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The cambium is a meristematic tissue in plant stems. Here, cell divisions occur that are required for radial growth of plant stems. Daughters of cell divisions within the cambium differentiate into woody xylem cells towards the inside of…

Cell Behavior · Quantitative Biology 2025-02-17 K. S. Bagdassarian , J. P. Etchells , N. S. Savage

Geometrical cues are known to play a very important role in neuronal growth and the formation of neuronal networks. Here, we present a detailed analysis of axonal growth and dynamics for neuronal cells cultured on patterned…

Cell Behavior · Quantitative Biology 2019-06-14 Ilya Yurchenko , Joao Marcos Vensi Basso , Vladyslav Serhiiovych Syrotenko , Cristian Staii

Actin is a key component of the cytoskeleton, which plays central roles in cell motility, division, growth, and tensile strength. To enable this wide range of transient mechanical processes and properties, networks of actin filaments…

Plants are a paradigm for active shape control in response to stimuli. For instance, it is well-known that a tilted plant will eventually straighten vertically, demonstrating the influence of both an external stimulus, gravity, and an…

Biological Physics · Physics 2025-09-09 Hadrien Oliveri , Derek E. Moulton , Heather A. Harrington , Alain Goriely

Many models have been developed to study the role of branching actin networks in motility. One important component of those models is the distribution of filament orientations relative to the cell membrane. Two mean-field models previously…

Subcellular Processes · Quantitative Biology 2013-11-04 Daniel Smith , Jian Liu

Irreversibility is a critical property of non-equilibrium transport processes. An opinion has long been insisted that the entropy production rate is a Lyapunov function for all kinds of processes, that is, the principle of minimum entropy…

Statistical Mechanics · Physics 2022-02-17 Chuan-Jin Su , Yu-Chao Hua , Zeng-Yuan Guo

A central question in developmental biology is how size and position are determined. The genetic code carries instructions on how to control these properties in order to regulate the pattern and morphology of structures in the developing…

Cell Behavior · Quantitative Biology 2016-12-05 Krishna Garikipati

We propose a stochastic model for intracellular transport processes associated with the activity of molecular motors. This out-of-equilibrium model, based on a generalized Langevin equation, considers a particle immersed in a viscoelastic…

Biological Physics · Physics 2009-04-15 L. Bruno , M. A. Despósito

A model for the dynamics of actin filament ends along the leading edge of the lamellipodium is analyzed. It contains accounts of nucleation by branching, of deactivation by capping, and of lateral flow along the leading edge by…

Analysis of PDEs · Mathematics 2015-09-28 Angelika Manhart , Christian Schmeiser

Modeling the spontaneous evolution of morphology in natural systems and its preservation by proportionate growth remains a major scientific challenge. Yet, it is conceivable that if the basic mechanisms of growth and the coupled kinetic…

Soft Condensed Matter · Physics 2020-12-30 Virginia von Streng , Rami Abi-Akl , Bianca Giovanardi , Tal Cohen

Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along…

Biological Physics · Physics 2016-11-24 Anne E. Hafner , Heiko Rieger

The approach of nonequilibrium evolution thermodynamics earlier offered is developed. It helps to describe the processes of defect formation within the adiabatic approximation. The basic equations system depends on the initial defects…

Materials Science · Physics 2015-10-23 A. V. Khomenko , D. S. Troshchenko , L. S. Metlov

Lumen formation plays an essential role in the morphogenesis of tissues during development. Here we review the physical principles that play a role in the growth and coarsening of lumens. Solute pumping by the cell, hydraulic flows driven…

Soft Condensed Matter · Physics 2021-07-14 Alejandro Torres-Sánchez , Max Kerr Winter , Guillaume Salbreux

Mammalian cell polarization and motility are important processes involved in many physiological and pathological phenomena, such as embryonic development, wound healing, and cancer metastasis. The traditional view of mammalian cell motility…

Soft Condensed Matter · Physics 2025-03-11 Winfried Schmidt , Walter Zimmermann , Chaouqi Misbah , Alexander Farutin

In this paper, we develop and analyze a minimal model for a 2D network of cross-linked actin filaments and myosin motors, representing the cortical cytoskeleton of eukaryotic cells. We implement coarse-grained representations of force…

Subcellular Processes · Quantitative Biology 2016-12-23 William M. McFadden , Patrick M. McCall , Edwin M. Munro

Molecular motors are involved in key transport processes inside actin-based cellular protrusions. The motors carry cargo proteins to the protrusion tip which participate in regulating the actin polymerization, and play a key role in…

Biological Physics · Physics 2014-06-12 Itai Pinkoviezky , Nir S Gov

Elucidating transport mechanisms and predicting transport coefficients is crucial for advancing material innovation, design, and application. Yet, state-of-the-art calculations are restricted to exact simulations of small lattices with…

Chemical Physics · Physics 2024-05-16 Srijan Bhattacharyya , Thomas Sayer , Andrés Montoya-Castillo

Large and complex molecules are building blocks for life. We compute probabilities for their formation from an average non-equilibrium model. As the distance from thermodynamic equilibrium is increased in this model, so too are the chances…

Biological Physics · Physics 2019-05-08 Elan Stopnitzky , Susanne Still

We aim to identify the control principles governing the adaptable formation of non-equilibrium structures in actomyosin networks. We build a phenomenological model and predict that biasing the energy dissipated by molecular motors should…

Absorbing phase transitions (APTs) are widespread in non-equilibrium systems, spanning condensed matter, epidemics, earthquakes, ecology, and chemical reactions. APTs feature an absorbing state in which the system becomes entrapped, along…

Statistical Mechanics · Physics 2025-12-09 R. Maire , A. Plati , M. Stockinger , E. Trizac , F. Smallenburg , G. Foffi