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The following proposition is justified from several different points of view. If you use P = 0.05 to suggest that you have made a discovery, you will be wrong at least 30 percent of the time. If, as is often the case, experiments are…

Applications · Statistics 2014-11-21 David Colquhoun

Every scientific endeavour consists of (at least) two components: A hypothesis on the one hand and data on the other. There is always a more or less abstract level - some theory, a set of concepts, certain relations of ideas - and a…

Applications · Statistics 2018-01-08 Uwe Saint-Mont

The usual procedure for estimating the significance of a peak in a power spectrum is to calculate the probability of obtaining that value or a larger value by chance (known as the "p-value"), on the assumption that the time series contains…

High Energy Astrophysical Phenomena · Physics 2009-11-13 P. A. Sturrock , J. D. Scargle

The concept of the "statistical significance" of an observation, and how it is used in particle physics experiments is reviewed. More properly known as a "p-value," the statistical foundations for this concept are reviewed from a freqentist…

High Energy Physics - Experiment · Physics 2007-05-23 Pekka K. Sinervo

It is quite common in modern research, for a researcher to test many hypotheses. The statistical (frequentist) hypothesis testing framework, does not scale with the number of hypotheses in the sense that naively performing many hypothesis…

Methodology · Statistics 2013-06-26 Jonathan Rosenblatt

For Poisson distribution $Pois(n, \lambda)$ with $\lambda \gg 1$, $n \gg 1$ we propose to determine significance as $S = \frac{n_{obs}-\lambda}{\sqrt{\lambda}}$. The significance $S$ coincides up to sign with often used significance. For…

Data Analysis, Statistics and Probability · Physics 2010-12-03 N. V. Krasnikov , S. I. Bityukov

We describe a statistical hypothesis test for the presence of a signal based on the likelihood ratio statistic. We derive the test for a case of interest and also show that for that case the test works very well, even far out in the tails…

Data Analysis, Statistics and Probability · Physics 2007-08-29 Wolfgang A. Rolke , Angel M. Lopez

Importance sampling (IS) is a widely used simulation method for estimating rare event probabilities. In IS, the relative variance of an estimator is the most common measure of estimator accuracy, and the focus of existing literature is on…

Statistics Theory · Mathematics 2026-01-05 Julie Choi , Peter Glynn

Statistically sound pattern discovery harnesses the rigour of statistical hypothesis testing to overcome many of the issues that have hampered standard data mining approaches to pattern discovery. Most importantly, application of…

Methodology · Statistics 2019-01-07 Wilhelmiina Hämäläinen , Geoffrey I. Webb

Suppose you are told that taking a statin will reduce your risk of a heart attack or stroke by 3% in the next ten years, or that women have better emotional intelligence than men. You may wonder how accurate the 3% is, or how confident we…

Other Statistics · Statistics 2018-03-19 Michael Wood

The influential claim that most published results are false raised concerns about the trustworthiness and integrity of science. Since then, there have been numerous attempts to examine the rate of false-positive results that have failed to…

Applications · Statistics 2023-09-19 Ulrich Schimmack , František Bartoš

Textbooks on statistics emphasize care and precision, via concepts such as reliability and validity in measurement, random sampling and treatment assignment in data collection, and causal identification and bias in estimation. But how do…

Methodology · Statistics 2013-07-24 Andrew Gelman , Keith O'Rourke

Hypothesis testing in high dimensional data is a notoriously difficult problem without direct access to competing models' likelihood functions. This paper argues that statistical divergences can be used to quantify the difference between…

Data Analysis, Statistics and Probability · Physics 2024-08-02 Jeremy J. H. Wilkinson , Christopher G. Lester

Importance sampling is a well developed method in statistics. Given a random variable $X$, the problem of estimating its expected value $\mu$ is addressed. The standard approach is to use the sample mean as an estimator $\bar x$. In…

Applications · Statistics 2014-05-09 Georg Hofmann

Importance sampling approximates expectations with respect to a target measure by using samples from a proposal measure. The performance of the method over large classes of test functions depends heavily on the closeness between both…

Computation · Statistics 2016-09-01 Daniel Sanz-Alonso

The paper addresses general aspects of experimental data analysis, dealing with the separation of ``signal vs. background''. It consists of two parts. Part I is a tutorial on statistical event classification, Bayesian inference, and test…

Data Analysis, Statistics and Probability · Physics 2023-06-30 Rudolf Frühwirth , Winfried Mitaroff

Null hypothesis statistical significance tests (NHST) are widely used in quantitative research in the empirical sciences including scientometrics. Nevertheless, since their introduction nearly a century ago significance tests have been…

Other Statistics · Statistics 2014-02-06 Jesper W. Schneider

Null Hypothesis Significance Testing (NHST) has long been of central importance to psychology as a science, guiding theory development and underlying the application of evidence-based intervention and decision-making. Recent years, however,…

Methodology · Statistics 2020-10-20 Fintan Costello , Paul Watts

There is a third way of implementing probability models and practicing. This is to answer questions put in terms of observables. This eliminates frequentist hypothesis testing and Bayes factors and it also eliminates parameter estimation.…

Other Statistics · Statistics 2015-08-12 William M. Briggs

Nurses should rely on the best evidence, but tend to struggle with statistics, impeding research integration into clinical practice. Statistical significance, a key concept in classical statistics, and its primary metric, the p-value, are…

Methodology · Statistics 2023-11-27 Christopher Holmberg
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