leading to tug-of-war, displaying bidirectional motion. However, most mathematical and computational…