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Cells integrate signals and make decisions about their future state in short amounts of time. A lot of theoretical effort has gone into asking how to best design gene regulatory circuits that fulfill a given function, yet little is known…

Molecular Networks · Quantitative Biology 2025-10-08 Tarek Tohme , Massimo Vergassola , Thierry Mora , Aleksandra M. Walczak

In this paper we present a new approach to modeling finite set domain constraint problems using Reduced Ordered Binary Decision Diagrams (ROBDDs). We show that it is possible to construct an efficient set domain propagator which compactly…

Artificial Intelligence · Computer Science 2011-09-13 P. J. Hawkins , V. Lagoon , P. J. Stuckey

Column Generation (CG) is a popular method dedicated to enhancing computational efficiency in large scale Combinatorial Optimization (CO) problems. It reduces the number of decision variables in a problem by solving a pricing problem. For…

Machine Learning · Computer Science 2025-04-18 Abdo Abouelrous , Laurens Bliek , Adriana F. Gabor , Yaoxin Wu , Yingqian Zhang

Parametric models abstract part of the specification of dynamical models by integral parameters. They are for example used in computational systems biology, notably with parametric regulatory networks, which specify the global architecture…

Logic in Computer Science · Computer Science 2018-11-30 Stefan Haar , Juraj Kolčák , Loïc Paulevé

Given a linear system, we consider the problem of finding a small set of variables to affect with an input so that the resulting system is controllable. We show that this problem is NP-hard; indeed, we show that even approximating the…

Optimization and Control · Mathematics 2014-05-06 Alex Olshevsky

Hard constraints in generative sampling are typically enforced by projection, applied either once at the end of sampling or after every update. This binary framing overlooks a fundamental issue: projection changes the distribution of states…

Machine Learning · Computer Science 2026-05-13 Noah Trupin , Yexiang Xue

We study the fixed points of outer-totalistic cellular automata on sparse random regular graphs. These can be seen as constraint satisfaction problems, where each variable must adhere to the same local constraint, which depends solely on…

Disordered Systems and Neural Networks · Physics 2024-12-06 Cédric Koller , Freya Behrens , Lenka Zdeborová

Our model is a generalized linear programming relaxation of a much studied random K-SAT problem. Specifically, a set of linear constraints C on K variables is fixed. From a pool of n variables, K variables are chosen uniformly at random and…

Probability · Mathematics 2007-05-23 David Gamarnik

Matrix Completion is the problem of recovering an unknown real-valued low-rank matrix from a subsample of its entries. Important recent results show that the problem can be solved efficiently under the assumption that the unknown matrix is…

Computational Complexity · Computer Science 2014-04-11 Moritz Hardt , Raghu Meka , Prasad Raghavendra , Benjamin Weitz

One of the challenges in the study of Generative Adversarial Networks (GANs) is the difficulty of its performance control. Lipschitz constraint is essential in guaranteeing training stability for GANs. Although heuristic methods such as…

Computer Vision and Pattern Recognition · Computer Science 2020-12-24 Kanglin Liu , Guoping Qiu

Assessing the validity of a real-world system with respect to given quality criteria is a common yet costly task in industrial applications due to the vast number of required real-world tests. Validating such systems by means of simulation…

Machine Learning · Computer Science 2024-09-06 David Reeb , Kanil Patel , Karim Barsim , Martin Schiegg , Sebastian Gerwinn

It has been shown that the effectiveness of graph convolutional network (GCN) for recommendation is attributed to the spectral graph filtering. Most GCN-based methods consist of a graph filter or followed by a low-rank mapping optimized…

Information Retrieval · Computer Science 2024-06-14 Shaowen Peng , Xin Liu , Kazunari Sugiyama , Tsunenori Mine

We study a typical optimization model where the optimization variable is composed of multiple probability distributions. Though the model appears frequently in practice, such as for policy problems, it lacks specific analysis in the general…

Optimization and Control · Mathematics 2024-10-25 Shihong Ding , Long Yang , Luo Luo , Cong Fang

We study the following generalized matrix rank estimation problem: given an $n \times n$ matrix and a constant $c \geq 0$, estimate the number of eigenvalues that are greater than $c$. In the distributed setting, the matrix of interest is…

Data Structures and Algorithms · Computer Science 2015-02-09 Yuchen Zhang , Martin J. Wainwright , Michael I. Jordan

Distributed matrix computations -- matrix-matrix or matrix-vector multiplications -- are well-recognized to suffer from the problem of stragglers (slow or failed worker nodes). Much of prior work in this area is (i) either sub-optimal in…

Information Theory · Computer Science 2020-06-03 Anindya B. Das , Aditya Ramamoorthy , Namrata Vaswani

General circulation models (GCMs) typically have a grid size of 25--200 km. Parametrizations are used to represent diabatic processes such as radiative transfer and cloud microphysics and account for sub-grid-scale motions and variability.…

Atmospheric and Oceanic Physics · Physics 2019-10-23 Noah D Brenowitz , Christopher S Bretherton

Graph neural networks (GNNs) have gained popularity for various graph-related tasks. However, similar to deep neural networks, GNNs are also vulnerable to adversarial attacks. Empirical studies have shown that adversarially robust…

Machine Learning · Statistics 2024-07-09 Tan Sun , Junhong Lin

In industrial model predictive controllers (MPCs), models generated from regression-based system identification methods typically contain small or even physically non-existent degrees of freedom. Control issues can arise when the…

Systems and Control · Electrical Eng. & Systems 2022-06-10 Daniel L. O'Connor , Lim C. Siang , Shams Elnawawi

We propose a novel approach to design a robust Model Predictive Controller (MPC) for constrained uncertain linear systems. The uncertain system is modeled as linear parameter varying with additive disturbance. Set bounds for the system…

Systems and Control · Electrical Eng. & Systems 2022-08-11 Monimoy Bujarbaruah , Ugo Rosolia , Yvonne R Stürz , Xiaojing Zhang , Francesco Borrelli

In this paper we present a new bound obtained with the probabilistic method for the solution of the Set Covering problem with unit costs. The bound is valid for problems of fixed dimension, thus extending previous similar asymptotic…

Combinatorics · Mathematics 2014-07-18 Giovanni Felici , Sokol Ndreca , Aldo Procacci , Benedetto Scoppola