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This paper presents a novel method for the reconstruction of a neural network connectivity using calcium fluorescence data. We introduce a fast unsupervised method to integrate different networks that reconstructs structural connectivity…

Machine Learning · Statistics 2015-06-02 Pau Bellot , Patrick E. Meyer

Neuronal dynamics are fundamentally constrained by the underlying structural network architecture, yet much of the details of this synaptic connectivity are still unknown even in neuronal cultures in vitro. Here we extend a previous…

Neurons and Cognition · Quantitative Biology 2017-02-08 Javier G. Orlandi , Olav Stetter , Jordi Soriano , Theo Geisel , Demian Battaglia

Deducing the structure of neural circuits is one of the central problems of modern neuroscience. Recently-introduced calcium fluorescent imaging methods permit experimentalists to observe network activity in large populations of neurons,…

Applications · Statistics 2011-07-22 Yuriy Mishchencko , Joshua T. Vogelstein , Liam Paninski

Fluorescent calcium imaging provides a potentially powerful tool for inferring connectivity in neural circuits with up to thousands of neurons. However, a key challenge in using calcium imaging for connectivity detection is that current…

Information Theory · Computer Science 2014-09-05 Alyson K. Fletcher , Sundeep Rangan

Brain science is an evolving research area inviting great enthusiasm with its potential for providing insights and thereby, preventing, and treating multiple neuronal disorders affecting millions of patients. Discovery of relationships,…

Neurons and Cognition · Quantitative Biology 2016-03-17 Bisakha Ray , Alexander V. Alekseyenko , Sisi Ma , Alexander Statnikov , Constantin Aliferis

In this paper we estimate the propagation of liquidity shocks through interbank markets when the information about the underlying credit network is incomplete. We show that techniques such as Maximum Entropy currently used to reconstruct…

Risk Management · Quantitative Finance 2013-10-08 Iacopo Mastromatteo , Elia Zarinelli , Matteo Marsili

Dynamics and function of neuronal networks are determined by their synaptic connectivity. Current experimental methods to analyze synaptic network structure on the cellular level, however, cover only small fractions of functional neuronal…

Neurons and Cognition · Quantitative Biology 2015-07-28 Yury V. Zaytsev , Abigail Morrison , Moritz Deger

Understanding brain dynamics and functions critically depends on knowledge of the network connectivity among neurons. However, the complexity of brain structural connectivity, coupled with continuous modifications driven by synaptic…

Neurons and Cognition · Quantitative Biology 2025-07-04 Kai Chen , Mingzhang Wang , Songting Li , Douglas Zhou

Convolutional neural networks (CNNs) trained with cross-entropy loss have proven to be extremely successful in classifying images. In recent years, much work has been done to also improve the theoretical understanding of neural networks.…

Statistics Theory · Mathematics 2024-04-30 Michael Kohler , Sophie Langer

We study model recovery for data classification, where the training labels are generated from a one-hidden-layer neural network with sigmoid activations, also known as a single-layer feedforward network, and the goal is to recover the…

Machine Learning · Statistics 2020-05-07 Haoyu Fu , Yuejie Chi , Yingbin Liang

Network topology plays a key role in many phenomena, from the spreading of diseases to that of financial crises. Whenever the whole structure of a network is unknown, one must resort to reconstruction methods that identify the least biased…

Data Analysis, Statistics and Probability · Physics 2015-06-09 Rossana Mastrandrea , Tiziano Squartini , Giorgio Fagiolo , Diego Garlaschelli

Inference of the network structure (e.g., routing topology) and dynamics (e.g., link performance) is an essential component in many network design and management tasks. In this paper we propose a new, general framework for analyzing and…

Networking and Internet Architecture · Computer Science 2019-11-13 Jian Ni , Sekhar Tatikonda

The recent development of genetically encoded calcium indicators enables monitoring in vivo the activity of neuronal populations. Most analysis of these calcium transients relies on linear regression analysis based on the sensory stimulus…

Neurons and Cognition · Quantitative Biology 2014-09-10 Fabrizio De Vico Fallani , Martina Corazzol , Jenna R. Sternberg , Claire Wyart , Mario Chavez

Neural systems can be modeled as networks of functionally connected neural elements. The resulting network can be analyzed using mathematical tools from network science and graph theory to quantify the system's topological organization and…

Neurons and Cognition · Quantitative Biology 2020-07-01 Richard F. Betzel , Katherine C. Wood , Christopher Angeloni , Maria Neimark Geffen , Danielle S. Bassett

Transfer entropy (TE) is an attractive model-free method to detect causality and infer structural connectivity of general digital systems. However it relies on high dimensions used in its definition to clearly remove the memory effect and…

Quantitative Methods · Quantitative Biology 2019-05-13 Zhong-Qi Kyle Tian , Douglas Zhou , David Cai

Reconstructing weighted networks from partial information is necessary in many important circumstances, e.g. for a correct estimation of systemic risk. It has been shown that, in order to achieve an accurate reconstruction, it is crucial to…

Physics and Society · Physics 2017-03-07 Tiziano Squartini , Giulio Cimini , Andrea Gabrielli , Diego Garlaschelli

Graph Convolutional Networks (GCN) are Graph Neural Networks where the convolutions are applied over a graph. In contrast to Convolutional Neural Networks, GCN's are designed to perform inference on graphs, where the number of nodes can…

Machine Learning · Computer Science 2024-06-12 Adrian Moldovan , Angel Caţaron , Răzvan Andonie

Due to the interconnectedness of financial entities, estimating certain key properties of a complex financial system (e.g. the implied level of systemic risk) requires detailed information about the structure of the underlying network.…

Physics and Society · Physics 2020-09-08 Federica Parisi , Tiziano Squartini , Diego Garlaschelli

Many networks can be usefully decomposed into a dense core plus an outlying, loosely-connected periphery. Here we propose an algorithm for performing such a decomposition on empirical network data using methods of statistical inference. Our…

Social and Information Networks · Computer Science 2015-06-22 Xiao Zhang , Travis Martin , M. E. J. Newman

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Neurons and Cognition · Quantitative Biology 2024-05-13 Anastasiya Salova , István A. Kovács
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