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Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in…

In computer vision, image segmentation is always selected as a major research topic by researchers. Due to its vital rule in image processing, there always arises the need of a better image segmentation method. Clustering is an unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2015-06-08 Dibya Jyoti Bora , Anil Kumar Gupta

Automatic polyp segmentation is crucial for effective diagnosis and treatment in colonoscopy images. Traditional methods encounter significant challenges in accurately delineating polyps due to limitations in feature representation and the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Quang Vinh Nguyen , Thanh Hoang Son Vo , Sae-Ryung Kang , Soo-Hyung Kim

In this work, we propose a new segmentation algorithm for images containing convex objects present in multiple shapes with a high degree of overlap. The proposed algorithm is carried out in two steps, first we identify the visible contours,…

Computer Vision and Pattern Recognition · Computer Science 2017-11-08 Kumar Abhinav , Jaideep Singh Chauhan , Debasis Sarkar

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

We present cytometric classification of live healthy and cancer cells by using the spatial morphological and textural information found in the label-free quantitative phase images of the cells. We compare both healthy cells to primary tumor…

Quantitative Methods · Quantitative Biology 2020-01-23 Darina Roitshtain , Lauren Wolbromsky , Evgeny Bal , Hayit Greenspan , Lisa L. Satterwhite , Natan T. Shaked

Cell boundary information is crucial for analyzing cell behaviors from time-lapse microscopy videos. Existing supervised cell segmentation tools, such as ImageJ, require tuning various parameters and rely on restrictive assumptions about…

Applications · Statistics 2026-01-27 Laura Baracaldo , Blythe King , Haoran Yan , Yizi Lin , Nina Miolane , Mengyang Gu

This paper introduces k-splits, an improved hierarchical algorithm based on k-means to cluster data without prior knowledge of the number of clusters. K-splits starts from a small number of clusters and uses the most significant data…

Computer Vision and Pattern Recognition · Computer Science 2022-05-25 Seyed Omid Mohammadi , Ahmad Kalhor , Hossein Bodaghi

Parallel algorithms for solving any image processing task is a highly demanded approach in the modern world. Cellular Automata (CA) are the most common and simple models of parallel computation. So, CA has been successfully used in the…

Computer Vision and Pattern Recognition · Computer Science 2014-07-30 Deepak Ranjan Nayak , Prashanta Kumar Patra , Amitav Mahapatra

This paper is directed towards the food crystal quality control area for manufacturing, focusing on efficiently predicting food crystal counts and size distributions. Previously, manufacturers used the manual counting method on microscopic…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Xiaoyu Ji , Jan P Allebach , Ali Shakouri , Fengqing Zhu

Detecting elliptical objects from an image is a central task in robot navigation and industrial diagnosis where the detection time is always a critical issue. Existing methods are hardly applicable to these real-time scenarios of limited…

Computer Vision and Pattern Recognition · Computer Science 2017-08-02 Qi Jia , Xin Fan , Zhongxuan Luo , Lianbo Song , Tie Qiu

Fitting concentric geometric objects to digitized data is an important problem in many areas such as iris detection, autonomous navigation, and industrial robotics operations. There are two common approaches to fitting geometric shapes to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Ali A. Al-Sharadqah , Lorenzo Rull

The performance of image segmentation highly relies on the original inputting image. When the image is contaminated by some noises or blurs, we can not obtain the efficient segmentation result by using direct segmentation methods. In order…

Optimization and Control · Mathematics 2016-05-31 Baoli Shi , Zhi-Feng Pang , Jing Xu

Advanced image segmentation and processing tools present an opportunity to study cell processes and their dynamics. However, image analysis is often routine and time-consuming. Nowadays, alternative data-driven approaches using deep…

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

Quantitative Methods · Quantitative Biology 2019-04-24 Weikang Wang , David A. Taft , Yi-Jiun Chen , Jingyu Zhang , Callen T. Wallace , Min Xu , Simon C. Watkins , Jianhua Xing

The elliptical shape prior information plays a vital role in improving the accuracy of image segmentation for specific tasks in medical and natural images. Existing deep learning-based segmentation methods, including the Segment Anything…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Xinyu Zhao , Jun Liu , Faqiang Wang , Li Cui , Yuping Duan

Most existing methods handle cell instance segmentation problems directly without relying on additional detection boxes. These methods generally fails to separate touching cells due to the lack of global understanding of the objects. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Jingru Yi , Pengxiang Wu , Qiaoying Huang , Hui Qu , Bo Liu , Daniel J. Hoeppner , Dimitris N. Metaxas

In this work, we describe a method for large-scale 3D cell-tracking through a segmentation selection approach. The proposed method is effective at tracking cells across large microscopy datasets on two fronts: (i) It can solve problems…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Jordão Bragantini , Merlin Lange , Loïc Royer

Cell detection and counting in the image-based ELISPOT and Fluorospot immunoassays is considered a bottleneck. The task has remained hard to automatize, and biomedical researchers often have to rely on results that are not accurate.…

Image and Video Processing · Electrical Eng. & Systems 2018-10-24 Pol del Aguila Pla , Joakim Jaldén