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Exascale computers will offer transformative capabilities to combine data-driven and learning-based approaches with traditional simulation applications to accelerate scientific discovery and insight. These software combinations and…

High-throughput computational materials discovery has promised significant acceleration of the design and discovery of new materials for many years. Despite a surge in interest and activity, the constraints imposed by large-scale…

High Performance Computing (HPC) aims at providing reasonably fast computing solutions to scientific and real life problems. The advent of multicore architectures is noticeable in the HPC history, because it has brought the underlying…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-07 Claude Tadonki

The practical realization of managing and executing large scale scientific computations efficiently and reliably is quite challenging. Scientific computations often involve thousands or even millions of tasks operating on large quantities…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-08-27 Yong Zhao , Ioan Raicu , Ian Foster , Mihael Hategan , Veronika Nefedova , Mike Wilde

Cloud computing offers on-demand, scalable computing and storage, and has become an essential resource for the analyses of big biomedical data. The usual approach to cloud computing requires users to reserve and provision virtual servers.…

Quantitative Methods · Quantitative Biology 2018-08-01 Dimitar Kumanov , Ling-Hong Hung , Wes Lloyd , Ka Yee Yeung

We propose a new scalable platform for quantum computing (QC) -- an array of optically trapped symmetric-top molecules (STMs) of the alkaline earth monomethoxide (MOCH$_3$) family. Individual STMs form qubits, and the system is readily…

Atomic Physics · Physics 2019-10-01 Phelan Yu , Lawrence W. Cheuk , Ivan Kozyryev , John M. Doyle

This study concerns with the diagnosis of aerospace structure defects by applying a HPC parallel implementation of a novel learning algorithm, named U-BRAIN. The Soft Computing approach allows advanced multi-parameter data processing in…

Artificial Intelligence · Computer Science 2016-10-19 Gianni D'Angelo , Salvatore Rampone

The increasing complexity of modern computational environments often burdens researchers with infrastructure management, authentication protocols, and container deployments. We present Sci-Orchestra, a layered orchestration framework…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Harinarayan Krishnan , Shubhabrata Mukerjee , Jeffrey Donatelli , Daniela Ushizima

In a new effort to make our research transparent and reproducible by others, we developed a workflow to run and share computational studies on the public cloud Microsoft Azure. It uses Docker containers to create an image of the application…

Computational Engineering, Finance, and Science · Computer Science 2020-07-24 Olivier Mesnard , Lorena A. Barba

Many appplications in computational science are sufficiently compute-intensive that they depend on the power of parallel computing for viability. For all but the "embarrassingly parallel" problems, the performance depends upon the level of…

High Energy Physics - Lattice · Physics 2009-09-29 Z. Sroczynski , N. Eicker , Th. Lippert , B. Orth , K. Schilling

Current approaches to designing energy-efficient applications typically rely on measuring individual components using readily available local metrics, like CPU utilization. However, these metrics fall short when applied to cloud-native…

Software Engineering · Computer Science 2025-03-12 Sebastian Werner , Maria C. Borges , Karl Wolf , Stefan Tai

We describe the design and implementation of a high performance cloud that we have used to archive, analyze and mine large distributed data sets. By a cloud, we mean an infrastructure that provides resources and/or services over the…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-08-25 Robert L Grossman , Yunhong Gu

With their high parallelism and resource needs, many scientific applications benefit from cloud deployments. Today, scientific applications are executed on dedicated pools of VMs, resulting in resource fragmentation: users pay for…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-02-23 Simon Shillaker , Carlos Segarra , Eleftheria Mappoura , Mayeul Fournial , Lluis Vilanova , Peter Pietzuch

Robust execution environments are important for addressing key challenges in quantum computing, such as application development, portability, and reproducibility, and help unlock the development of modular quantum programs, driving forward…

Quantum Physics · Physics 2025-09-26 Aleksander Wennersteen , Matthieu Moreau , Aurelien Nober , Mourad Beji

An end-to-end platform for chemical science research has been developed that integrates data from computational and experimental approaches through a modern web-based interface. The platform offers a highly interactive visualization and…

Software Engineering · Computer Science 2017-07-17 Marcus D. Hanwell , Wibe A. de Jong , Christopher J. Harris

Applications like Big Data, Machine Learning, Deep Learning and even other Engineering and Scientific research requires a lot of computing power; making High-Performance Computing (HPC) an important field. But access to Supercomputers is…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-03 Hamza Ali Imran , Saad Wazir , Ahmed Jamal Ikram , Ataul Aziz Ikram , Hanif Ullah , Maryam Ehsan

With the rise of data volume and computing power, seismological research requires more advanced skills in data processing, numerical methods, and parallel computing. We present the experience of conducting training workshops over various…

Cloud computing is a particular implementation of distributed computing. It inherited many properties of distributed computing such as scalability, reliability and distribution transparency. The transparency middle layer abstracts the…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-02-11 Bola Abimbola

Modern cloud computing platforms based on virtual machine monitors carry a variety of complex business that present many network security vulnerabilities. At present, the traditional architecture employs a number of security devices at…

Cryptography and Security · Computer Science 2014-05-06 Jin He , Mianxiong Dong , Kaoru Ota , Minyu Fan , Guangwei Wang