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Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou

The chromatin folding and the spatial arrangement of chromosomes in the cell play a crucial role in DNA replication and genes expression. An improper chromatin folding could lead to malfunctions and, over time, diseases. For eukaryotes,…

Machine Learning · Statistics 2025-11-13 Eloïse Touron , Pedro L. C. Rodrigues , Julyan Arbel , Nelle Varoquaux , Michael Arbel

Interactive segmentation entails a human marking an image to guide how a model either creates or edits a segmentation. Our work addresses limitations of existing methods: they either only support one gesture type for marking an image (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Josh Myers-Dean , Yifei Fan , Brian Price , Wilson Chan , Danna Gurari

Understanding the three-dimensional (3D) structure of the genome is essential for elucidating vital biological processes and their links to human disease. To determine how the genome folds within the nucleus, chromosome conformation capture…

Image segmentation plays a crucial role in extracting objects of interest and identifying their boundaries within an image. However, accurate segmentation becomes challenging when dealing with occlusions, obscurities, or noise in corrupted…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Daoping Zhang , Xue-Cheng Tai , Lok Ming Lui

Thalamic alterations are relevant to many neurological disorders including Alzheimer's disease, Parkinson's disease and multiple sclerosis. Routine interventions to improve symptom severity in movement disorders, for example, often consist…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Veronica Corona , Jan Lellmann , Peter Nestor , Carola-Bibiane Schoenlieb , Julio Acosta-Cabronero

In this contribution, a semi-automatic segmentation algorithm for (medical) image analysis is presented. More precise, the approach belongs to the category of interactive contouring algorithms, which provide real-time feedback of the…

Computer Vision and Pattern Recognition · Computer Science 2014-06-10 Jan Egger

Image segmentation is the problem of partitioning an image into different subsets, where each subset may have a different characterization in terms of color, intensity, texture, and/or other features. Segmentation is a fundamental component…

Computer Vision and Pattern Recognition · Computer Science 2015-11-03 M. Abdelsamea

We present an automatic method to identify galaxy mergers using the morphological information contained in the residual images of galaxies after the subtraction of a Sersic model. The removal of the bulk signal from the host galaxy light is…

In the paper a piecewise constant image approximations of sequential number of pixel clusters or segments are treated. A majorizing of optimal approximation sequence by hierarchical sequence of image approximations is studied. Transition…

Computer Vision and Pattern Recognition · Computer Science 2014-06-03 M. Kharinov

Cardiac magnetic resonance imaging (MRI) is a pivotal tool for assessing cardiac function. Precise segmentation of cardiac structures is imperative for accurate cardiac functional evaluation. This paper introduces a semi-supervised model…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Hejun Huang , Zuguo Chen , Yi Huang , Guangqiang Luo , Chaoyang Chen , Youzhi Song

We investigate a densely packed, non-random arrangement of forty-six chromosomes (46,XY) in human nuclei. Here, we model systems-level chromosomal crosstalk by unifying intrinsic parameters (chromosomal length and number of genes) across…

Genomics · Quantitative Biology 2017-11-09 Sarosh N. Fatakia , Ishita S. Mehta , Basuthkar J. Rao

We introduce a method for automated temporal segmentation of human motion data into distinct actions and compositing motion primitives based on self-similar structures in the motion sequence. We use neighbourhood graphs for the partitioning…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Björn Krüger , Anna Vögele , Tobias Willig , Angela Yao , Reinhard Klein , Andreas Weber

Array-Based Comparative Genomic Hybridization (aCGH) is a method used to search for genomic regions with copy numbers variations. For a given aCGH profile, one challenge is to accurately segment it into regions of constant copy number.…

Quantitative Methods · Quantitative Biology 2009-10-08 Kevin Bleakley , Jean-Philippe Vert

Multiple myeloma cancer is a type of blood cancer that happens when the growth of abnormal plasma cells becomes out of control in the bone marrow. There are various ways to diagnose multiple myeloma in bone marrow such as complete blood…

Image and Video Processing · Electrical Eng. & Systems 2021-05-14 Afshin Bozorgpour , Reza Azad , Eman Showkatian , Alaa Sulaiman

Several modern genomic technologies, such as DNA-Methylation arrays, measure spatially registered probes that number in the hundreds of thousands across multiplechromosomes. The measured probes are by themselves less interesting…

Applications · Statistics 2016-11-16 John Nagorski , Genevera I. Allen

Quantifying the accuracy of segmentation and manual delineation of organs, tissue types and tumors in medical images is a necessary measurement that suffers from multiple problems. One major shortcoming of all accuracy measures is that they…

Computer Vision and Pattern Recognition · Computer Science 2016-04-19 Hamid R. Tizhoosh , Ahmed A. Othman

Nuclear segmentation is important and frequently demanded for pathology image analysis, yet is also challenging due to nuclear crowdedness and possible occlusion. In this paper, we present a novel bottom-up method for nuclear segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Jiahui Li , Zhiqiang Hu , Shuang Yang

Segmentation is crucial for brain gliomas as it delineates the glioma s extent and location, aiding in precise treatment planning and monitoring, thus improving patient outcomes. Accurate segmentation ensures proper identification of the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Kiranmayee Janardhan , Vinay Martin DSa Prabhu , T. Christy Bobby

Medical image segmentation has become an essential technique in clinical and research-oriented applications. Because manual segmentation methods are tedious, and fully automatic segmentation lacks the flexibility of human intervention or…

Image and Video Processing · Electrical Eng. & Systems 2019-04-24 Kevin Karsch , Qing He , Ye Duan