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We consider the problem of self tolerance in the frame of a minimalistic model of the idiotypic network. A node of this network represents a population of B lymphocytes of the same idiotype which is encoded by a bit string. The links of the…

Cell Behavior · Quantitative Biology 2013-08-30 Robert Schulz , Benjamin Werner , Ulrich Behn

We present a model for the evolution of networks of occupied sites on undirected regular graphs. At every iteration step in a parallel update I randomly chosen empty sites are occupied and occupied sites having degree outside of a given…

Statistical Mechanics · Physics 2009-11-07 M. Brede , U. Behn

We consider a minimalistic dynamic model of the idiotypic network of B-lymphocytes. A network node represents a population of B-lymphocytes of the same specificity (idiotype), which is encoded by a bitstring. The links of the network…

Cell Behavior · Quantitative Biology 2015-06-03 Holger Schmidtchen , Mario Thüne , Ulrich Behn

We consider self-tolerance and its failure -autoimmunity- in a minimal mathematical model of the idiotypic network. A node in the network represents a clone of B-lymphocytes and its antibodies of the same idiotype which is encoded by a…

Cell Behavior · Quantitative Biology 2016-09-20 Stefan Landmann , Nicolas Preuss , Ulrich Behn

In this paper, we propose an evolving network model growing fast in units of module, based on the analysis of the evolution characteristics in real complex networks. Each module is a small-world network containing several interconnected…

Physics and Society · Physics 2011-10-11 Zou Zhi-Yun , Liu Peng , Lei Li , Gao Jian-Zhi

We investigate a model where idiotypes (characterizing B-lymphocytes and antibodies of an immune system) and anti-idiotypes are represented by complementary bitstrings of a given length d allowing for a number of mismatches (matching…

Biological Physics · Physics 2009-11-06 Markus Brede , Ulrich Behn

If the behavior of a system with many degrees of freedom can be captured by a small number of collective variables, then plausibly there is an underlying mean-field theory. We show that simple versions of this idea fail to describe the…

Biological Physics · Physics 2025-04-22 Luca Di Carlo , Francesca Mignacco , Christopher W. Lynn , William Bialek

We model recruitment in adaptive social networks in the presence of birth and death processes. Recruitment is characterized by nodes changing their status to that of the recruiting class as a result of contact with recruiting nodes. Only a…

Populations and Evolution · Quantitative Biology 2012-07-20 Maxim S. Shkarayev , Ira B. Schwartz , Leah B. Shaw

A network is said to have the properties of a small world if a suitably defined average distance between any two nodes is proportional to the logarithm of the number of nodes, $N$. In this paper, we present a novel derivation of the…

Statistical Mechanics · Physics 2022-10-26 Andrew D. Jackson , Subodh P. Patil

Clustering is the propensity of nodes that share a common neighbour to be connected. It is ubiquitous in many networks but poses many modelling challenges. Clustering typically manifests itself by a higher than expected frequency of…

Dynamical Systems · Mathematics 2016-01-07 Martin Ritchie , Luc Berthouze , Istvan Z. Kiss

We introduce a model of randomly connected neural populations and study its dynamics by means of the dynamical mean-field theory and simulations. Our analysis uncovers a rich phase diagram, featuring high- and low-dimensional chaotic…

Biological Physics · Physics 2025-05-01 Łukasz Kuśmierz , Ulises Pereira-Obilinovic , Zhixin Lu , Dana Mastrovito , Stefan Mihalas

We study binary state dynamics on a network where each node acts in response to the average state of its neighborhood. Allowing varying amounts of stochasticity in both the network and node responses, we find different outcomes in random…

Physics and Society · Physics 2014-07-09 Kameron Decker Harris , Christopher M. Danforth , Peter Sheridan Dodds

The spread of an epidemic disease and the population's collective behavioural response are deeply intertwined, influencing each other's evolution. Such a co-evolution typically has been overlooked in mathematical models, limiting their…

Dynamical Systems · Mathematics 2024-10-24 Kathinka Frieswijk , Lorenzo Zino , Mengbin Ye , Alessandro Rizzo , Ming Cao

We use the annealed formulation of complex networks to study the dynamical behavior of disease spreading on both static and adaptive networked systems. This unifying approach relies on the annealed adjacency matrix, representing one network…

Physics and Society · Physics 2010-11-09 Beniamino Guerra , Jesus Gomez-Gardenes

Collective dynamics on small-world networks emerge in a broad range of systems with their spectra characterizing fundamental asymptotic features. Here we derive analytic mean field predictions for the spectra of small-world models that…

Physics and Society · Physics 2015-06-30 Carsten Grabow , Stefan Grosskinsky , Marc Timme

We study the mean-field limit of a generic class of dynamic co-evolving latent space networks motivated by the social and opinion dynamics literature. Such models include $n$ agents, whose opinions are given by latent stochastic processes,…

Probability · Mathematics 2026-04-24 Ankan Ganguly , Konstantinos Spiliopoulos , Daniel Sussman

Modularity is a widely used measure for evaluating community structure in networks. The definition of modularity involves a comparison of within-community edges in the observed network and that number in an equivalent randomized network.…

Social and Information Networks · Computer Science 2013-02-13 Xin Liu , Tsuyoshi Murata , Ken Wakita

Mean field theory is a device to analyze the collective behavior of a dynamical system comprising many interacting particles. The theory allows to reduce the behavior of the system to the properties of a handful of parameters. In neural…

Neurons and Cognition · Quantitative Biology 2022-06-10 Giancarlo La Camera

We study binary state contagion dynamics on a social network where nodes act in response to the average state of their neighborhood. We model the competing tendencies of imitation and non-conformity by incorporating an off-threshold into…

Physics and Society · Physics 2015-03-13 Kameron Decker Harris

The mechanisms by which modularity emerges in complex networks are not well understood but recent reports have suggested that modularity may arise from evolutionary selection. We show that finding the modularity of a network is analogous to…

Disordered Systems and Neural Networks · Physics 2009-11-10 Roger Guimera , Marta Sales-Pardo , Luis A. N. Amaral
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