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The stage of evolution is the population of reproducing individuals. The structure of the population is know to affect the dynamics and outcome of evolutionary processes, but analytical results for generic random structures have been…

Populations and Evolution · Quantitative Biology 2014-07-10 Ben Adlam , Martin A. Nowak

We consider the Moran process in a graph called the "star" and obtain the asymptotic expression for the fixation probability of a single mutant when the size of the graph is large. The expression obtained corrects the previously known…

Populations and Evolution · Quantitative Biology 2016-03-21 Fabio A. C. C. Chalub

Evolution occurs in populations of reproducing individuals. In stochastic descriptions of evolutionary dynamics, such as the Moran process, individuals are chosen randomly for birth and for death. If the same type is chosen for both steps,…

Populations and Evolution · Quantitative Biology 2026-01-13 Michal Pecho , Josef Tkadlec , Martin A. Nowak

We consider the evolution of large but finite populations on arbitrary fitness landscapes. We describe the evolutionary process by a Markov, Moran process. We show that to $\mathcal O(1/N)$, the time-averaged fitness is lower for the finite…

Populations and Evolution · Quantitative Biology 2015-06-04 Dirk M. Lorenz , Jeong-Man Park , Michael W. Deem

We consider a generalized version of the birth-death (BD) and death-birth (DB) processes introduced by Kaveh, Komarova, and Kohandel (2015), in which two constant fitnesses, one for birth and the other for death, describe the selection…

Probability · Mathematics 2025-12-08 Poly H. da Silva , Max O. Souza

Moran Birth-death process is a standard stochastic process that is used to model natural selection in spatially structured populations. A newly occurring mutation that invades a population of residents can either fixate on the whole…

Populations and Evolution · Quantitative Biology 2024-10-15 Lenka Kopfová , Josef Tkadlec

In this paper, we study the absorption and fixation times for evolutionary processes on graphs, under different updating rules. While in Moran process a single neighbour is randomly chosen to be replaced, in proliferation processes other…

Populations and Evolution · Quantitative Biology 2026-01-16 Fernando Alcalde Cuesta , Gustavo Guerberoff , Álvaro Lozano Rojo

The well-known Isothermal Theorem was introduced in a Nature Communications article in 2005 and has since contributed to the creation of the rich field of evolutionary graph theory. The theorem states under which conditions certain…

Probability · Mathematics 2024-09-12 Peter Keller , Mert Ugurlu

We study stochastic evolutionary game dynamics in a population of finite size. Individuals in the population are divided into two dynamically evolving groups. The structure of the population is formally described by a Wright-Fisher type…

Probability · Mathematics 2020-07-01 Timothy Chumley , Ozgur Aydogmus , Anastasios Matzavinos , Alexander Roitershtein

We consider the modified Moran process on graphs to study the spread of genetic and cultural mutations on structured populations. An initial mutant arises either spontaneously (aka \emph{uniform initialization}), or during reproduction (aka…

Discrete Mathematics · Computer Science 2018-05-15 Andreas Pavlogiannis , Josef Tkadlec , Krishnendu Chatterjee , Martin A. Nowak

In evolutionary dynamics, the probability that a mutation spreads through the whole population, having arisen in a single individual, is known as the fixation probability. In general, it is not possible to find the fixation probability…

Populations and Evolution · Quantitative Biology 2010-10-26 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza

This work is a systematic study of discrete Markov chains that are used to describe the evolution of a two-types population. Motivated by results valid for the well-known Moran (M) and Wright-Fisher (WF) processes, we define a general class…

Populations and Evolution · Quantitative Biology 2017-05-02 Fabio A. C. C. Chalub , Max O. Souza

Biological fitness is not an observable quantity and must be inferred from population dynamics. Bayesian inference applied to the Moran process and variants yields a robust inference method that can infer fitness in populations evolving via…

Dynamical Systems · Mathematics 2013-10-24 Marc Harper

We consider the so called Moran process with frequency dependent fitness given by a certain pay-off matrix. For finite populations, we show that the final state must be homogeneous, and show how to compute the fixation probabilities. Next,…

Analysis of PDEs · Mathematics 2007-05-23 Fabio A. C. C. Chalub , Max O. Souza

Many mathematical models of evolution assume that all individuals experience the same environment. Here, we study the Moran process in heterogeneous environments. The population is of finite size with two competing types, which are exposed…

Populations and Evolution · Quantitative Biology 2018-12-19 Kamran Kaveh , Alex McAvoy , Martin A. Nowak

The Moran process models the spread of mutations in populations on graphs. We investigate the absorption time of the process, which is the time taken for a mutation introduced at a randomly chosen vertex to either spread to the whole…

Discrete Mathematics · Computer Science 2014-09-15 Josep Diaz , Leslie Ann Goldberg , David Richerby , Maria Serna

The fixation probability of a mutant in the evolutionary dynamics of Moran process is calculated by the Monte-Carlo method on a few families of clique-based graphs. It is shown that the complete suppression of fixation can be realized with…

Populations and Evolution · Quantitative Biology 2018-01-17 Jeong-Ok Choi , Unjong Yu

Finite and infinite population models are frequently used in population dynamics. However, their interrelationship is rarely discussed. In this work, we examine the limits of large populations of the Moran process (a finite-population…

Populations and Evolution · Quantitative Biology 2025-12-10 Fabio A. C. C. Chalub , Max O. Souza

The entropy rates of the Wright-Fisher process, the Moran process, and generalizations are computed and used to compare these processes and their dependence on standard evolutionary parameters. Entropy rates are measures of the variation…

Dynamical Systems · Mathematics 2014-03-26 Marc Harper

Fixation probabilities are essential for characterizing stochastic evolutionary dynamics, but analytical results remain limited mainly to systems with two competing types. We develop a perturbative framework to compute fixation…

Populations and Evolution · Quantitative Biology 2026-04-15 Ian Braga , Lucas Wardil , Ricardo Martinez-Garcia