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Many complex networks, ranging from social to biological systems, exhibit structural patterns consistent with an underlying hyperbolic geometry. Revealing the dimensionality of this latent space can disentangle the structural complexity of…

Topological data analysis (TDA) is a branch of computational mathematics, bridging algebraic topology and data science, that provides compact, noise-robust representations of complex structures. Deep neural networks (DNNs) learn millions of…

A primary hypothesis that drives scientific and engineering studies is that data has structure. The dominant paradigms for describing such structure are statistics (e.g., moments, correlation functions) and signal processing (e.g.,…

Algebraic Topology · Mathematics 2020-11-11 Alexander D. Smith , Pawel Dlotko , Victor M. Zavala

Using dimensionally reduced models for the numerical simulation of thin objects is highly attractive as this reduces the computational work substantially. The case of narrow thin elastic bands is considered and a convergent finite element…

Numerical Analysis · Mathematics 2019-11-20 Sören Bartels

Topological data analysis (TDA) provides a growing body of tools for computing geometric and topological information about spaces from a finite sample of points. We present a new adaptive algorithm for finding provably dense samples of…

Algebraic Topology · Mathematics 2018-10-22 Emilie Dufresne , Parker B. Edwards , Heather A. Harrington , Jonathan D. Hauenstein

In this work, we present a computational framework for exploring and analyzing the macroscopic dynamics of complex agent-based network models by integrating Topological Data Analysis with the Equation-Free Method. To demonstrate the…

Dynamical Systems · Mathematics 2026-02-17 Konstantinos Spiliotis , Ole Sönnerborn , Haralampos Hatzikirou , Nikos I. Kavallaris

Advances in imaging techniques enable high resolution 3D visualisation of vascular networks over time and reveal abnormal structural features such as twists and loops, and their quantification is an active area of research. Here we showcase…

Topological entropy measures the number of distinguishable orbits in a dynamical system, thereby quantifying the complexity of chaotic dynamics. One approach to computing topological entropy in a two-dimensional space is to analyze the…

Computational Physics · Physics 2019-04-19 Eric Roberts , Suzanne Sindi , Spencer Smith , Kevin Mitchell

We present a new method for exploring cancer gene expression data based on tools from algebraic topology. Our method selects a small relevant subset from tens of thousands of genes while simultaneously identifying nontrivial higher order…

Genomics · Quantitative Biology 2014-10-15 Svetlana Lockwood , Bala Krishnamoorthy

We present a methodology to simulate the mechanics of knots in elastic rods using geometrically nonlinear, full three-dimensional (3D) finite element analysis. We focus on the mechanical behavior of knots in tight configurations, for which…

Soft Condensed Matter · Physics 2021-02-03 Changyeob Baek , Paul Johanns , Tomohiko G. Sano , Paul Grandgeorge , Pedro M. Reis

This paper presents a method for time-lapse 3D cell analysis. Specifically, we consider the problem of accurately localizing and quantitatively analyzing sub-cellular features, and for tracking individual cells from time-lapse 3D confocal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Jiaxiang Jiang , Amil Khan , S. Shailja , Samuel A. Belteton , Michael Goebel , Daniel B. Szymanski , B. S. Manjunath

With the rapid adoption of machine learning techniques for large-scale applications in science and engineering comes the convergence of two grand challenges in visualization. First, the utilization of black box models (e.g., deep neural…

Soft gels, formed via the self-assembly of particulate organic materials, exhibit intricate multi-scale structures that provides them with flexibility and resilience when subjected to external stresses. This work combines molecular…

Soft Condensed Matter · Physics 2024-04-05 Alexander Smith , Gavin J. Donley , Emanuela Del Gado , Victor M. Zavala

Characterization of transient intermediate or transition states is crucial for the description of biomolecular folding pathways, which is however difficult in both experiments and computer simulations. Such transient states are typically of…

Biomolecules · Quantitative Biology 2009-11-13 Yuan Yao , Jian Sun , Xuhui Huang , Gregory R. Bowman , Gurjeet Singh , Michael Lesnick

High-dimensional data must be highly structured to be learnable. Although the compositional and hierarchical nature of data is often put forward to explain learnability, quantitative measurements establishing these properties are scarce.…

Machine Learning · Statistics 2025-03-04 Antonio Sclocchi , Alessandro Favero , Noam Itzhak Levi , Matthieu Wyart

Topological data analysis is an emerging area in exploratory data analysis and data mining. Its main tool, persistent homology, has become a popular technique to study the structure of complex, high-dimensional data. In this paper, we…

Graphics · Computer Science 2017-10-04 Mustafa Hajij , Bei Wang , Carlos Scheidegger , Paul Rosen

Social and biological contagions are influenced by the spatial embeddedness of networks. Historically, many epidemics spread as a wave across part of the Earth's surface; however, in modern contagions long-range edges -- for example, due to…

Adaptation and Self-Organizing Systems · Physics 2015-07-31 Dane Taylor , Florian Klimm , Heather A. Harrington , Miroslav Kramar , Konstantin Mischaikow , Mason A. Porter , Peter J. Mucha

Elastic topological states have been receiving increased intention in numerous scientific and engineering fields due to their defect-immune nature, resulting in applications of vibration control and information processing. Here, we present…

Applied Physics · Physics 2023-05-31 Shuaifeng Li , Panayotis G. Kevrekidis , Jinkyu Yang

Identifying the qualitative changes in time-series data provides insights into the dynamics associated with such data. Such qualitative changes can be detected through topological approaches, which first embed the data into a…

Data Analysis, Statistics and Probability · Physics 2019-03-27 Quoc Hoan Tran , Yoshihiko Hasegawa

The investigation of dynamical processes on networks has been one focus for the study of contagion processes. It has been demonstrated that contagions can be used to obtain information about the embedding of nodes in a Euclidean space.…

Algebraic Topology · Mathematics 2022-07-20 Florian Klimm