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Related papers: Stochastic Description of a Bistable Frustrated Un…

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The dynamics of an ensemble of bistable elements with global time-delayed coupling under the influence of noise is studied analytically and numerically. Depending on the noise level the system undergoes ordering transitions and demonstrates…

Statistical Mechanics · Physics 2009-11-10 D. Huber , L. S. Tsimring

Stochastic oscillations in individual cells are usually characterized by a non-monotonic power spectrum with an oscillatory autocorrelation function. Here we develop an analytical approach of stochastic oscillations in a minimal hybrid…

Molecular Networks · Quantitative Biology 2024-02-08 Chen Jia , Hong Qian , Michael Q. Zhang

The proper functioning of multicellular organisms requires the robust establishment of precise proportions between distinct cell-types. This developmental differentiation process typically involves intracellular regulatory and stochastic…

Cell Behavior · Quantitative Biology 2016-06-22 Benjamin Pfeuty , Kunihiko Kaneko

Adaptation to environmental change is a common property of biological systems. Cells initially respond to external changes in the environment, but after some time, they regain their original state. By considering an element consisting of…

Biological Physics · Physics 2015-05-13 Masayo Inoue , Kunihiko Kaneko

Auto-regulatory feedback loops are one of the most common network motifs. A wide variety of stochastic models have been constructed to understand how the fluctuations in protein numbers in these loops are influenced by the kinetic…

Subcellular Processes · Quantitative Biology 2020-04-22 James Holehouse , Zhixing Cao , Ramon Grima

Oscillatory systems with time-delayed pulsatile feedback appear in various applied and theoretical research areas, and received a growing interest in the last years. For such systems, we report a remarkable scenario of destabilization of a…

Chaotic Dynamics · Physics 2015-05-28 Vladimir Klinshov , Leonhard Lücken , Dmitry Shchapin , Vladimir Nekorkin , Serhiy Yanchuk

Gene expression is inherently noisy as many steps in the read-out of the genetic information are stochastic. To disentangle the effect of different sources of stochasticity in such systems, we consider various models that describe some…

Molecular Networks · Quantitative Biology 2015-06-05 Rahul Marathe , David Gomez , Stefan Klumpp

Inside individual cells, expression of genes is stochastic across organisms ranging from bacterial to human cells. A ubiquitous feature of stochastic expression is burst-like synthesis of gene products, which drives considerable…

Molecular Networks · Quantitative Biology 2016-09-13 Pavol Bokes , Abhyudai Singh

We use a multifractal formalism to study the effect of stochastic resonance in a noisy bistable system driven by various input signals. To characterize the response of a stochastic bistable system we introduce a new measure based on the…

Chaotic Dynamics · Physics 2009-10-31 Alexander Silchenko , Chin-Kun Hu

We study a stochastic two-species chemical reaction system with two mechanisms. One mechanism consists of chemical interactions which govern the overall drift of species amounts in the system; the other mechanism consists of resampling,…

Probability · Mathematics 2014-05-06 John K. McSweeney , Lea Popovic

The genetic repressilator circuit consists of three transcription factors, or repressors, which negatively regulate each other in a cyclic manner. This circuit was synthetically constructed on plasmids in {\it Escherichia coli} and was…

Molecular Networks · Quantitative Biology 2009-11-13 Adiel Loinger , Ofer Biham

We study the collective dynamics of noise-driven excitable elements, so-called active rotators. Crucially here, the natural frequencies and the individual coupling strengths are drawn from some joint probability distribution. Combining a…

Disordered Systems and Neural Networks · Physics 2014-08-18 Bernard Sonnenschein , Thomas K. DM. Peron , Francisco A. Rodrigues , Jürgen Kurths , Lutz Schimansky-Geier

Intrinsic or demographic noise has been shown to play an important role in the dynamics of a variety of systems including predator-prey populations, intracellular biochemical reactions, and oscillatory chemical reaction systems, and is…

Statistical Mechanics · Physics 2013-03-14 C. Michael Giver , Bulbul Chakraborty

We analyze a simple stochastic model to describe motor molecules which cooperate in large groups and present a physical mechanism which can lead to oscillatory motion if the motors are elastically coupled to their environment. Beyond a…

Soft Condensed Matter · Physics 2009-10-28 Frank Julicher , Jacques Prost

We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of ``stochastic feedback''. We illustrate this approach by considering the neuroautonomic regulation of the heart…

Statistical Mechanics · Physics 2009-10-30 Plamen Ch. Ivanov , Luis A. N. Amaral , Ary Goldberger , H. Eugene Stanley

Chemical reactions in cell are subject to intense stochastic fluctuations. An important question is how the fundamental physiological behavior of cell is kept stable against those noisy perturbations. In this paper a stochastic model of…

Molecular Networks · Quantitative Biology 2009-11-13 Yurie Okabe , Masaki Sasai

We study the interplay between noise and a positive feedback mechanism in an excitable system that generates events. We show that such a system can exhibit a bistability in the dynamics of the event generation (states of low and high…

Statistical Mechanics · Physics 2014-10-22 Justus A. Kromer , Reynaldo D. Pinto , Benjamin Lindner , Lutz Schimansky-Geier

Feedback in cellular processes is typically inferred through cellular responses to experimental perturbations. Modular response analysis provides a theoretical framework for translating specific perturbations into feedback sensitivities…

Molecular Networks · Quantitative Biology 2025-05-09 Seshu Iyengar , Andreas Hilfinger

Stochastic resonance is a well established phenomenon, which proves relevant for a wide range of applications, of broad trans-disciplinary breath. Consider a one dimensional bistable stochastic system, characterized by a deterministic…

Statistical Mechanics · Physics 2023-10-17 Giuliano Migliorini , Duccio Fanelli

We study a noisy oscillator with pulse delayed feedback, theoretically and in an electronic experimental implementation. Without noise, this system has multiple stable periodic regimes. We consider two types of noise: i) phase noise acting…

Adaptation and Self-Organizing Systems · Physics 2020-08-26 Vladimir Klinshov , Dmitry Shchapin , Otti D'Huys