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Microarray technology is a process that allows thousands of genes simultaneously monitor to various experimental conditions. It is used to identify the co-expressed genes in specific cells or tissues that are actively used to make proteins,…

Computational Engineering, Finance, and Science · Computer Science 2013-07-16 T. Chandrasekhar , K. Thangavel , E. Elayaraja

Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. Identification of co-expressed genes and coherent patterns is the central goal in microarray or…

Computational Engineering, Finance, and Science · Computer Science 2012-01-25 T. Chandrasekhar , K. Thangavel , E. Elayaraja

Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. Identification of co-expressed genes and coherent patterns is the central goal in microarray or…

Computational Engineering, Finance, and Science · Computer Science 2013-07-15 T. Chandrasekhar , K. Thangavel , E. Elayaraja , E. N. Sathishkumar

Clustering is a popular data mining technique that aims to partition an input space into multiple homogeneous regions. There exist several clustering algorithms in the literature. The performance of a clustering algorithm depends on its…

Human-Computer Interaction · Computer Science 2020-08-20 Sudip Poddar , Anirban Mukhopadhyay

Microarray data analysis is one of the major area of research in the field computational biology. Numerous techniques like clustering, biclustering are often applied to microarray data to extract meaningful outcomes which play key roles in…

Neural and Evolutionary Computing · Computer Science 2019-09-04 Shubhankar Mohapatra , Moumita Sarkar , Anjali Mohapatra , Bhawani Sankar Biswal

Microarray is a technology to quantitatively monitor the expression of large number of genes in parallel. It has become one of the main tools for global gene expression analysis in molecular biology research in recent years. The large…

Quantitative Methods · Quantitative Biology 2015-06-18 Min Xu

The expression levels of many thousands of genes can be measured simultaneously by DNA microarrays (chips). This novel experimental tool has revolutionized research in molecular biology and generated considerable excitement. A typical…

Biological Physics · Physics 2007-05-23 Eytan Domany

To understand complex biological systems, the research community has produced huge corpus of gene expression data. A large number of clustering approaches have been proposed for the analysis of gene expression data. However, extracting…

Computational Engineering, Finance, and Science · Computer Science 2010-03-28 Swathi. H

Gene expression data is often collected in time series experiments, under different experimental conditions. There may be genes that have very different gene expression profiles over time, but that adjust their gene expression patterns in…

Methodology · Statistics 2021-12-02 Susana Conde , Shahin Tavakoli , Daphne Ezer

In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics. One key problem is to identify aberrant patterns of these processes and…

Applications · Statistics 2012-10-03 Matthias Kormaksson , James G. Booth , Maria E. Figueroa , Ari Melnick

Microarray is one of the essential technologies used by the biologist to measure genome-wide expression levels of genes in a particular organism under some particular conditions or stimuli. As microarrays technologies have become more…

Artificial Intelligence · Computer Science 2020-05-05 Khalid Raza

Computational analysis methods including machine learning have a significant impact in the fields of genomics and medicine. High-throughput gene expression analysis methods such as microarray technology and RNA sequencing produce enormous…

Genomics · Quantitative Biology 2022-09-28 Nikita Bhandari , Rahee Walambe , Ketan Kotecha , Satyajeet Khare

We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

Biological Physics · Physics 2009-11-06 G. Getz , E. Levine , E. Domany

Traditional clustering methods are limited when dealing with huge and heterogeneous groups of gene expression data, which motivates the development of bi-clustering methods. Bi-clustering methods are used to mine bi-clusters whose subsets…

Computer Vision and Pattern Recognition · Computer Science 2020-05-13 Kaijie Xu , Witold Pedrycz , Zhiwu Li , Yinghui Quan , Weike Nie

Microarray technology is known as one of the most important tools for collecting DNA expression data. This technology allows researchers to investigate and examine types of diseases and their origins. However, microarray data are often…

Quantitative Methods · Quantitative Biology 2021-01-05 Babak Nouri-Moghaddam , Mehdi Ghazanfari , Mohammad Fathian

This report explores the application of machine learning techniques on short timeseries gene expression data. Although standard machine learning algorithms work well on longer time-series', they often fail to find meaningful insights from…

Genomics · Quantitative Biology 2021-11-17 Akankshita Dash

Clustering of gene expression time series gives insight into which genes may be coregulated, allowing us to discern the activity of pathways in a given microarray experiment. Of particular interest is how a given group of genes varies with…

Quantitative Methods · Quantitative Biology 2018-02-13 Muhammad Arifur Rahman , Paul R. Heath , Neil D. Lawrence

Clustering is a commonly used method for exploring and analysing data where the primary objective is to categorise observations into similar clusters. In recent decades, several algorithms and methods have been developed for analysing…

Machine Learning · Computer Science 2021-02-17 Bryar A. Hassan , Tarik A. Rashid

Motivation: Clustering techniques are routinely applied to identify patterns of co-expression in gene expression data. Co-regulation, and involvement of genes in similar cellular function, is subsequently inferred from the clusters which…

Quantitative Methods · Quantitative Biology 2016-06-10 Patrick E. McSharry , Edmund J. Crampin

A widely used approach for extracting information from gene expression data employ the construction of a gene co-expression network and the subsequent application of algorithms that discover network structure. In particular, a common goal…

Genomics · Quantitative Biology 2024-08-20 Niloofar Aghaieabiane , Ioannis Koutis
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