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Mammalian brains span about 4 orders of magnitude in cortical volume and have to operate in different environments that require diverse behavioral skills. Despite these geometric and behavioral diversities, the examination of cerebral…

Neurons and Cognition · Quantitative Biology 2014-05-19 Jan Karbowski

Surface constructs in snakes reflect desirable design traits for technical surface engineering. Their micro-textural patterns, however, do not lend themselves easily to unified analysis due to species-specific variations in surface geometry…

Biological Physics · Physics 2015-01-26 Hisham A. Abdel-Aal , M. El Mansori

Geometrical frustration arised in spin ices leads to fascinating emergent physical properties. Nowadays there is a wide diversity of the artificial structures, mimicking spin ice at the nanoscale and demonstrating some new effects. Most of…

Understanding the structure of a protein complex is crucial indetermining its function. However, retrieving accurate 3D structures from microscopy images is highly challenging, particularly as many imaging modalities are two-dimensional.…

Quantitative Methods · Quantitative Biology 2021-10-18 Benjamin J. Blundell , Christian Sieben , Suliana Manley , Ed Rosten , QueeLim Ch'ng , Susan Cox

Nowadays, most structural integrity concepts rely on simplified isotropic ma-terial data that are used within continuum mechanics modeling approaches. In contrast, modern casting and forming processes yield complex microstruc-tures coming…

Materials Science · Physics 2019-10-01 Ulrich Krupp , Christian Haase , Wenwen Song , Wolfgang Bleck , Katrin Jahns

The model analyzes the muscle fiber as a deformable system for which experimental data are determinated with the help of the laws of Newtonian mechanic. The model predicts the four transient phases for the shortening of a muscle fiber…

Tissues and Organs · Quantitative Biology 2013-11-19 Sylvain Louvet

Objective: We confirm that alteration of a neuron structure can induce abnormalities in signal propagation for nervous systems, as observed in brain damage. Here, we investigate the effects of geometrical changes and damage of a neuron…

Biological Physics · Physics 2020-09-04 Ilaria Cinelli , Michel Destrade , Peter McHugh , Maeve Duffy

In this paper we develop a lattice-based computational model focused on bone resorption by osteoclasts in a single cortical basic multicellular unit (BMU). Our model takes into account the interaction of osteoclasts with the bone matrix,…

Tissues and Organs · Quantitative Biology 2015-03-19 P. R. Buenzli , J. Jeon , P. Pivonka , D. W. Smith , P. T. Cummings

The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a…

Neurons and Cognition · Quantitative Biology 2022-10-05 Anne-Marie Rickmann , Fabian Bongratz , Sebastian Pölsterl , Ignacio Sarasua , Christian Wachinger

In this paper a new technique is presented that extracts the geometry of lumbar vertebral bodies from spiral CT scans. Our new multi-step segmentation approach yields highly accurate and precise measurement of the bone mineral density (BMD)…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Andre Mastmeyer , Klaus Engelke , Willi Kalender

Irregular bone remodeling is associated with a number of bone diseases such as osteoporosis and multiple myeloma. Computational and mathematical modeling can aid in therapy and treatment as well as understanding fundamental biology.…

Quantitative Methods · Quantitative Biology 2023-02-14 Jason M. Graham , Bruce P. Ayati , Prem S. Ramakrishnan , James A. Martin

Structural covariance analysis is a widely used structural MRI analysis method which characterises the co-relations of morphology between brain regions over a group of subjects. To our knowledge, little has been investigated in terms of the…

Neurons and Cognition · Quantitative Biology 2020-06-01 Jona Carmon , Jil Heege , Joe H Necus , Thomas W Owen , Gordon Pipa , Marcus Kaiser , Peter N Taylor , Yujiang Wang

The magnetic properties of single-domain nanoparticles with different geometric shapes, crystalline anisotropies and lattice structures are investigated. A recently proposed scaling approach is shown to be universal and in agreement with…

Strongly Correlated Electrons · Physics 2009-11-13 Wen Zhang , Rohit Singh , Noah Bray-Ali , Stephan Haas

Numerically predicting the performance of heterogenous structures without scale separation represents a significant challenge to meet the critical requirements on computational scalability and efficiency -- adopting a mesh fine enough to…

Numerical Analysis · Mathematics 2022-02-23 Ming Li , Jingqiao Hu

A universal framework for modeling composites and fabrics of micro- and nanofibers, such as carbon nanotubes, carbon fibers and amyloid fibrils, is presented. Within this framework, fibers are represented with chains of rigid bodies, linked…

Computational Physics · Physics 2019-03-06 Igor A. Ostanin

Segmentation of distinct bones plays a crucial role in diagnosis, planning, navigation, and the assessment of bone metastasis. It supplies semantic knowledge to visualisation tools for the planning of surgical interventions and the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-15 Eva Schnider , Antal Horváth , Georg Rauter , Azhar Zam , Magdalena Müller-Gerbl , Philippe C. Cattin

Multi-scale 3D characterization is widely used by materials scientists to further their understanding of the relationships between microscopic structure and macroscopic function. Scientific computed tomography (CT) instruments are one of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 S. V. Venkatakrishnan , K. Aditya Mohan , Amir Koushyar Ziabari , Charles A. Bouman

Tendon-bone enthesis connects tendon and bone, two mechanically dissimilar materials, while effectively minimizing stress concentrations, a capability rarely achieved in engineering materials. Its hierarchical organization and graded…

Soft Condensed Matter · Physics 2026-04-14 Zhangke Yang , Zhaoxu Meng

We present an efficient method of imaging 3D nanoscale lattice behavior and strain fields in crystalline materials with a new methodology -- three dimensional Bragg projection ptychography (3DBPP). In this method, the 2D sample structure…

Materials Science · Physics 2017-03-08 S. O. Hruszkewycz , M. Allain , M. V. Holt , C. E. Murray , J. R. Holt , P. H. Fuoss , V. Chamard

Three-dimensional magnetic nanostructures are an emerging platform capable of creating complex topological magnetic fields. The control of localized nanoscale magnetic fields is seen to be of importance for diverse areas from…

Mesoscale and Nanoscale Physics · Physics 2024-10-31 John Fullerton , Charudatta Phatak
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