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Information integration plays a pivotal role in biomedical studies by facilitating the combination and analysis of independent datasets from multiple studies, thereby uncovering valuable insights that might otherwise remain obscured due to…

Methodology · Statistics 2024-07-02 Chixiang Chen , Jia Liang , Elynn Chen , Ming Wang

We consider probabilistic theories in which the most elementary system, a two-dimensional system, contains one bit of information. The bit is assumed to be contained in any complete set of mutually complementary measurements. The…

Quantum Physics · Physics 2009-07-10 Caslav Brukner , Anton Zeilinger

Reliable estimation of predictive uncertainty is crucial for machine learning applications, particularly in high-stakes scenarios where hedging against risks is essential. Despite its significance, there is no universal agreement on how to…

Machine Learning · Computer Science 2025-06-17 Kajetan Schweighofer , Lukas Aichberger , Mykyta Ielanskyi , Sepp Hochreiter

The Information bottleneck method is an unsupervised non-parametric data organization technique. Given a joint distribution P(A,B), this method constructs a new variable T that extracts partitions, or clusters, over the values of A that are…

Machine Learning · Computer Science 2013-01-14 Nir Friedman , Ori Mosenzon , Noam Slonim , Naftali Tishby

Many information sources are considered into data fusion in order to improve the decision in terms of uncertainty and imprecision. For each technique used for data fusion, the asumption on independance is usually made. We propose in this…

Artificial Intelligence · Computer Science 2015-01-23 Mouloud Kharoune , Arnaud Martin

We carry out a systematic study of uncertainty measures that are generic to dynamical processes of varied origins, provided they induce suitable continuous probability distributions. The major technical tool are the information theory…

Statistical Mechanics · Physics 2009-11-13 Piotr Garbaczewski

The integrated information theory of consciousness (IIT) is uniquely ambitious in proposing a mathematical formula, derived from apparently fundamental properties of conscious experience, to describe the quantity and quality of…

Neurons and Cognition · Quantitative Biology 2026-04-14 Adam B. Barrett , Borjan Milinkovic , Pedro A. M. Mediano , Fernando E. Rosas , Daniel Bor , Lionel Barnett , Anil K. Seth

The question of selecting the "best" amongst different choices is a common problem in statistics. In drug development, our motivating setting, the question becomes, for example: what is the dose that gives me a pre-specified risk of…

Statistics Theory · Mathematics 2018-03-15 Pavel Mozgunov , Thomas Jaki

Information theory is built on probability measures and by definition a probability measure has total mass 1. Probability measures are used to model uncertainty, and one may ask how important it is that the total mass is one. We claim that…

Information Theory · Computer Science 2022-02-08 Peter Harremoës

Estimation of mutual information between (multidimensional) real-valued variables is used in analysis of complex systems, biological systems, and recently also quantum systems. This estimation is a hard problem, and universally good…

Quantitative Methods · Quantitative Biology 2019-08-14 Caroline M. Holmes , Ilya Nemenman

One of the fundamental steps toward understanding a complex system is identifying variation at the scale of the system's components that is most relevant to behavior on a macroscopic scale. Mutual information provides a natural means of…

Machine Learning · Computer Science 2024-03-20 Kieran A. Murphy , Dani S. Bassett

Model selection in clustering requires (i) to specify a suitable clustering principle and (ii) to control the model order complexity by choosing an appropriate number of clusters depending on the noise level in the data. We advocate an…

Information Theory · Computer Science 2010-06-03 Joachim M. Buhmann

The purpose of this paper is to point out a new connection between information theory and dynamical systems. In the information theory side, we consider rate distortion theory, which studies lossy data compression of stochastic processes…

Dynamical Systems · Mathematics 2017-02-21 Elon Lindenstrauss , Masaki Tsukamoto

The traditional approach to the quantitative study of segregation is to employ indices that are selected by ``desirable properties''. Here, we detail how information theory underpins entropy-based indices and demonstrate how desirable…

Physics and Society · Physics 2022-12-15 Boris Barron , Yunus A. Kinkhabwala , Chriss Hess , Matthew Hall , Itai Cohen , Tomás A. Arias

We try to establish a unified information theoretic approach to learning and to explore some of its applications. First, we define {\em predictive information} as the mutual information between the past and the future of a time series,…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Ilya Nemenman

The Integrated Information Theory (IIT) might be our current best bet at a scientific explanation of phenomenal consciousness. IIT focuses on the distinctively subjective and phenomenological aspects of conscious experience. Currently, it…

Neurons and Cognition · Quantitative Biology 2025-05-06 Azenet Lopez , Carlos Montemayor

Multivariate datasets are common in various real-world applications. Recently, copulas have received significant attention for modeling dependencies among random variables. A copula-based information measure is required to quantify the…

Methodology · Statistics 2024-08-06 Mohd. Arshad , Swaroop Georgy Zachariah , Ashok Kumar Pathak

Mutual information is a general statistical dependency measure which has found applications in representation learning, causality, domain generalization and computational biology. However, mutual information estimators are typically…

Machine Learning · Statistics 2023-10-17 Paweł Czyż , Frederic Grabowski , Julia E. Vogt , Niko Beerenwinkel , Alexander Marx

Methods for addressing missing data have become much more accessible to applied researchers. However, little guidance exists to help researchers systematically identify plausible missing data mechanisms in order to ensure that these methods…

Applications · Statistics 2020-07-29 Adam Davey , Ting Dai

For biological experiments aiming at calibrating models with unknown parameters, a good experimental design is crucial, especially for those subject to various constraints, such as financial limitations, time consumption and physical…

Applications · Statistics 2014-07-22 Xiao Lin , Gabriel Terejanu