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Related papers: Evolutionary Stability Against Multiple Mutations

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Evolutionarily stable strategy (ESS) is an important solution concept in game theory which has been applied frequently to biological models. Informally an ESS is a strategy that if followed by the population cannot be taken over by a…

Computer Science and Game Theory · Computer Science 2019-01-18 Sam Ganzfried

Robustness to genetic or environmental disturbances is often considered as a key property of living systems. Yet, in spite of being discussed since the 1950s, how robustness emerges from the complexity of genetic architectures and how it…

Populations and Evolution · Quantitative Biology 2022-03-31 Arnaud Le Rouzic

Antibiotic resistance is a growing public health problem. To gain a fundamental understanding of resistance evolution, a combination of systematic experimental and theoretical approaches is required. Evolution experiments combined with…

Populations and Evolution · Quantitative Biology 2021-05-24 Gabriela Petrungaro , Yuval Mulla , Tobias Bollenbach

BACKGROUND: An important question is whether evolution favors properties such as mutational robustness or evolvability that do not directly benefit any individual, but can influence the course of future evolution. Functionally similar…

Populations and Evolution · Quantitative Biology 2009-04-16 Jesse D. Bloom , Zhongyi Lu , David Chen , Alpan Raval , Ophelia S. Venturelli , Frances H. Arnold

Here, we address the essential question of whether, in the context of evolving populations, ecosystems attain properties that enable persistence of the ecosystem itself. We use a simple ecosystem model describing resource, producer, and…

Populations and Evolution · Quantitative Biology 2014-07-29 Jarad P. Mellard , Ford Ballantyne

This paper aims to provide a thorough study on the effectiveness of the transformation-based ensemble defence for image classification and its reasons. It has been empirically shown that they can enhance the robustness against evasion…

Machine Learning · Computer Science 2020-10-09 Chang Liao , Yao Cheng , Chengfang Fang , Jie Shi

The functioning of many biochemical networks is often robust -- remarkably stable under changes in external conditions and internal reaction parameters. Much recent work on robustness and evolvability has focused on the structure of neutral…

Quantitative Methods · Quantitative Biology 2011-03-15 Bryan C. Daniels , Yan-Jiun Chen , James P. Sethna , Ryan N. Gutenkunst , Christopher R. Myers

The aim of this paper is two-fold. First, we propose a new computational method to investigate the particularities of evolution. Second, we apply this method to a model of gene regulatory networks (GRNs) and explore the evolution of…

Molecular Networks · Quantitative Biology 2022-01-21 Tadamune Kaneko , Macoto Kikuchi

Robustness is widely regarded as a fundamental problem in the analysis of machine learning (ML) models. Most often robustness equates with deciding the non-existence of adversarial examples, where adversarial examples denote situations…

Machine Learning · Computer Science 2023-12-19 Yacine Izza , Joao Marques-Silva

We use the indirect evolutionary approach to study evolutionarily stable preferences against multiple mutations in single- and multi-population matching settings, respectively. Players choose strategies to maximize their subjective…

Computer Science and Game Theory · Computer Science 2025-07-08 Yu-Sung Tu , Wei-Torng Juang

The robustness property of exponential dichotomies refers to the stability of this notion under small linear perturbations. In recent work~\cite{PPX}, the authors have identified a new class of perturbations under which the notion of a…

Dynamical Systems · Mathematics 2025-12-16 Davor Dragicevic

Recent work has shown that expression level is the main predictor of a gene’s evolutionary rate, and that more highly expressed genes evolve slower. A possible explanation for this observation is selection for proteins which fold…

Populations and Evolution · Quantitative Biology 2007-05-23 Claus O. Wilke , D. Allan Drummond

Current research on defending against adversarial examples focuses primarily on achieving robustness against a single attack type such as $\ell_2$ or $\ell_{\infty}$-bounded attacks. However, the space of possible perturbations is much…

Machine Learning · Computer Science 2024-10-10 Sihui Dai , Chong Xiang , Tong Wu , Prateek Mittal

Focusing on the bipartite Stable Marriage problem, we investigate different robustness measures related to stable matchings. We analyze the computational complexity of computing them and analyze their behavior in extensive experiments on…

Computer Science and Game Theory · Computer Science 2024-08-20 Kimon Boehmer , Niclas Boehmer

Phenotype of biological systems needs to be robust against mutation in order to sustain themselves between generations. On the other hand, phenotype of an individual also needs to be robust against fluctuations of both internal and external…

Populations and Evolution · Quantitative Biology 2015-06-26 Kunihiko Kaneko

We suggest to simulate evolution of complex organisms constrained by the sole requirement of robustness in their expression patterns. This scenario is illustrated by evolving discrete logical networks with epigenetic properties. Evidence…

Statistical Mechanics · Physics 2007-05-23 Stefan Bornholdt , Kim Sneppen

Evolution on neutral networks of genotypes has been found in models to concentrate on genotypes with high mutational robustness, to a degree determined by the topology of the network. Here analysis is generalized beyond neutral networks to…

Populations and Evolution · Quantitative Biology 2015-09-01 Lee Altenberg

Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. Assuming small mutation rates, evolution can be predicted based solely on the fitness differences between phenotypes. Predicting an…

Populations and Evolution · Quantitative Biology 2015-03-23 Benedikt Bauer , Chaitanya S. Gokhale

We consider a vaccination game that results with the introduction of premature and possibly scarce vaccines introduced in a desperate bid to combat the otherwise ravaging deadly pandemic. The response of unsure agents amid many…

Dynamical Systems · Mathematics 2021-09-14 Vartika Singh , Khushboo Agarwal , Shubham , Veeraruna Kavitha

We investigate the fitness advantage associated with the robustness of a phenotype against deleterious mutations using deterministic mutation-selection models of quasispecies type equipped with a mesa shaped fitness landscape. We obtain…

Populations and Evolution · Quantitative Biology 2015-05-13 Andrea Wolff , Joachim Krug
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