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In many biological systems, the movement of individual agents is commonly characterized as having multiple qualitatively distinct behaviors that arise from various biophysical states. This is true for vesicles in intracellular transport,…

Subcellular Processes · Quantitative Biology 2022-07-25 Maria-Veronica Ciocanel , John Fricks , Peter R. Kramer , Scott A. McKinley

A new upscaling procedure that provides 1D representations of 2D mixing-limited reactive transport systems is developed and applied. A key complication with upscaled models in this setting is that the procedure must differentiate between…

Fluid Dynamics · Physics 2022-10-05 Ricardo H. Deucher , Louis J. Durlofsky

This paper is devoted to the justification of the macroscopic, mean-field nutrient taxis system with doubly degenerate cross-diffusion proposed by Leyva et al. (2013) to model the complex spatio-temporal dynamics exhibited by the bacterium…

Analysis of PDEs · Mathematics 2017-11-09 Ramon G. Plaza

Experiments have recently shown the feasibility of utilising bacteria as micro-scale robotic devices, with special attention paid to the development of bacteria-driven micro-swimmers taking advantage of built-in actuation and sensing…

Soft Condensed Matter · Physics 2019-02-14 Christian Esparza Lopez , Albane Thery , Eric Lauga

We propose a time discretization scheme for a class of ordinary differential equations arising in simulations of fluid/particle flows. The scheme is intended to work robustly in the lubrication regime when the distance between two particles…

Numerical Analysis · Mathematics 2010-03-25 Matthieu Hillairet , Alexei Lozinski , Marcela Szopos

We present a derivation of a recently proposed theory for the time dependence of density fluctuations in stationary states of strongly interacting, athermal, self-propelled particles. The derivation consists of two steps. First, we start…

Soft Condensed Matter · Physics 2016-01-13 Grzegorz Szamel

A physical-mathematical approach to anomalous diffusion may be based on generalized diffusion equations (containing derivatives of fractional order in space or/and time) and related random walk models. The fundamental solution (for the…

Statistical Mechanics · Physics 2007-09-25 Rudolf Gorenflo , Francesco Mainardi , Daniele Moretti , Gianni Pagnini , Paolo Paradisi

Chemotaxis of the bacterium Escherichia coli is well understood in shallow chemical gradients, but its swimming behavior remains difficult to interpret in steep gradients. By focusing on single-cell trajectories from simulations, we…

Cell Behavior · Quantitative Biology 2018-02-14 Gabriele Micali , Remy Colin , Victor Sourjik , Robert G. Endres

One of simplest examples of navigation found in nature is run-and-tumble chemotaxis. Tumbles reorient cells randomly, and cells can drift toward attractants or away from repellents by biasing the frequency of these events. The post-tumble…

Soft Condensed Matter · Physics 2017-09-14 Julius B. Kirkegaard , Raymond E. Goldstein

Bacteria such as Escherichia coli (E. coli) exhibit biased motion if kept in a spatially non-uniform chemical environment. Here, we bring out unique time-dependent characteristics of bacterial chemotaxis, in response to a diffusing spatial…

Biological Physics · Physics 2018-12-05 Sibendu Samanta , Ritwik Layek , Shantimoy Kar , Sudipta Mukhopadhyay , Suman Chakraborty

We investigate the propagating profiles of a degenerate chemotaxis model describing the bacteria chemotaxis and consumption of oxygen by aerobic bacteria, in particular, the effect of the initial attractant distribution on bacterial…

Analysis of PDEs · Mathematics 2020-05-12 Tianyuan Xu , Shanming Ji , Ming Mei , Jingxue Yin

We propose a (time) multiscale method for the coarse-grained analysis of self--propelled particle models of swarms comprising a mixture of `na\"{i}ve' and `informed' individuals, used to address questions related to collective motion and…

Populations and Evolution · Quantitative Biology 2012-02-28 Michael Raghib , Simon A. Levin , Ioannis G. Kevrekidis

Mathematical models of motility are often based on random-walk descriptions of discrete individuals that can move according to certain rules. It is usually the case that large masses concentrated in small regions of space have a great…

Physics and Society · Physics 2022-11-23 Carles Falcó

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. Previous models of run and tumble chemotaxis neglect one or more features of the…

Quantitative Methods · Quantitative Biology 2007-06-26 J. T. Locsei

A discrete chemotactic predator-prey model is proposed in which the prey secrets a diffusing chemical which is sensed by the predator and vice versa. Two dynamical states corresponding to catching and escaping are identified and it is shown…

Populations and Evolution · Quantitative Biology 2015-05-20 Ankush Sengupta , Tobias Kruppa , Hartmut Löwen

We expand on a recent study of a lattice model of interacting particles [Phys. Rev. Lett. 111, 110601 (2013)]. The adsorption isotherm and equilibrium fluctuations in particle number are discussed as a function of the interaction. Their…

Statistical Mechanics · Physics 2014-11-20 T. Becker , K. Nelissen , B. Cleuren , B. Partoens , C. Van den Broeck

The purpose of this work is to propose a nonlinear non-Markovian model of subdiffusive transport that involves chemotactic substance affecting the cells at all time, not only during the jump. This leads the random waiting time to be…

Statistical Mechanics · Physics 2016-04-12 Akram Al-Sabbagh

Various bacterial strains exhibit colonial branching patterns during growth on poor substrates. These patterns reflect bacterial cooperative self-organization and cybernetic processes of communication, regulation and control employed during…

Condensed Matter · Physics 2015-06-25 Ido Golding , Yonathan Kozlovsky , Inon Cohen , Eshel Ben-Jacob

Molecular dynamics simulations are a powerful tool to study diffusion processes in battery electrolyte and electrode materials. From a single molecular dynamics simulation many properties relevant to diffusion can be obtained, including the…

Chemical Physics · Physics 2018-07-09 Niek J. J. de Klerk , Eveline van der Maas , Marnix Wagemaker

We investigate the influence of fluid flows on the propagation of chemical fronts arising in FKPP type models. We develop an asymptotic theory for the front speed in a cellular flow in the limit of small molecular diffusivity and fast…

Fluid Dynamics · Physics 2014-07-16 Alexandra Tzella , Jacques Vanneste