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Motivated by recent experiments on growing fibroblasts, we examine the development of nematic order in a colony of elongated cells proliferating on a nematic elastomer substrate. After sparse seeding, the cells divide and grow into locally…

Soft Condensed Matter · Physics 2026-01-06 Toshi Parmar , Fridtjof Brauns , Yimin Luo , M. Cristina Marchetti

Several recent experiments, including our own in the fission yeast, S. pombe, have characterized the motions of gene loci within living nuclei by measuring the locus position over time, then proceeding to obtain the statistical properties…

Biological Physics · Physics 2021-03-17 Mary Lou P Bailey , Hao Yan , Ivan Surovtsev , Jessica F Williams , Megan C King , Simon G J Mochrie

Isotopologue abundance ratios are important to understand the evolution of astrophysical objects and ultimately the origins of a planetary system like our own. Being nitrogen a fundamental ingredient of pre-biotic material, understanding…

Astrophysics of Galaxies · Physics 2022-08-10 Silvia Spezzano , Paola Caselli , Olli Sipilä , Luca Bizzocchi

Polarons play a major role in the description of optical, electrical and dielectrical properties of several ferroelectric oxides. The motion of those particles occur by elementary hops among the material lattice sites. In order to compute…

Materials Science · Physics 2024-10-17 Anton Pfannstiel , Mirco imlau , Marco Bazzan , Laura Vittadello

A ubiquitous observation in cell biology is that diffusion of macromolecules and organelles is anomalous, and a description simply based on the conventional diffusion equation with diffusion constants measured in dilute solution fails. This…

Soft Condensed Matter · Physics 2013-03-14 Felix Höfling , Thomas Franosch

Multi-nucleated cells exist in all domains of life, ranging from animals, plants and fungi to single-celled organisms such as the slime mold Physarum polycephalum. The large cell size, in the case of Physarum reaching centimeters and more,…

Biological Physics · Physics 2026-05-12 Johnny Tong , Kaspar Wachinger , Fabian K. Henn , Nico Schramma , Siyu Chen , Karen Alim

Transport of solid particles in blood flow exhibits qualitative differences in the transport mechanism when the particle varies from nanoscale to microscale size comparable to the red blood cell (RBC). The effect of microscale particle…

Soft Condensed Matter · Physics 2019-10-15 Zixiang Liu , Jonathan R. Clausen , Rekha R. Rao , Cyrus K. Aidun

A recent experiment [Sadoon AA, Wang Y. 2018 Phys. Rev. E 98, 042411] has revealed that nucleoid associated proteins (i.e., DNA-binding proteins) exhibit highly heterogeneous diffusion processes in bacteria where not only the diffusion…

Statistical Mechanics · Physics 2021-03-09 Yuichi Itto , Christian Beck

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

Populations and Evolution · Quantitative Biology 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

We study translational and rotational diffusion of anisotropic gold nanoparticles (NPs) dispersed in the bulk of a nematic liquid crystal fluid host. Experimental data reveal strong anisotropy of translational diffusion with respect to the…

Soft Condensed Matter · Physics 2016-12-23 Bohdan Senyuk , David Glugla , Ivan I. Smalyukh

New insights into transport properties of nanostructures with a linear dispersion along one direction and a quadratic dispersion along another are obtained by analysing their spectral stability properties under small perturbations.…

Mathematical Physics · Physics 2022-08-22 David Krejcirik , Pedro. R. S. Antunes

Recent studies have suggested that the Nuclear Pore Complex (NPC) plays a significant role in mechanotransduction. When a force is exerted, the NPC's diameter widens, leading to an increased molecular flux into the nucleus. In this study,…

Biological Physics · Physics 2025-04-09 Atsushi Matsuda , Mohammad R. K. Mofrad

Single-molecule FRET is widely used to study helicases by detecting distance changes between a fluorescent donor and an acceptor anchored to overhangs of a forked DNA duplex. However, it has lacked single-base pair (1-bp) resolution…

Biological Physics · Physics 2017-10-04 Wenxia Lin , Jianbing Ma , Daguan Nong , Chunhua Xu , Bo Zhang , Jinghua Li , Qi Jia , Shuoxing Dou , Xuguang Xi , Ying Lu , Ming Li

Calculations of the conductance of a carbon nanotube (CNT)-molecule-CNT structure are in agreement with experimental measurements [1]. The features in the transmission correspond directly to the features of the isolated molecular orbitals.…

Other Condensed Matter · Physics 2015-05-13 Nicolas A. Bruque , M. K. Ashraf , Roger K. Lake

Thermoresponsive hydrogels have been studied intensively for creating smart drug carriers and controlled drug delivery. Understanding the drug release kinetics and corresponding transport mechanisms of nanoparticles (NPs) in a…

Soft Condensed Matter · Physics 2020-05-12 Yi Wang , Zhen Li , Jie Ouyang , George Em Karniadakis

Cell polarization underlies many cellular processes, such as differentiation, migration, and budding. Many living cells, such as budding yeast and fission yeast, use cytoskeletal structures to actively transport proteins to one location on…

Biological Physics · Physics 2022-06-22 Harmen Wierenga , Pieter Rein ten Wolde

Nitrogen-bearing molecules display variable isotopic fractionation levels in different astronomical environments such as in the interstellar medium or in the Solar System. Models of interstellar chemistry are unable to induce nitrogen…

Astrophysics of Galaxies · Physics 2020-12-15 Jean-Christophe Loison , Valentine Wakelam , Pierre Gratier , Kevin M. Hickson

The proper positioning of the mitotic spindle is crucial for asymmetric cell division and generating cell diversity during development. Proper position in the single-cell embryo of Caenorhabditis elegans is achieved initially by the…

Biological Physics · Physics 2015-11-10 Ehssan Nazockdast , Abtin Rahimian , Daniel Needleman , Michael Shelley

GaSb/InAs/GaSb layer stacks have been grown on InAs metamorphic substrates (pseudosubstrates) by MOVPE, using nitrogen as major carrier gas. We demonstrate that GaSb growth by nitrogen MOVPE on InAs metamorphic substrates (and on InAs…

The more we learn about the cytoplasm of cells, the more we realise that the cytoplasm is not uniform but instead is highly inhomogeneous. In any inhomogeneous solution, there are concentration gradients, and particles move either up or…

Subcellular Processes · Quantitative Biology 2019-04-03 Richard P. Sear
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