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Generating molecules, both in a directed and undirected fashion, is a huge part of the drug discovery pipeline. Genetic algorithms (GAs) generate molecules by randomly modifying known molecules. In this paper we show that GAs are very…

Neural and Evolutionary Computing · Computer Science 2023-10-16 Austin Tripp , José Miguel Hernández-Lobato

This work investigates the performance of a Hybrid Quantum Genetic Algorithm (HQGA) compared to a classical Genetic Algorithm (GA) for solving the portfolio optimization problem. Our results indicate that the HQGA converges faster to the…

The genetic algorithm is an optimization procedure motivated by biological evolution and is successfully applied to optimization problems in different areas. A statistical mechanics model for its dynamics is proposed based on the…

Statistical Mechanics · Physics 2009-10-31 Stefan Bornholdt

Proteomics is the large-scale analysis of the proteins. The common method for identifying proteins and characterising their amino acid sequences is to digest the proteins into peptides, analyse the peptides using mass spectrometry and…

Computational Engineering, Finance, and Science · Computer Science 2019-02-05 Samaneh Azari , Bing Xue , Mengjie Zhang , Lifeng Peng

In this article we provide a comprehensive review of the different evolutionary algorithm techniques used to address multimodal optimization problems, classifying them according to the nature of their approach. On the one hand there are…

Neural and Evolutionary Computing · Computer Science 2015-08-24 Noe Casas

Genetic algorithms (GAs) are an optimization technique that has been successfully used on many real-world problems. There exist different approaches to their theoretical study. In this paper we complete a recently presented approach to…

Neural and Evolutionary Computing · Computer Science 2017-07-04 Mauro Castelli , Gianpiero Cattaneo , Luca Manzoni , Leonardo Vanneschi

GoTools is a program which solves life & death problems in the game of Go. This paper describes experiments using a Genetic Algorithm to optimize heuristic weights used by GoTools' tree-search. The complete set of heuristic weights is…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Matthew Pratola , Thomas Wolf

This paper provides an in-depth empirical analysis of several evolutionary algorithms on the one-dimensional spin glass model with power-law interactions. The considered spin glass model provides a mechanism for tuning the effective range…

Disordered Systems and Neural Networks · Physics 2009-07-29 Martin Pelikan , Helmut G. Katzgraber

Many optimization problems in engineering and industrial design applications can be formulated as optimization problems with highly nonlinear objectives, subject to multiple complex constraints. Solving such optimization problems requires…

Neural and Evolutionary Computing · Computer Science 2024-07-03 Xin-She Yang

This study analyzes performance of several genetic and evolutionary algorithms on randomly generated NK fitness landscapes with various values of n and k. A large number of NK problem instances are first generated for each n and k, and the…

Neural and Evolutionary Computing · Computer Science 2008-07-30 Martin Pelikan

Genetic algorithms are a class of heuristic search techniques that apply basic evolutionary operators in a computational setting. We have designed a fully parallel and distributed hardware/software implementation of the generalized…

Astrophysics · Physics 2009-11-07 T. S. Metcalfe , P. Charbonneau

The applications of artificial neural networks in the cosmological field have shone successfully during the past decade, this is due to their great ability of modeling large amounts of datasets and complex nonlinear functions. However, in…

Instrumentation and Methods for Astrophysics · Physics 2024-05-08 Isidro Gómez-Vargas , Joshua Briones Andrade , J. Alberto Vázquez

This paper presents a competent selectomutative genetic algorithm (GA), that adapts linkage and solves hard problems quickly, reliably, and accurately. A probabilistic model building process is used to automatically identify key building…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Kumara Sastry , David E. Goldberg

Here a genetic algorithm (GA) is presented that creates a teaching schedule for a university physics department by algorithmically assigning ${\sim}200$ classes to ${\sim}50$ professors for each of three academic terms per year. The…

Neural and Evolutionary Computing · Computer Science 2025-09-10 Tom Bensky , Karl Saunders

Vision-language retrieval-augmented generation (RAG) has become an effective approach for tackling Knowledge-Based Visual Question Answering (KB-VQA), which requires external knowledge beyond the visual content presented in images. The…

Information Retrieval · Computer Science 2025-09-15 Wei Yang , Jingjing Fu , Rui Wang , Jinyu Wang , Lei Song , Jiang Bian

There is considerable interest in the use of genetic algorithms to solve problems arising in the areas of scheduling and timetabling. However, the classical genetic algorithm paradigm is not well equipped to handle the conflict between…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Kathryn Dowsland

Symbolic-inference methods have recently found a broad application in materials science. In particular, the Sure-Independence Screening and Sparsifying Operator (SISSO) performs symbolic regression and classification by adopting compressed…

Materials Science · Physics 2024-03-26 Aliaksei Mazheika , Sergey V. Levchenko , Luca M. Ghiringhelli

The main problems in modeling interacting galaxies are the extended parameter space and the fairly high CPU costs of self-consistent N-body simulations. Therefore, traditional modeling techniques suffer from either extreme CPU demands or…

Astrophysics · Physics 2007-05-23 Ch. Theis , Ch. Gerds , Ch. Spinneker

This paper presented a genetic algorithm (GA) to solve the container storage problem in the port. This problem is studied with different container types such as regular, open side, open top, tank, empty and refrigerated containers. The…

Neural and Evolutionary Computing · Computer Science 2013-03-06 I. Ayachi , R. Kammarti , M. Ksouri , P. Borne , : , LAGIS , Ecole Centrale de Lille , : , LACS , Ecole Nationale des Ingenieurs de Tunis

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution, which are characterized by successfully finding robust solutions for optimization problems. Here, we propose a subroutine-based quantum genetic…

Quantum Physics · Physics 2024-06-07 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz
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