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Virus trafficking is fundamental for infection success and plasmid cytosolic trafficking is a key step of gene delivery. Based on the main physical properties of the cellular transport machinery such as microtubules, motor proteins, our…

Quantitative Methods · Quantitative Biology 2007-12-21 Thibault Lagache , David Holcman

We consider a generational and continuous-time two-phase model of the cell cycle. The first model is given by a stochastic operator, and the second by a piecewise deterministic Markov process. In the second case we also introduce a…

Probability · Mathematics 2018-07-30 Katarzyna Pichór , Ryszard Rudnicki

This article examines how diseases on random networks spread in time. The disease is described by a probability distribution function for the number of infected and recovered individuals, and the probability distribution is described by a…

Adaptation and Self-Organizing Systems · Physics 2013-05-29 M. Marder

In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close relation with the branching process advanced by Demetrius,…

Populations and Evolution · Quantitative Biology 2014-02-11 Fernando Antoneli , Francisco Bosco , Diogo Castro , Luiz Mario Janini

We study a stochastic epidemic model consisting of elements (organisms in a community or cells in tissue) with fixed positions, in which damage or disease is transmitted by diffusing agents ("signals") emitted by infected individuals. The…

Populations and Evolution · Quantitative Biology 2015-06-05 Fernando P. Faria , Ronald Dickman

The recent interest in human dynamics has led researchers to investigate the stochastic processes that explain human behaviour in different contexts. Here we propose a generative model to capture the essential dynamics of survival analysis,…

Physics and Society · Physics 2015-06-18 Trevor Fenner , Mark Levene , George Loizou

The paper deals with the setting where two viruses (say virus 1 and virus 2) coexist in a population, and they are not necessarily mutually exclusive, in the sense that infection due to one virus does not preclude the possibility of…

Populations and Evolution · Quantitative Biology 2024-07-12 Sebin Gracy , Philip E. Paré , Ji Liu , Henrik Sandberg , Carolyn L. Beck , Karl Henrik Johansson , Tamer Başar

In proliferating cell populations, adaptive changes to biochemical reactions can change a cell's division time, which in turn can change the population size. However, biochemical reactions are subject to noise, and therefore the conditions…

Biological Physics · Physics 2026-05-06 Krishna P. Ramachandran , Motasem ElGamel , Farshid Jafarpour , Andrew Mugler

It is the main purpose of this paper to introduce a graph-valued stochastic process in order to model the spread of a communicable infectious disease. The major novelty of the SIR model we promote lies in the fact that the social network on…

Applications · Statistics 2014-02-06 Charanpal Dhanjal , Stéphan Clémençon

The importation and subsequent establishment of novel pathogenic strains in a population is subject to a large degree of uncertainty due to the stochastic nature of the disease dynamics. Mathematical models need to take this stochasticity…

Populations and Evolution · Quantitative Biology 2024-12-02 Jacob Curran-Sebastian , Frederik Mølkjær Andersen , Samir Bhatt

In this work, we derive a system of Boltzmann-type equations to describe the spread of SARS-CoV-2 virus at the microscopic scale, that is by modeling the human-to-human mechanisms of transmission. To this end, we consider two populations,…

Populations and Evolution · Quantitative Biology 2024-02-09 Marzia Bisi , Silvia Lorenzani

The field of epidemiology has presented fascinating and relevant questions for mathematicians, primarily concerning the spread of viruses in a community. The importance of this research has greatly increased over time as its applications…

One of the popular dynamics on complex networks is the epidemic spreading. An epidemic model describes how infections spread throughout a network. Among the compartmental models used to describe epidemics, the…

Physics and Society · Physics 2011-07-14 Faryad Darabi Sahneh , Caterina Scoglio

We consider the time evolution of the supercritical Galton-Watson model of branching particles with extra parameter (mass). In the moment of the division the mass of the particle (which is growing linearly after the birth) is divided in…

Probability · Mathematics 2018-08-20 Gregory Derfel , Yaqin Feng , Stanislav Molchanov

Lymphocyte populations, stimulated in vitro or in vivo, grow as cells divide. Stochastic models are appropriate because some cells undergo multiple rounds of division, some die, and others of the same type in the same conditions do not…

Cell Behavior · Quantitative Biology 2021-12-02 Giulia Belluccini , Martín López-García , Grant Lythe , Carmen Molina-París

A novel bioinspired metaheuristic is proposed in this work, simulating how the coronavirus spreads and infects healthy people. From an initial individual (the patient zero), the coronavirus infects new patients at known rates, creating new…

Despite being similar in structure, functioning, and size viral pathogens enjoy very different mostly well-defined ways of life. They occupy their hosts for a few days (influenza), for a few weeks (measles), or even lifelong (HCV), which…

Populations and Evolution · Quantitative Biology 2020-05-01 Alexander Lange

We consider a simple stochastic model for the spread of a disease caused by two virus strains in a closed homogeneously mixing population of size N. The spread of each strain in the absence of the other one is described by the stochastic…

Probability · Mathematics 2018-02-13 Fabio Lopes , Malwina Luczak

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

Applications · Statistics 2018-01-30 Tom Britton

The design of protocols to suppress the propagation of viral infections is an enduring enterprise, especially hindered by limited knowledge of the mechanisms through which extinction of infection propagation comes about. We here report on a…

Populations and Evolution · Quantitative Biology 2015-02-18 Jose A. Cuesta , Jacobo Aguirre , Jose A. Capitan , Susanna C. Manrubia
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