Related papers: Forensic Identification: Database likelihood ratio…
While the individuals chosen for a genome-wide association study (GWAS) may not be closely related to each other, there can be distant (cryptic) relationships that confound the evidence of disease association. These cryptic relationships…
Discrimination discovery from data is an important task aiming at identifying patterns of illegal and unethical discriminatory activities against protected-by-law groups, e.g., ethnic minorities. While any legally-valid proof of…
This paper introduces a comprehensive database for research and investigation on the effects of inheritance on handwriting. A database has been created that can be used to answer questions such as: Is there a genetic component to…
The Jaccard similarity index has often been employed in science and technology as a means to quantify the similarity between two sets. When modified to operate on real-valued values, the Jaccard similarity index can be applied to compare…
We propose a family of very efficient hierarchical indexing schemes for ungapped, score matrix-based similarity search in large datasets of short (4-12 amino acid) protein fragments. This type of similarity search has importance in both…
Visual kinship recognition aims to identify blood relatives from facial images. Its practical application-- like in law-enforcement, video surveillance, automatic family album management, and more-- has motivated many researchers to put…
For several decades, legal and scientific scholars have argued that conclusions from forensic examinations should be supported by statistical data and reported within a probabilistic framework. Multiple models have been proposed to quantify…
The kernel exponential family is a rich class of distributions, which can be fit efficiently and with statistical guarantees by score matching. Being required to choose a priori a simple kernel such as the Gaussian, however, limits its…
Populations of isogenic embryonic stem cells or clonal bacteria often exhibit extensive phenotypic heterogeneity which arises from stochastic intrinsic dynamics of cells. The internal state of the cell can be transmitted epigenetically in…
Automatic kinship verification aims to determine whether some individuals belong to the same family. It is of great research significance to help missing persons reunite with their families. In this work, the challenging problem is…
Nearest-neighbor search, which returns the nearest neighbor of a query point in a set of points, is an important and widely studied problem in many fields, and it has wide range of applications. In many of them, such as sensor databases,…
Existence of incomplete and imprecise data has moved the database paradigm from deterministic to proba- babilistic information. Probabilistic databases contain tuples that may or may not exist with some probability. As a result, the number…
Since most analysis software for genome-wide association studies (GWAS) currently exploit only unrelated individuals, there is a need for efficient applications that can handle general pedigree data or mixtures of both population and…
We propose a method to identify all the nodes that are relevant to compute all the conditional probability distributions for a given set of nodes. Our method is simple, effcient, consistent, and does not require learning a Bayesian network…
Pedigree graphs, or family trees, are typically constructed by an expensive process of examining genealogical records to determine which pairs of individuals are parent and child. New methods to automate this process take as input genetic…
In this paper we explore the possibility of using bibliographic databases for tracking the geographic origin of surnames. Surnames are used as a proxy to determine the ethnic, genetic or geographic origin of individuals in many fields such…
For most of the important processes in DNA metabolism, a protein has to reach a specific binding site on the DNA. The specific binding site may consist of just a few base pairs while the DNA is usually several millions of base pairs long.…
DNA fingerprinting is a cornerstone for human identification in forensics, where the sequence of highly polymorphic short tandem repeats (STRs) from an individual is compared against a DNA database. This presents significant privacy risks…
With the reduction of sequencing costs and the pervasiveness of computing devices, genomic data collection is continually growing. However, data collection is highly fragmented and the data is still siloed across different repositories.…
We linked names and contact information to publicly available profiles in the Personal Genome Project. These profiles contain medical and genomic information, including details about medications, procedures and diseases, and demographic…