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Temporal evolution of a clonal bacterial population is modelled taking into account reversible mutation and selection mechanisms. For the mutation model, an efficient algorithm is proposed to verify whether experimental data can be…

Populations and Evolution · Quantitative Biology 2019-04-03 C. D. Bayliss , C. Fallaize , R. Howitt , M. V. Tretyakov

Random copying is a simple model for population dynamics in the absence of selection, and has been applied to both biological and cultural evolution. In this work, we investigate the effect that spatial structure has on the dynamics. We…

Physics and Society · Physics 2015-05-26 Richard A Blythe

This paper is concerned with the evolution of haploid organisms that reproduce asexually. In a seminal piece of work, Eigen and coauthors proposed the quasispecies model in an attempt to understand such an evolutionary process. Their work…

Populations and Evolution · Quantitative Biology 2012-03-07 Narendra M. Dixit , Piyush Srivastava , Nisheeth K. Vishnoi

An organism that is newly introduced into an existing population has a survival probability that is dependent on both the population density of its environment and the competition it experiences with the members of that population.…

Populations and Evolution · Quantitative Biology 2024-12-17 Jason M. Gray , Rowan J. Barker-Clarke , Jacob G. Scott , Michael Hinczewski

Game theoretic tools are utilized to analyze a one-locus continuous selection model of sex-specific meiotic drive by considering nonequivalence of the viabilities of reciprocal heterozygotes that might be noticed at an imprinted locus. The…

Populations and Evolution · Quantitative Biology 2015-12-07 Bijan Sarkar

The rapid development of sequencing technologies represents new opportunities for population genetics research. It is expected that genomic data will increase our ability to reconstruct the history of populations. While this increase in…

Populations and Evolution · Quantitative Biology 2014-12-04 Olivier Mazet , Willy Rodríguez , Lounès Chikhi

A key question in evolution is how likely a mutant is to take over. This depends on natural selection and on stochastic fluctuations. Population spatial structure can impact mutant fixation probabilities. We introduce a model for structured…

Populations and Evolution · Quantitative Biology 2021-11-23 Loïc Marrec , Irene Lamberti , Anne-Florence Bitbol

A hallmark of bacterial populations cultured in vitro is their homogeneity of growth, where the majority of cells display identical growth rate, cell size and content. Recent insights, however, have revealed that even cells growing in…

Quantitative Methods · Quantitative Biology 2022-06-07 Santosh Pandey , Yunsoo Park , Ankita Ankita , Gregory J. Phillips

Competition between random genetic drift and natural selection plays a central role in evolution: Whereas non-beneficial mutations often prevail in small populations by chance, mutations that sweep through large populations typically confer…

Populations and Evolution · Quantitative Biology 2009-11-13 Oskar Hallatschek , Pascal Hersen , Sharad Ramanathan , David R. Nelson

Spatial patterning can be crucially important for understanding the behavior of interacting populations. Here we investigate a simple model of parasite and host populations in which parasites are random walkers that must come into contact…

Populations and Evolution · Quantitative Biology 2015-09-07 J. J. Dong , B. Skinner , N. Breecher , B. Schmittmann , R. K. P. Zia

Genetic data are often used to infer demographic history and changes or detect genes under selection. Inferential methods are commonly based on models making various strong assumptions: demography and population structures are supposed…

Populations and Evolution · Quantitative Biology 2020-07-28 Clotilde Lepers , Sylvain Billiard , Matthieu Porte , Sylvie Méléard , Viet Chi Tran

The striking variety of macroscopic morphologies displayed by bacterial colonies depends on microscopic environmental and behavioural details in a manner that is currently not well understood. A surprising example is sibling inhibition,…

Cell Behavior · Quantitative Biology 2026-05-15 Dario Buonomo , Francesco Imperi , Fabio Bruni , Marco Polin , Barbara Capone

The expansion of a population into new habitat is a transient process that leaves its footprints in the genetic composition of the expanding population. How the structure of the environment shapes the population front and the evolutionary…

Populations and Evolution · Quantitative Biology 2018-11-26 Daniel A. Beller , Kim M. J. Alards , Francesca Tesser , Ricardo A. Mosna , Federico Toschi , Wolfram Möbius

A major aim of evolutionary biology is to explain the respective roles of adaptive versus non-adaptive changes in the evolution of complexity. While selection is certainly responsible for the spread and maintenance of complex phenotypes,…

Populations and Evolution · Quantitative Biology 2017-01-17 Thomas LaBar , Christoph Adami

Understanding the influence of an environment on the evolution of its resident population is a major challenge in evolutionary biology. Great progress has been made in homogeneous population structures while heterogeneous structures have…

Populations and Evolution · Quantitative Biology 2014-07-30 Wes Maciejewski , Gregory J. Puleo

The growth and evolution of microbial populations is often subjected to advection by fluid flows in spatially extended environments, with immediate consequences for questions of spatial population genetics in marine ecology, planktonic…

Populations and Evolution · Quantitative Biology 2022-08-26 Roberto Benzi , David R. Nelson , Suraj Shankar , Federico Toschi , Xiaojue Zhu

Unraveling bacterial strategies for spatial exploration is crucial for understanding the complexity in the organization of life. Bacterial motility determines the spatio-temporal structure of microbial communities, controls infection…

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

Spatially extended population dynamics models that incorporate intrinsic noise serve as case studies for the role of fluctuations and correlations in biological systems. Including spatial structure and stochastic noise in predator-prey…

Statistical Mechanics · Physics 2018-01-09 Ulrich Dobramysl , Mauro Mobilia , Michel Pleimling , Uwe C. Täuber