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Robustness of spatial pattern against perturbations is an indispensable property of developmental processes for organisms, which need to adapt to changing environments. Although specific mechanisms for this robustness have been extensively…

Adaptation and Self-Organizing Systems · Physics 2017-04-05 Tetsuhiro S. Hatakeyama , Kunihiko Kaneko

Can intelligence optimise Digital Ecosystems? How could a distributed intelligence interact with the ecosystem dynamics? Can the software components that are part of genetic selection be intelligent in themselves, as in an adaptive…

Neural and Evolutionary Computing · Computer Science 2009-09-21 G. Briscoe , P. De Wilde

Antimicrobial resistance to drugs (AMR), a global threat to human and animal health, is often regarded as resulting from cooperative behaviour. Moreover, microbes generally evolve in volatile environments that, together with demographic…

Populations and Evolution · Quantitative Biology 2024-06-18 Lluís Hernández-Navarro , Matthew Asker , Mauro Mobilia

With the characterisations of potentially habitable planetary atmospheres on the horizon, the search for biosignatures is set to become a major area of research in the coming decades. To understand the atmospheric characteristics that might…

Earth and Planetary Astrophysics · Physics 2022-08-17 A. E. Nicholson , S. J. Daines , N. J. Mayne , J. K. Eager-Nash , T. M. Lenton , K. Kohary

We develop a quantum information protocol that models the biological behaviors of individuals living in a natural selection scenario. The artificially engineered evolution of the quantum living units shows the fundamental features of life…

Quantum Physics · Physics 2016-02-16 U. Alvarez-Rodriguez , M. Sanz , L. Lamata , E. Solano

We examine the evolution of expression patterns and the organization of genetic information in populations of self-replicating digital organisms. Seeding the experiments with a linearly expressed ancestor, we witness the development of…

adap-org · Physics 2007-05-23 Charles Ofria , Christoph Adami

Cells sense environmental signals and transmit information intracellularly through changes in the abundance of molecular components. Such molecular abundances can be measured in single cells and exhibit significant heterogeneity in clonal…

Quantitative Methods · Quantitative Biology 2024-09-27 Raymond Fan , Andreas Hilfinger

The search for biosignatures necessitates developing our understanding of life under different conditions. If life can influence the climate evolution of its planet then understanding the behaviour of life-climate feedbacks under extreme…

Earth and Planetary Astrophysics · Physics 2023-04-05 A. E. Nicholson , N. J. Mayne

A primary motivation for our research in Digital Ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…

Neural and Evolutionary Computing · Computer Science 2009-10-05 Gerard Briscoe , Philippe De Wilde

Complex evolving systems such as the biosphere, ecosystems and societies exhibit sudden collapses, for reasons that are only partially understood. Here we study this phenomenon using a mathematical model of a system that evolves under…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Ravi Mehrotra , Vikram Soni , Sanjay Jain

Previous studies have inferred robust stability of reaction networks by utilizing linear programs or iterative algorithms. Such algorithms become tedious or computationally infeasible for large networks. In addition, they operate like…

Optimization and Control · Mathematics 2023-02-13 M. Ali Al-Radhawi

The discovery of inhabited exoplanets hinges on identifying biosignature gases. JWST can reveal biosignature gases, though current discoveries have yet to evidence life. The central challenge is attribution: how can we confidently identify…

Earth and Planetary Astrophysics · Physics 2026-02-17 Tereza Constantinou , Oliver Shorttle , Miles Cranmer , Paul B. Rimmer

The persistence of life requires populations to adapt at a rate commensurate with the dynamics of their environment. Successful populations that inhabit highly variable environments have evolved mechanisms to increase the likelihood of…

Genomics · Quantitative Biology 2007-05-23 Taison Tan , Leonard D. Bogarad , Michael W. Deem

A dynamical systems scenario for developmental cell biology is proposed, based on numerical studies of a system with interacting units with internal dynamics and reproduction. Diversification, formation of discrete and recursive types, and…

chao-dyn · Physics 2009-10-31 Kunihiko Kaneko , Chikara Furusawa

We study the probabilities of evolution based on random mutations and natural selection. We conclude that evolution to multicellular eukaryots, or even prokaryots, is unlikely to be the result of only random mutations. Complex organisms…

Populations and Evolution · Quantitative Biology 2007-05-23 B. Hoeneisen , G. Trueba

We study a genetic regulatory network model developed to demonstrate that genetic robustness can evolve through stabilizing selection for optimal phenotypes. We report preliminary results on whether such selection could result in a…

Molecular Networks · Quantitative Biology 2010-12-07 Volkan Sevim , Per Arne Rikvold

Behavioral changes in animals and humans, as a consequence of an error or a verbal instruction, can be extremely rapid. Improvement in behavioral performances are usually associated in machine learning and reinforcement learning to synaptic…

Neurons and Cognition · Quantitative Biology 2025-03-12 Cristiano Capone , Luca Falorsi

This short paper presents an abstract, tunable model of genomic structural change within the cell lifecycle and explores its use with simulated evolution. A well-known Boolean model of genetic regulatory networks is extended to include…

Computational Engineering, Finance, and Science · Computer Science 2012-01-18 Larry Bull

A primary motivation for our research in digital ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-01-31 Gerard Briscoe , Philippe De Wilde

In order to make a case for or against a trend in the evolution of complexity in biological evolution, complexity needs to be both rigorously defined and measurable. A recent information-theoretic (but intuitively evident) definition…

Biological Physics · Physics 2016-09-08 Christoph Adami , Charles Ofria , Travis C. Collier