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The convergence to equilibrium for renormalised solutions to nonlinear reaction-diffusion systems is studied. The considered reaction-diffusion systems arise from chemical reaction networks with mass action kinetics and satisfy the complex…

Analysis of PDEs · Mathematics 2018-05-09 Klemens Fellner , Bao Q. Tang

Dynamical system models of complex biochemical reaction networks are usually high-dimensional, nonlinear, and contain many unknown parameters. In some cases the reaction network structure dictates that positive equilibria must be unique for…

Dynamical Systems · Mathematics 2008-09-09 Gheorghe Craciun , J. William Helton , Ruth J. Williams

Large time dynamics of reaction-diffusion systems modeling some irreversible reaction networks are investigated. Depending on initial masses, these networks possibly possess boundary equilibria, where some of the chemical concentrations are…

Analysis of PDEs · Mathematics 2024-11-04 Thi Lien Nguyen , Bao Quoc Tang

This paper develops the concept of decomposition for chemical reaction networks, based on which a network decomposition technique is proposed to capture the stability of large-scale networks characterized by a high number of species, high…

Dynamical Systems · Mathematics 2021-02-23 Yafei Lu , Chuanhou Gao , Denis Dochain

The long time behavior of a model for a first order, weakly reversible chemical reaction network is considered, where the movement of the reacting species is described by kinetic transport. The reactions are triggered by collisions with a…

Analysis of PDEs · Mathematics 2020-02-18 Gianluca Favre , Christian Schmeiser

A crisp survey is given of chemical reaction networks from the perspective of general nonlinear network dynamics, in particular of consensus dynamics. It is shown how by starting from the complex-balanced assumption the reaction dynamics…

Dynamical Systems · Mathematics 2015-02-10 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

We describe a large class of chemical reaction networks, those endowed with a subtle structural property called concordance. We show that the class of concordant networks coincides precisely with the class of networks which, when taken with…

Molecular Networks · Quantitative Biology 2011-09-15 Guy Shinar , Martin Feinberg

In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…

Molecular Networks · Quantitative Biology 2012-04-26 Guy Shinar , Martin Feinberg

Motivated by applications to data networks where fast convergence is essential, we analyze the problem of learning in generic N-person games that admit a Nash equilibrium in pure strategies. Specifically, we consider a scenario where…

Computer Science and Game Theory · Computer Science 2016-08-01 Johanne Cohen , Amélie Héliou , Panayotis Mertikopoulos

We discuss a method of approximate model reduction for networks of biochemical reactions. This method can be applied to networks with polynomial or rational reaction rates and whose parameters are given by their orders of magnitude. In…

Molecular Networks · Quantitative Biology 2015-05-27 Ovidiu Radulescu , Sergei Vakulenko , Dima Grigoriev

For reaction networks arising in systems biology, the capacity for two or more steady states, that is, multistationarity, is an important property that underlies biochemical switches. Another property receiving much attention recently is…

Probability · Mathematics 2023-01-26 Badal Joshi , Nidhi Kaihnsa , Tung D. Nguyen , Anne Shiu

In this work, we design a type of controller that consists of adding a specific set of reactions to an existing mass-action chemical reaction network in order to control a target species. This set of reactions is effective for both…

Molecular Networks · Quantitative Biology 2020-07-27 Jinsu Kim , German Enciso

In this paper we study the rate of convergence to the complex balanced equilibrium for some chemical reaction-diffusion systems with boundary equilibria. We first analyze a three-species system with boundary equilibria in some…

Analysis of PDEs · Mathematics 2018-12-20 Gheorghe Craciun , Jiaxin Jin , Casian Pantea , Adrian Tudorascu

Which reaction networks, when taken with mass-action kinetics, have the capacity for multiple steady states? There is no complete answer to this question, but over the last 40 years various criteria have been developed that can answer this…

Dynamical Systems · Mathematics 2015-08-21 Badal Joshi , Anne Shiu

In a recent paper by Kurasov, L\"uck, Mugnolo and Wolf, a hybrid gene regulatory network was proposed to model gene expression dynamics by using a stochastic system of coupled partial differential equations. This approach approximates…

Functional Analysis · Mathematics 2024-06-28 Alexander Dobrick , Julian Hölz

In this paper, the applicability of the entropy method for the trend towards equilibrium for reaction-diffusion systems arising from first order chemical reaction networks is studied. In particular, we present a suitable entropy structure…

Analysis of PDEs · Mathematics 2016-12-19 Klemens Fellner , Wolfgang Prager , Bao Q. Tang

An algorithm is given in this paper for the computation of dynamically equivalent weakly reversible realizations with the maximal number of reactions, for chemical reaction networks (CRNs) with mass action kinetics. The original problem…

Dynamical Systems · Mathematics 2011-07-05 Gabor Szederkenyi , Katalin M. Hangos , Zsolt Tuza

Network translation has recently been used to establish steady state properties of mass action systems by corresponding the given system to a generalized one which is either dynamically or steady state equivalent. In this work we further…

Dynamical Systems · Mathematics 2018-08-14 Elisa Tonello , Matthew D. Johnston

In an equilibrium chemical reaction mixture, the number of molecules present obeys a Poisson distribution. We ask when the same is true of the steady state of a nonequilibrium reaction network and obtain an essentially complete answer. In…

Statistical Mechanics · Physics 2013-05-29 David K. Lubensky

Chemical reaction network theory is a powerful framework to describe and analyze chemical systems. While much about the concentration profile in an equilibrium state can be determined in terms of the graph structure, the overall reaction's…

Molecular Networks · Quantitative Biology 2024-02-29 Tomoharu Suda